Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Valency of antibody binding to enveloped virus particles as determined by surface plasmon resonance.

Literature DB >> 12502884

Valency of antibody binding to enveloped virus particles as determined by surface plasmon resonance.

Abstract

A simple method is described for determining the valency of binding of immunoglobulin G to immobilized influenza A virus. Where there is a free Fab arm (monovalent binding), a second virus particle is captured. This is detected by surface plasmon resonance. The methodology should be applicable to all enveloped and nonenveloped viruses.

Entities: Gene Species

Mesh：

Substances：
Immunoglobulin G

Year: 2003 PMID： 12502884 PMCID： PMC140826 DOI： 10.1128/jvi.77.2.1649-1652.2003

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

19 in total

1. Two influenza A virus-specific Fabs neutralize by inhibiting virus attachment to target cells, while neutralization by their IgGs is complex and occurs simultaneously through fusion inhibition and attachment inhibition.

Authors: M J Edwards; N J Dimmock
Journal: Virology Date: 2000-12-20 Impact factor: 3.616

Review 2. Structural studies on antibody interacting with viruses.

Authors: E Hewat; D Blaas
Journal: Curr Top Microbiol Immunol Date: 2001 Impact factor: 4.291

3. Different virus-precipitating activities of neutralizing monoclonal antibodies that recognize distinct sites of poliovirus particles.

Authors: K Taniguchi; S Urasawa
Journal: Arch Virol Date: 1987 Impact factor: 2.574

Review 4. Antibody: the flexible adaptor molecule.

Authors: D R Burton
Journal: Trends Biochem Sci Date: 1990-02 Impact factor: 13.807

5. A monoclonal antibody that neutralizes poliovirus by cross-linking virions.

Authors: A A Thomas; P Brioen; A Boeyé
Journal: J Virol Date: 1985-04 Impact factor: 5.103

6. Relationship between poliovirus neutralization and aggregation.

Authors: A A Thomas; R Vrijsen; A Boeyé
Journal: J Virol Date: 1986-08 Impact factor: 5.103

7. The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype).

Authors: A J Caton; G G Brownlee; J W Yewdell; W Gerhard
Journal: Cell Date: 1982-12 Impact factor: 41.582

8. Flexibility of the major antigenic loop of foot-and-mouth disease virus bound to a Fab fragment of a neutralising antibody: structure and neutralisation.

Authors: N Verdaguer; G Schoehn; W F Ochoa; I Fita; S Brookes; A King; E Domingo; M G Mateu; D Stuart; E A Hewat
Journal: Virology Date: 1999-03-15 Impact factor: 3.616

9. Structure of human rhinovirus complexed with Fab fragments from a neutralizing antibody.

Authors: T J Smith; N H Olson; R H Cheng; H Liu; E S Chase; W M Lee; D M Leippe; A G Mosser; R R Rueckert; T S Baker
Journal: J Virol Date: 1993-03 Impact factor: 5.103

10. Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. I. Significant variation in repertoire expression between individual mice.

Authors: L M Staudt; W Gerhard
Journal: J Exp Med Date: 1983-02-01 Impact factor: 14.307

4 in total

1. Virus-neutralizing activity mediated by the Fab fragment of a hemagglutinin-specific antibody is sufficient for the resolution of influenza virus infection in SCID mice.

Authors: Krystyna Mozdzanowska; Jingqi Feng; Walter Gerhard
Journal: J Virol Date: 2003-08 Impact factor: 5.103