Literature DB >> 23460772

Chip in a lab: Microfluidics for next generation life science research.

Aaron M Streets1, Yanyi Huang.   

Abstract

Microfluidic circuits are characterized by fluidic channels and chambers with a linear dimension on the order of tens to hundreds of micrometers. Components of this size enable lab-on-a-chip technology that has much promise, for example, in the development of point-of-care diagnostics. Micro-scale fluidic circuits also yield practical, physical, and technological advantages for studying biological systems, enhancing the ability of researchers to make more precise quantitative measurements. Microfluidic technology has thus become a powerful tool in the life science research laboratory over the past decade. Here we focus on chip-in-a-lab applications of microfluidics and survey some examples of how small fluidic components have provided researchers with new tools for life science research.

Year:  2013        PMID: 23460772      PMCID: PMC3574129          DOI: 10.1063/1.4789751

Source DB:  PubMed          Journal:  Biomicrofluidics        ISSN: 1932-1058            Impact factor:   2.800


  90 in total

1.  A programmable droplet-based microfluidic device applied to multiparameter analysis of single microbes and microbial communities.

Authors:  Kaston Leung; Hans Zahn; Timothy Leaver; Kishori M Konwar; Niels W Hanson; Antoine P Pagé; Chien-Chi Lo; Patrick S Chain; Steven J Hallam; Carl L Hansen
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-30       Impact factor: 11.205

2.  Density-dependent separation of encapsulated cells in a microfluidic channel by using a standing surface acoustic wave.

Authors:  Jeonghun Nam; Hyunjung Lim; Choong Kim; Ji Yoon Kang; Sehyun Shin
Journal:  Biomicrofluidics       Date:  2012-05-16       Impact factor: 2.800

3.  A perspective on paper-based microfluidics: Current status and future trends.

Authors:  Xu Li; David R Ballerini; Wei Shen
Journal:  Biomicrofluidics       Date:  2012-03-02       Impact factor: 2.800

4.  Microfluidic very large scale integration (mVLSI) with integrated micromechanical valves.

Authors:  Ismail Emre Araci; Stephen R Quake
Journal:  Lab Chip       Date:  2012-06-19       Impact factor: 6.799

Review 5.  Genomic sequencing of uncultured microorganisms from single cells.

Authors:  Roger S Lasken
Journal:  Nat Rev Microbiol       Date:  2012-09       Impact factor: 60.633

6.  Genome-wide single-cell analysis of recombination activity and de novo mutation rates in human sperm.

Authors:  Jianbin Wang; H Christina Fan; Barry Behr; Stephen R Quake
Journal:  Cell       Date:  2012-07-20       Impact factor: 41.582

7.  Digital polymerase chain reaction in an array of femtoliter polydimethylsiloxane microreactors.

Authors:  Yongfan Men; Yusi Fu; Zitian Chen; Peter A Sims; William J Greenleaf; Yanyi Huang
Journal:  Anal Chem       Date:  2012-04-12       Impact factor: 6.986

8.  Structural haplotypes and recent evolution of the human 17q21.31 region.

Authors:  Linda M Boettger; Robert E Handsaker; Michael C Zody; Steven A McCarroll
Journal:  Nat Genet       Date:  2012-07-01       Impact factor: 38.330

9.  High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation.

Authors:  Angela R Wu; Tiara L A Kawahara; Nicole A Rapicavoli; Jan van Riggelen; Emelyn H Shroff; Liwen Xu; Dean W Felsher; Howard Y Chang; Stephen R Quake
Journal:  Lab Chip       Date:  2012-05-08       Impact factor: 6.799

10.  Single-cell sequencing provides clues about the host interactions of segmented filamentous bacteria (SFB).

Authors:  Sünje J Pamp; Eoghan D Harrington; Stephen R Quake; David A Relman; Paul C Blainey
Journal:  Genome Res       Date:  2012-03-20       Impact factor: 9.043

View more
  22 in total

1.  A nanoliter microfluidic serial dilution bioreactor.

Authors:  Guo-Yue Gu; Yi-Wei Lee; Chih-Chung Chiang; Ya-Tang Yang
Journal:  Biomicrofluidics       Date:  2015-08-31       Impact factor: 2.800

2.  A valve-less microfluidic peristaltic pumping method.

Authors:  Xiannian Zhang; Zitian Chen; Yanyi Huang
Journal:  Biomicrofluidics       Date:  2015-02-11       Impact factor: 2.800

3.  Continuous flowing micro-reactor for aqueous reaction at temperature higher than 100 °C.

Authors:  Fei Xie; Baojun Wang; Wei Wang; Tian Dong; Jianhua Tong; Shanhong Xia; Wengang Wu; Zhihong Li
Journal:  Biomicrofluidics       Date:  2013-05-21       Impact factor: 2.800

4.  Microfluidic single-cell whole-transcriptome sequencing.

Authors:  Aaron M Streets; Xiannian Zhang; Chen Cao; Yuhong Pang; Xinglong Wu; Liang Xiong; Lu Yang; Yusi Fu; Liang Zhao; Fuchou Tang; Yanyi Huang
Journal:  Proc Natl Acad Sci U S A       Date:  2014-04-29       Impact factor: 11.205

5.  Current state of the art in rapid diagnostics for antimicrobial resistance.

Authors:  Rathina Kumar Shanmugakani; Balaji Srinivasan; Marshall J Glesby; Lars F Westblade; Washington B Cárdenas; Tony Raj; David Erickson; Saurabh Mehta
Journal:  Lab Chip       Date:  2020-07-09       Impact factor: 6.799

6.  Single cell transcriptomics reveals unanticipated features of early hematopoietic precursors.

Authors:  Jennifer Yang; Yoshiaki Tanaka; Montrell Seay; Zhen Li; Jiaqi Jin; Lana Xia Garmire; Xun Zhu; Ashley Taylor; Weidong Li; Ghia Euskirchen; Stephanie Halene; Yuval Kluger; Michael P Snyder; In-Hyun Park; Xinghua Pan; Sherman Morton Weissman
Journal:  Nucleic Acids Res       Date:  2017-02-17       Impact factor: 16.971

Review 7.  A review on wax printed microfluidic paper-based devices for international health.

Authors:  S Altundemir; A K Uguz; K Ulgen
Journal:  Biomicrofluidics       Date:  2017-08-30       Impact factor: 2.800

8.  Microfluidics: A new tool for modeling cancer-immune interactions.

Authors:  Alexandra Boussommier-Calleja; Ran Li; Michelle B Chen; Siew Cheng Wong; Roger D Kamm
Journal:  Trends Cancer       Date:  2016-01-01

Review 9.  Point-of-care microfluidic devices for pathogen detection.

Authors:  Behzad Nasseri; Neda Soleimani; Navid Rabiee; Alireza Kalbasi; Mahdi Karimi; Michael R Hamblin
Journal:  Biosens Bioelectron       Date:  2018-05-29       Impact factor: 10.618

10.  An Integrated Microfluidic Platform for Quantifying Drug Permeation across Biomimetic Vesicle Membranes.

Authors:  Michael Schaich; Jehangir Cama; Kareem Al Nahas; Diana Sobota; Hannah Sleath; Kevin Jahnke; Siddharth Deshpande; Cees Dekker; Ulrich F Keyser
Journal:  Mol Pharm       Date:  2019-04-29       Impact factor: 4.939

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.