Literature DB >> 2186517

Antibody: the flexible adaptor molecule.

D R Burton1.   

Abstract

Antibodies are flexible adaptor molecules linking target and potential killer i.e. antigen and effector. With the discovery of effector binding sites on antibodies we can begin to visualize at the molecular level how this adaptor role is fulfilled.

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Year:  1990        PMID： 2186517     DOI： 10.1016/0968-0004(90)90178-e

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  12 in total

1.  Antibodies have the intrinsic capacity to destroy antigens.

Authors:  A D Wentworth; L H Jones; P Wentworth; K D Janda; R A Lerner
Journal:  Proc Natl Acad Sci U S A       Date:  2000-09-26       Impact factor: 11.205

2.  Valency of antibody binding to enveloped virus particles as determined by surface plasmon resonance.

Authors:  Sam A Hardy; Nigel J Dimmock
Journal:  J Virol       Date:  2003-01       Impact factor: 5.103

3.  Freezing immunoglobulins to see them move.

Authors:  L Bongini; D Fanelli; F Piazza; P De Los Rios; S Sandin; U Skoglund
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-13       Impact factor: 11.205

4.  The structure of dual-variable-domain immunoglobulin molecules alone and bound to antigen.

Authors:  Ivan Correia; Joyce Sung; Randall Burton; Clarissa G Jakob; Bridget Carragher; Tariq Ghayur; Czeslaw Radziejewski
Journal:  MAbs       Date:  2013-04-09       Impact factor: 5.857

5.  Rhizosecretion of a monoclonal antibody protein complex from transgenic tobacco roots.

Authors:  Pascal M W Drake; Daniel M Chargelegue; Nicholas D Vine; Craig J van Dolleweerd; Patricia Obregon; Julian K C Ma
Journal:  Plant Mol Biol       Date:  2003-05       Impact factor: 4.076

6.  Complement is activated by IgG hexamers assembled at the cell surface.

Authors:  Christoph A Diebolder; Frank J Beurskens; Rob N de Jong; Roman I Koning; Kristin Strumane; Margaret A Lindorfer; Marleen Voorhorst; Deniz Ugurlar; Sara Rosati; Albert J R Heck; Jan G J van de Winkel; Ian A Wilson; Abraham J Koster; Ronald P Taylor; Erica Ollmann Saphire; Dennis R Burton; Janine Schuurman; Piet Gros; Paul W H I Parren
Journal:  Science       Date:  2014-03-14       Impact factor: 47.728

7.  Crystal structure of deglycosylated human IgG4-Fc.

Authors:  Anna M Davies; Roy Jefferis; Brian J Sutton
Journal:  Mol Immunol       Date:  2014-06-24       Impact factor: 4.407

8.  Human IgG is produced in a pro-form that requires clipping of C-terminal lysines for maximal complement activation.

Authors:  Ewald T J van den Bremer; Frank J Beurskens; Marleen Voorhorst; Patrick J Engelberts; Rob N de Jong; Burt G van der Boom; Erika M Cook; Margaret A Lindorfer; Ronald P Taylor; Patrick Hc van Berkel; Paul Whi Parren
Journal:  MAbs       Date:  2015       Impact factor: 5.857

Review 9.  IgG cooperativity - Is there allostery? Implications for antibody functions and therapeutic antibody development.

Authors:  Danlin Yang; Rachel Kroe-Barrett; Sanjaya Singh; Christopher J Roberts; Thomas M Laue
Journal:  MAbs       Date:  2017-08-16       Impact factor: 5.857

10.  IgG Conformer's Binding to Amyloidogenic Aggregates.

Authors:  Monichan Phay; Alfred T Welzel; Angela D Williams; Helen P McWilliams-Koeppen; Veronika Blinder; Tiernan T O'Malley; Alan Solomon; Dominic M Walsh; Brian O'Nuallain
Journal:  PLoS One       Date:  2015-09-14       Impact factor: 3.240
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