Literature DB >> 21863803

Enhanced mechanical rigidity of hydrogels formed from enantiomeric peptide assemblies.

Katelyn J Nagy1, Michael C Giano, Albert Jin, Darrin J Pochan, Joel P Schneider.   

Abstract

Chirality can be used as a design tool to control the mechanical rigidity of hydrogels formed from self-assembling peptides. Hydrogels prepared from enantiomeric mixtures of self-assembling β-hairpins show nonadditive, synergistic, enhancement in material rigidity compared to gels prepared from either pure enantiomer, with the racemic hydrogel showing the greatest effect. CD spectroscopy, TEM, and AFM indicate that this enhancement is defined by nanoscale interactions between enantiomers in the self-assembled state.

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Year:  2011        PMID: 21863803      PMCID: PMC3202337          DOI: 10.1021/ja206742m

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  24 in total

1.  A reductive trigger for peptide self-assembly and hydrogelation.

Authors:  Charles J Bowerman; Bradley L Nilsson
Journal:  J Am Chem Soc       Date:  2010-07-21       Impact factor: 15.419

Review 2.  Synthesis and primary characterization of self-assembled peptide-based hydrogels.

Authors:  Radhika P Nagarkar; Joel P Schneider
Journal:  Methods Mol Biol       Date:  2008

3.  Enzyme-instructed molecular self-assembly confers nanofibers and a supramolecular hydrogel of taxol derivative.

Authors:  Yuan Gao; Yi Kuang; Zu-Feng Guo; Zhihong Guo; Isaac J Krauss; Bing Xu
Journal:  J Am Chem Soc       Date:  2009-09-30       Impact factor: 15.419

4.  A metal-collagen peptide framework for three-dimensional cell culture.

Authors:  Marcos M Pires; David E Przybyla; Jean Chmielewski
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

5.  Dependence of Self-Assembled Peptide Hydrogel Network Structure on Local Fibril Nanostructure.

Authors:  Rohan A Hule; Radhika P Nagarkar; Boualem Hammouda; Joel P Schneider; Darrin J Pochan
Journal:  Macromolecules       Date:  2009       Impact factor: 5.985

6.  In-situ formation of biodegradable hydrogels by stereocomplexation of PEG-(PLLA)8 and PEG-(PDLA)8 star block copolymers.

Authors:  Christine Hiemstra; Zhiyuan Zhong; Liangbin Li; Pieter J Dijkstra; Jan Feijen
Journal:  Biomacromolecules       Date:  2006-10       Impact factor: 6.988

Review 7.  Peptide-directed self-assembly of hydrogels.

Authors:  Jindrich Kopecek; Jiyuan Yang
Journal:  Acta Biomater       Date:  2008-10-14       Impact factor: 8.947

8.  Fast dynamics of semiflexible chain networks of self-assembled peptides.

Authors:  Monica C Branco; Florian Nettesheim; Darrin J Pochan; Joel P Schneider; Norman J Wagner
Journal:  Biomacromolecules       Date:  2009-06-08       Impact factor: 6.988

9.  Direct Observation of Early-Time Hydrogelation in beta-Hairpin Peptide Self-Assembly.

Authors:  Tuna Yucel; Chris M Micklitsch; Joel P Schneider; Darrin J Pochan
Journal:  Macromolecules       Date:  2008-07-01       Impact factor: 5.985

Review 10.  Interpenetrating polymer networks as a route to tunable multi-responsive biomaterials: development of novel concepts.

Authors:  L Kris Kostanski; Ruixiang Huang; Carlos D M Filipe; Raja Ghosh
Journal:  J Biomater Sci Polym Ed       Date:  2009       Impact factor: 3.517

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  49 in total

1.  Molecular structure of monomorphic peptide fibrils within a kinetically trapped hydrogel network.

Authors:  Katelyn Nagy-Smith; Eric Moore; Joel Schneider; Robert Tycko
Journal:  Proc Natl Acad Sci U S A       Date:  2015-07-27       Impact factor: 11.205

Review 2.  Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials.

Authors:  Xuewen Du; Jie Zhou; Junfeng Shi; Bing Xu
Journal:  Chem Rev       Date:  2015-12-08       Impact factor: 60.622

3.  Synergistic Interactions Are Prevalent in Catalytic Amyloids.

Authors:  Liam R Marshall; Megha Jayachandran; Zsofia Lengyel-Zhand; Caroline M Rufo; Austin Kriews; Min-Chul Kim; Ivan V Korendovych
Journal:  Chembiochem       Date:  2020-06-09       Impact factor: 3.164

4.  Coassembly of enantiomeric amphipathic peptides into amyloid-inspired rippled β-sheet fibrils.

Authors:  Ria J Swanekamp; John T M DiMaio; Charles J Bowerman; Bradley L Nilsson
Journal:  J Am Chem Soc       Date:  2012-03-16       Impact factor: 15.419

5.  Self-assembly of nucleopeptides to interact with DNAs.

Authors:  Xuewen Du; Jie Zhou; Xinming Li; Bing Xu
Journal:  Interface Focus       Date:  2017-10-20       Impact factor: 3.906

6.  Design of a Peptide-Based Electronegative Hydrogel for the Direct Encapsulation, 3D Culturing, in Vivo Syringe-Based Delivery, and Long-Term Tissue Engraftment of Cells.

Authors:  Y Yamada; N L Patel; J D Kalen; J P Schneider
Journal:  ACS Appl Mater Interfaces       Date:  2019-09-13       Impact factor: 9.229

7.  Mixing biomimetic heterodimers of nucleopeptides to generate biocompatible and biostable supramolecular hydrogels.

Authors:  Dan Yuan; Xuewen Du; Junfeng Shi; Ning Zhou; Jie Zhou; Bing Xu
Journal:  Angew Chem Int Ed Engl       Date:  2015-03-17       Impact factor: 15.336

8.  Instant Hydrogelation Inspired by Inflammasomes.

Authors:  Huaimin Wang; Zhaoqianqi Feng; Alvin Lu; Yujie Jiang; Hao Wu; Bing Xu
Journal:  Angew Chem Int Ed Engl       Date:  2017-05-24       Impact factor: 15.336

9.  Self-Assembly for the Synthesis of Functional Biomaterials.

Authors:  Nicholas Stephanopoulos; Julia H Ortony; Samuel I Stupp
Journal:  Acta Mater       Date:  2013-02-01       Impact factor: 8.203

10.  Protein release from highly charged peptide hydrogel networks.

Authors:  Katelyn Nagy-Smith; Yuji Yamada; Joel P Schneider
Journal:  J Mater Chem B       Date:  2016-02-26       Impact factor: 6.331

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