Literature DB >> 34054388

Our Initial Experience In The Customized Treatment Of Donor Site And Burn Wounds With A New Nanofibrous Temporary Epidermal Layer.

A Schulz1, P C Fuchs1, W Heitzmann1, C H Kanho1, J L Schiefer1.   

Abstract

Recently, electrospinning technology has gained increasing attention for wound care. SpinCare™ electrospun polymer nanofibrous temporary epidermal layer is one of the latest developments in the market. Our objective was to explore the potential use of the new SpinCare™ system for treating burns and wounds. We conducted a single-center prospective observational trial, treating 10 patients with superficial to partial thickness wounds including burn wounds with a nanofibrous dressing. Treatment was evaluated, including procedures, place of injury, treatment times, ease of use etc. Ten superficial to deep dermal wounds were treated successfully. Inexperienced users learned the handling of the device quickly. Covering difficult-to-access wound surfaces was challenging. One leading problem is that the product is nearly opaque once applied on the moist wound. We introduced a standardized 3-day treatment protocol. After application, wounds were covered with a silicon layer for 2 days. The nanofibrous dressing appeared to be suitable following enzymatic debridement in burn wounds. Because there is a risk of wounds drying out under the dressing, the application should probably be limited to superficial and partial thickness wounds if not combined with other treatment options. The electrospun polymer nanofibrous temporary epidermal layer shows promising results in the treatment of superficial to partial thickness wounds including burns. However, minor improvements might help to optimize its usage and thus take full advantage of all existing treatment options.
Copyright © 2021 Euro-Mediterranean Council for Burns and Fire Disasters.

Entities:  

Keywords:  aesthetic and functional outcome; antimicrobial; burn wounds; customized; electrospun polymer; nanofibrous dressing; superficial wounds

Year:  2021        PMID: 34054388      PMCID: PMC8126369     

Source DB:  PubMed          Journal:  Ann Burns Fire Disasters        ISSN: 1592-9558


  27 in total

Review 1.  Electrospinning strategies of drug-incorporated nanofibrous mats for wound recovery.

Authors:  Ji Suk Choi; Hye Sung Kim; Hyuk Sang Yoo
Journal:  Drug Deliv Transl Res       Date:  2015-04       Impact factor: 4.617

2.  Enzymatic debridement of deeply burned faces: Healing and early scarring based on tissue preservation compared to traditional surgical debridement.

Authors:  Alexandra Schulz; Paul Christian Fuchs; Irene Rothermundt; Alexandra Hoffmann; Lior Rosenberg; Yaron Shoham; Henrik Oberländer; Jennifer Schiefer
Journal:  Burns       Date:  2017-03-28       Impact factor: 2.744

3.  In vitro culture of human dermal fibroblasts on electrospun polycaprolactone collagen nanofibrous membrane.

Authors:  Jayarama Reddy Venugopal; Yanzhong Zhang; Seeram Ramakrishna
Journal:  Artif Organs       Date:  2006-06       Impact factor: 3.094

Review 4.  Dressings for superficial and partial thickness burns.

Authors:  Jason Wasiak; Heather Cleland; Fiona Campbell; Anneliese Spinks
Journal:  Cochrane Database Syst Rev       Date:  2013-03-28

Review 5.  Electrospun nanofibers as dressings for chronic wound care: advances, challenges, and future prospects.

Authors:  Martina Abrigo; Sally L McArthur; Peter Kingshott
Journal:  Macromol Biosci       Date:  2014-03-28       Impact factor: 4.979

6.  Effectiveness of Biobrane for treatment of partial-thickness burns in children.

Authors:  Aaron P Lesher; Ryan H Curry; Jill Evans; Valerie A Smith; Michael T Fitzgerald; Robert A Cina; Christian J Streck; Andre V Hebra
Journal:  J Pediatr Surg       Date:  2011-09       Impact factor: 2.545

7.  A novel rapid and selective enzymatic debridement agent for burn wound management: a multi-center RCT.

Authors:  Lior Rosenberg; Yuval Krieger; Alex Bogdanov-Berezovski; Eldad Silberstein; Yaron Shoham; Adam J Singer
Journal:  Burns       Date:  2013-09-26       Impact factor: 2.744

8.  Nanofibers prepared by needleless electrospinning technology as scaffolds for wound healing.

Authors:  Michal Dubský; Sárka Kubinová; Jakub Sirc; Luděk Voska; Robert Zajíček; Alena Zajícová; Petr Lesný; Alexandra Jirkovská; Jiří Michálek; Marcela Munzarová; Vladimír Holáň; Eva Syková
Journal:  J Mater Sci Mater Med       Date:  2012-02-14       Impact factor: 3.896

9.  Evaluation of scar quality after treatment of superficial burns of the hands and face with Dressilk or Biobrane-An intra-individual comparison.

Authors:  Jennifer Lynn Schiefer; Rebekka Rath; Elena Ahrens; Daniel Grigutsch; Ingo Gräff; Jan-Philipp Stromps; Paul Christian Fuchs; Alexandra Schulz
Journal:  Burns       Date:  2017-08-31       Impact factor: 2.744

10.  Curcumin-loaded poly(epsilon-caprolactone) nanofibres: diabetic wound dressing with anti-oxidant and anti-inflammatory properties.

Authors:  Jonathan G Merrell; Shaun W McLaughlin; Lu Tie; Cato T Laurencin; Alex F Chen; Lakshmi S Nair
Journal:  Clin Exp Pharmacol Physiol       Date:  2009-05-19       Impact factor: 2.557

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  1 in total

Review 1.  Evaluating polymeric biomaterials to improve next generation wound dressing design.

Authors:  Jacob G Hodge; David S Zamierowski; Jennifer L Robinson; Adam J Mellott
Journal:  Biomater Res       Date:  2022-10-01
  1 in total

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