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Literature DB >> 21858356

Dendron-mediated self-assembly of highly PEGylated block copolymers: a modular nanocarrier platform.

Jin Woo Bae¹, Ryan M Pearson, Niladri Patra, Suhair Sunoqrot, Lela Vuković, Petr Král, Seungpyo Hong.

Abstract

PEGylated dendron coils (PDCs) were investigated as a novel potential nanocarrier platform. PDCs self-assembled into micelles at lower CMCs than linear copolymer counterparts by 1-2 orders of magnitude, due to the unique architecture of dendrons. MD simulations also supported thermodynamically favourable self-assembly mediated by dendrons. This journal is © The Royal Society of Chemistry 2011

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Year: 2011 PMID： 21858356 PMCID： PMC3190671 DOI： 10.1039/c1cc14331j

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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2. Inhibition of influenza virus infection by multivalent sialic-acid-functionalized gold nanoparticles.

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3. Advanced drug delivery systems that target the vascular endothelium.

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4. A precise packing sequence for self-assembled convex structures.

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5. The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform.

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6. In vivo fate of unimers and micelles of a poly(ethylene glycol)-block-poly(caprolactone) copolymer in mice following intravenous administration.

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7. RGD dendron bodies; synthetic avidity agents with defined and potentially interchangeable effector sites that can substitute for antibodies.

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8. Computer simulation of architectural and molecular weight effects on the assembly of amphiphilic linear-dendritic block copolymers in solution.

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9. Ligand-clustered "patchy" nanoparticles for modulated cellular uptake and in vivo tumor targeting.

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10. Precisely defined protein-polymer conjugates: construction of synthetic DNA binding domains on proteins by using multivalent dendrons.

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21 in total

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2. Effect of size, surface charge, and hydrophobicity of poly(amidoamine) dendrimers on their skin penetration.

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Dendron-mediated self-assembly of highly PEGylated block copolymers: a modular nanocarrier platform.

1. The first account of a structurally persistent micelle.

2. Inhibition of influenza virus infection by multivalent sialic-acid-functionalized gold nanoparticles.

3. Advanced drug delivery systems that target the vascular endothelium.

4. A precise packing sequence for self-assembled convex structures.

5. The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform.

6. In vivo fate of unimers and micelles of a poly(ethylene glycol)-block-poly(caprolactone) copolymer in mice following intravenous administration.

7. RGD dendron bodies; synthetic avidity agents with defined and potentially interchangeable effector sites that can substitute for antibodies.

8. Computer simulation of architectural and molecular weight effects on the assembly of amphiphilic linear-dendritic block copolymers in solution.

9. Ligand-clustered "patchy" nanoparticles for modulated cellular uptake and in vivo tumor targeting.

10. Precisely defined protein-polymer conjugates: construction of synthetic DNA binding domains on proteins by using multivalent dendrons.

1. Dendrimer-mediated multivalent binding for the enhanced capture of tumor cells.

2. Effect of size, surface charge, and hydrophobicity of poly(amidoamine) dendrimers on their skin penetration.

3. Temporal control over cellular targeting through hybridization of folate-targeted dendrimers and PEG-PLA nanoparticles.

4. In vitro evaluation of dendrimer-polymer hybrid nanoparticles on their controlled cellular targeting kinetics.

5. Dendritic PEG outer shells enhance serum stability of polymeric micelles.

6. Redox-Responsive, Core Cross-Linked Polyester Micelles.

7. Supramolecular nanostructures formed by anticancer drug assembly.

8. Positively Charged Dendron Micelles Display Negligible Cellular Interactions.

9. Recent advances in targeted drug delivery approaches using dendritic polymers.

10. Tuning the Selectivity of Dendron Micelles Through Variations of the Poly(ethylene glycol) Corona.