BACKGROUND: In the treatment of superficial partial-thickness burns, various skin substitutes and temporary dressings offer potential advantages over traditional treatments. Nonetheless, the search for an ideal temporary skin substitute or biosynthetic wound dressing is still a continuous quest. This research aimed to provide objective data on the long-term outcome of Biobrane(®) and Suprathel(®). METHODS: Eight months after the initial burn treatment of Biobrane(®) and Suprathel(®), skin elasticity was measured objectively using a Cutometer(®) and the scarring process was quantified using the Vancouver Scar Scale (VSS). RESULTS: The median healing time for patients treated with Biobrane(®) was up to 1.8 days shorter then the Suprathel(®) group. Regarding the Vancouver Scar Scale (VSS), neither the single parameter, nor the total score were significantly different in both groups. In comparison, the Biobrane(®) group demonstrated superior Cutometer(®) parameters in regards to maximal extension, elasticity, retraction and pliability. Despite higher levels of Biobrane(®) group, the differences in the viscoelastic analysis of both substitutes did not vary significantly. CONCLUSION: Using both substitutes, we observed satisfying results in superficial partial-thickness burn treatment, without any significant differences. Since the treatment of burned patients is associated with high socioeconomic load, the cost factor should be one of the most important criteria in dermal substitute selection.
BACKGROUND: In the treatment of superficial partial-thickness burns, various skin substitutes and temporary dressings offer potential advantages over traditional treatments. Nonetheless, the search for an ideal temporary skin substitute or biosynthetic wound dressing is still a continuous quest. This research aimed to provide objective data on the long-term outcome of Biobrane(®) and Suprathel(®). METHODS: Eight months after the initial burn treatment of Biobrane(®) and Suprathel(®), skin elasticity was measured objectively using a Cutometer(®) and the scarring process was quantified using the Vancouver Scar Scale (VSS). RESULTS: The median healing time for patients treated with Biobrane(®) was up to 1.8 days shorter then the Suprathel(®) group. Regarding the Vancouver Scar Scale (VSS), neither the single parameter, nor the total score were significantly different in both groups. In comparison, the Biobrane(®) group demonstrated superior Cutometer(®) parameters in regards to maximal extension, elasticity, retraction and pliability. Despite higher levels of Biobrane(®) group, the differences in the viscoelastic analysis of both substitutes did not vary significantly. CONCLUSION: Using both substitutes, we observed satisfying results in superficial partial-thickness burn treatment, without any significant differences. Since the treatment of burned patients is associated with high socioeconomic load, the cost factor should be one of the most important criteria in dermal substitute selection.
Authors: Gabriel Hundeshagen; Vanessa N Collins; Paul Wurzer; William Sherman; Charles D Voigt; Janos Cambiaso-Daniel; Omar Nunez Lopez; Jason Sheaffer; David N Herndon; Celeste C Finnerty; Ludwik K Branski Journal: J Burn Care Res Date: 2018-02-20 Impact factor: 1.845
Authors: Ela J Hyland; Rachel D'Cruz; Seema Menon; John G Harvey; Erik La Hei; Torey Lawrence; Kelly Waddell; Mitchell Nash; Andrew Ja Holland Journal: Int J Burns Trauma Date: 2018-06-20
Authors: Adam M Jorgensen; Mathew Varkey; Anastasiya Gorkun; Cara Clouse; Lei Xu; Zishuai Chou; Sean V Murphy; Joseph Molnar; Sang Jin Lee; James J Yoo; Shay Soker; Anthony Atala Journal: Tissue Eng Part A Date: 2020-01-28 Impact factor: 3.845
Authors: Aleksander Skardal; David Mack; Edi Kapetanovic; Anthony Atala; John D Jackson; James Yoo; Shay Soker Journal: Stem Cells Transl Med Date: 2012-10-29 Impact factor: 6.940
Authors: Jean-Paul Pirnay; Alain Vanderkelen; Nadine Ectors; Christian Delloye; Denis Dufrane; Etienne Baudoux; Michel Van Brussel; Michael P Casaer; Daniel De Vos; Jean-Pierre Draye; Thomas Rose; Serge Jennes; Pierre Neirinckx; Geert Laire; Martin Zizi; Gilbert Verbeken Journal: Cell Tissue Bank Date: 2012-06-21 Impact factor: 1.522