Literature DB >> 2185905

Chirality. Clinical pharmacokinetic and pharmacodynamic considerations.

E J Lee1, K M Williams.   

Abstract

Mesh：

Year:  1990        PMID： 2185905     DOI： 10.2165/00003088-199018050-00001

Source DB:  PubMed          Journal:  Clin Pharmacokinet        ISSN： 0312-5963            Impact factor:   6.447


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  37 in total

1.  Stereoselective disposition of ibuprofen enantiomers in synovial fluid.

Authors:  R O Day; K M Williams; G G Graham; E J Lee; R D Knihinicki; G D Champion
Journal:  Clin Pharmacol Ther       Date:  1988-05       Impact factor: 6.875

2.  Clinical pharmacology of the stereoisomers of leucovorin during repeated oral dosing.

Authors:  R L Schilsky; K E Choi; E E Vokes; A Guaspari; C Guarnieri; S Whaling; M A Liebner
Journal:  Cancer       Date:  1989-03-15       Impact factor: 6.860

3.  Bias in pharmacokinetics and clinical pharmacology.

Authors:  E J Ariëns; E W Wuis
Journal:  Clin Pharmacol Ther       Date:  1987-10       Impact factor: 6.875

4.  Toxicological and local anaesthetic effects of optically active isomers of two local anaesthetic compounds.

Authors:  G Aberg
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1972

Review 5.  Importance of drug enantiomers in clinical pharmacology.

Authors:  K Williams; E Lee
Journal:  Drugs       Date:  1985-10       Impact factor: 9.546

6.  Antagonism of slow reacting substance in anaphylaxis (SRS-A) and other spasmogens on the guinea pig tracheal chain by hydratropic acids and their effects on anaphylaxis.

Authors:  M E Greig; R L Griffin
Journal:  J Med Chem       Date:  1975-01       Impact factor: 7.446

7.  Pharmacology of ketamine isomers in surgical patients.

Authors:  P F White; J Ham; W L Way; A J Trevor
Journal:  Anesthesiology       Date:  1980-03       Impact factor: 7.892

8.  Stereoselective disposition of ibuprofen enantiomers in man.

Authors:  E J Lee; K Williams; R Day; G Graham; D Champion
Journal:  Br J Clin Pharmacol       Date:  1985-05       Impact factor: 4.335

9.  Stereoselective secretion of atenolol from PC12 cells.

Authors:  J G Webb; J A Street; E E Bagwell; T Walle; T E Gaffney
Journal:  J Pharmacol Exp Ther       Date:  1988-12       Impact factor: 4.030

10.  Classification of opioids on the basis of change in seizure threshold in rats.

Authors:  A Cowan; E B Geller; M W Adler
Journal:  Science       Date:  1979-10-26       Impact factor: 47.728
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  13 in total

1.  Chirality and drugs used to treat psychiatric disorders.

Authors:  Glen B Baker; Trevor I Prior; Ronald T Coutts
Journal:  J Psychiatry Neurosci       Date:  2002-11       Impact factor: 6.186

2.  On the development of alternative antiepileptic drugs. Lack of enantioselectivity of the anticonvulsant activity, in contrast to teratogenicity, of 2-n-propyl-4-pentenoic acid and 2-n-propyl-4-pentynoic acid, analogues of the anticonvulsant drug valproic acid.

Authors:  R S Hauck; H Nau; M M Elmazar
Journal:  Naturwissenschaften       Date:  1991-06

3.  Need for precise chiral nomenclature.

Authors:  E Lee; K Williams
Journal:  Clin Pharmacokinet       Date:  1990-12       Impact factor: 6.447

Review 4.  Chirality and nonsteroidal anti-inflammatory drugs.

Authors:  P J Hayball
Journal:  Drugs       Date:  1996       Impact factor: 9.546

Review 5.  Bioequivalence of chiral drugs. Stereospecific versus non-stereospecific methods.

Authors:  R Mehvar; F Jamali
Journal:  Clin Pharmacokinet       Date:  1997-08       Impact factor: 6.447

6.  Stereoselective pharmacokinetics of ifosfamide in male and female rats.

Authors:  J J Wang; H Lu; K K Chan
Journal:  AAPS PharmSci       Date:  2000

Review 7.  Chirality in new drug development. Clinical pharmacokinetic considerations.

Authors:  R L Nation
Journal:  Clin Pharmacokinet       Date:  1994-10       Impact factor: 6.447

8.  Disposition of ibuprofen in patients with liver cirrhosis. Stereochemical considerations.

Authors:  G Li; G Treiber; K Maier; S Walker; U Klotz
Journal:  Clin Pharmacokinet       Date:  1993-08       Impact factor: 6.447

9.  Levobupivacaine for epidural anaesthesia and postoperative analgesia in hip surgery: a multi-center efficacy and safety equivalence study with bupivacaine and ropivacaine.

Authors:  T Koch; A Fichtner; U Schwemmer; T Standl; T Volk; K Engelhard; M F Stevens; C Putzke; J Scholz; M Zenz; J Motsch; V Hempel; A Heinrichs; B Zwissler
Journal:  Anaesthesist       Date:  2008-05       Impact factor: 1.041

Review 10.  Chirality and drugs used in psychiatry: nice to know or need to know?

Authors:  R M Lane; G B Baker
Journal:  Cell Mol Neurobiol       Date:  1999-06       Impact factor: 5.046
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