| Literature DB >> 21863803 |
Katelyn J Nagy1, Michael C Giano, Albert Jin, Darrin J Pochan, Joel P Schneider.
Abstract
Chirality can be used as a design tool to control the mechanical rigidity of hydrogels formed from self-assembling peptides. Hydrogels prepared from enantiomeric mixtures of self-assembling β-hairpins show nonadditive, synergistic, enhancement in material rigidity compared to gels prepared from either pure enantiomer, with the racemic hydrogel showing the greatest effect. CD spectroscopy, TEM, and AFM indicate that this enhancement is defined by nanoscale interactions between enantiomers in the self-assembled state.Entities:
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Year: 2011 PMID: 21863803 PMCID: PMC3202337 DOI: 10.1021/ja206742m
Source DB: PubMed Journal: J Am Chem Soc ISSN: 0002-7863 Impact factor: 15.419