Literature DB >> 21818494

High-throughput age synchronisation of Caenorhabditis elegans.

Xavier Casadevall i Solvas1, Florian M Geier, Armand M Leroi, Jake G Bundy, Joshua B Edel, Andrew J DeMello.   

Abstract

We present a passive microfluidic strategy for sorting adult C. elegans nematodes on the basis of age and size. The separation mechanism takes advantage of phenotypic differences between 'adult' and 'juvenile' organisms and their behaviour in microfluidic architectures. In brief, the microfluidic device allows worms to sort themselves in a passive manner.

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Year:  2011        PMID: 21818494     DOI: 10.1039/c1cc14076k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  10 in total

1.  A hydrodynamic mechanism for attraction of undulatory microswimmers to surfaces (bordertaxis).

Authors:  Jinzhou Yuan; David M Raizen; Haim H Bau
Journal:  J R Soc Interface       Date:  2015-08-06       Impact factor: 4.118

2.  Chip in a lab: Microfluidics for next generation life science research.

Authors:  Aaron M Streets; Yanyi Huang
Journal:  Biomicrofluidics       Date:  2013-01-31       Impact factor: 2.800

3.  Why do worms go against the flow? C. elegans behaviors explained by simple physics.

Authors:  Haim H Bau; David Raizen; Jinzhou Yuan
Journal:  Worm       Date:  2015-12-02

4.  A high-throughput device for size based separation of C. elegans developmental stages.

Authors:  Xiaoni Ai; Weipeng Zhuo; Qionglin Liang; Patrick T McGrath; Hang Lu
Journal:  Lab Chip       Date:  2014-03-27       Impact factor: 6.799

5.  Propensity of undulatory swimmers, such as worms, to go against the flow.

Authors:  Jinzhou Yuan; David M Raizen; Haim H Bau
Journal:  Proc Natl Acad Sci U S A       Date:  2015-03-09       Impact factor: 11.205

Review 6.  Geroscience approaches to increase healthspan and slow aging.

Authors:  Simon Melov
Journal:  F1000Res       Date:  2016-04-29

Review 7.  Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans.

Authors:  Bhagwati P Gupta; Pouya Rezai
Journal:  Micromachines (Basel)       Date:  2016-07-19       Impact factor: 2.891

Review 8.  Microfluidic Devices in Advanced Caenorhabditis elegans Research.

Authors:  Muniesh Muthaiyan Shanmugam; Tuhin Subhra Santra
Journal:  Molecules       Date:  2016-08-02       Impact factor: 4.411

Review 9.  Microfluidic Technologies for High Throughput Screening Through Sorting and On-Chip Culture of C. elegans.

Authors:  Daniel Midkiff; Adriana San-Miguel
Journal:  Molecules       Date:  2019-11-25       Impact factor: 4.411

10.  NeuroChip: a microfluidic electrophysiological device for genetic and chemical biology screening of Caenorhabditis elegans adult and larvae.

Authors:  Chunxiao Hu; James Dillon; James Kearn; Caitriona Murray; Vincent O'Connor; Lindy Holden-Dye; Hywel Morgan
Journal:  PLoS One       Date:  2013-05-22       Impact factor: 3.240

  10 in total

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