Literature DB >> 2181288

Sp1 can displace GHF-1 from its distal binding site and stimulate transcription from the growth hormone gene promoter.

F P Lemaigre1, D A Lafontaine, S J Courtois, S M Durviaux, G G Rousseau.   

Abstract

DNase I footprinting experiments showed that binding activities of Sp1 and of GHF-1 to its distal site on the human growth hormone gene promoter are mutually exclusive. The kinetics of GHF-1 binding were indicative of positive cooperativity. The Sp1 site did not affect promoter activity in cell-free transcription. Still, Sp1 could compensate partially for the decreased stimulation of transcription seen at low GHF-1 concentrations.

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Year:  1990        PMID： 2181288      PMCID： PMC362291          DOI： 10.1128/mcb.10.4.1811-1814.1990

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  10 in total

1.  Evidence that the upstream stimulatory factor and the Sp1 transcription factor bind in vitro to the promoter of the human-growth-hormone gene.

Authors:  F P Lemaigre; S J Courtois; D A Lafontaine; G G Rousseau
Journal:  Eur J Biochem       Date:  1989-05-15

2.  The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein.

Authors:  M Bodner; J L Castrillo; L E Theill; T Deerinck; M Ellisman; M Karin
Journal:  Cell       Date:  1988-11-04       Impact factor: 41.582

3.  Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter.

Authors:  A Barberis; G Superti-Furga; M Busslinger
Journal:  Cell       Date:  1987-07-31       Impact factor: 41.582

4.  Reconstitution of cell-type-specific transcription of the rat prolactin gene in vitro.

Authors:  Z D Cao; E A Barron; A J Carillo; Z D Sharp
Journal:  Mol Cell Biol       Date:  1987-10       Impact factor: 4.272

5.  The interplay of DNA-binding proteins on the promoter of the mouse albumin gene.

Authors:  S Lichtsteiner; J Wuarin; U Schibler
Journal:  Cell       Date:  1987-12-24       Impact factor: 41.582

6.  A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype.

Authors:  H A Ingraham; R P Chen; H J Mangalam; H P Elsholtz; S E Flynn; C R Lin; D M Simmons; L Swanson; M G Rosenfeld
Journal:  Cell       Date:  1988-11-04       Impact factor: 41.582

7.  Comparison of experimental binding data and theoretical models in proteins containing subunits.

Authors:  D E Koshland; G Némethy; D Filmer
Journal:  Biochemistry       Date:  1966-01       Impact factor: 3.162

8.  Pituitary-specific factor binding to the human prolactin, growth hormone, and placental lactogen genes.

Authors:  F P Lemaigre; B Peers; D A Lafontaine; M Mathy-Hartert; G G Rousseau; A Belayew; J A Martial
Journal:  DNA       Date:  1989-04

9.  Transcription factors AP-3 and AP-2 interact with the SV40 enhancer in a mutually exclusive manner.

Authors:  F Mercurio; M Karin
Journal:  EMBO J       Date:  1989-05       Impact factor: 11.598

10.  Tissue-specific expression of the human growth hormone gene is conferred in part by the binding of a specific trans-acting factor.

Authors:  C Lefevre; M Imagawa; S Dana; J Grindlay; M Bodner; M Karin
Journal:  EMBO J       Date:  1987-04       Impact factor: 11.598
  10 in total
  12 in total

1.  Elements in the first intron of the alpha 1(I) collagen gene interact with Sp1 to regulate gene expression.

Authors:  D J Liska; V R Robinson; P Bornstein
Journal:  Gene Expr       Date:  1992

2.  Compilation of vertebrate-encoded transcription factors.

Authors:  S Faisst; S Meyer
Journal:  Nucleic Acids Res       Date:  1992-01-11       Impact factor: 16.971

3.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1990-08-25       Impact factor: 16.971

4.  ZBP-89, a Krüppel-like zinc finger protein, inhibits epidermal growth factor induction of the gastrin promoter.

Authors:  J L Merchant; G R Iyer; B R Taylor; J R Kitchen; E R Mortensen; Z Wang; R J Flintoft; J B Michel; R Bassel-Duby
Journal:  Mol Cell Biol       Date:  1996-12       Impact factor: 4.272

5.  A compilation of composite regulatory elements affecting gene transcription in vertebrates.

Authors:  O V Kel; A G Romaschenko; A E Kel; E Wingender; N A Kolchanov
Journal:  Nucleic Acids Res       Date:  1995-10-25       Impact factor: 16.971

6.  The E6/E7 promoter of human papillomavirus type 16 is activated in the absence of E2 proteins by a sequence-aberrant Sp1 distal element.

Authors:  B Gloss; H U Bernard
Journal:  J Virol       Date:  1990-11       Impact factor: 5.103

7.  Hepatocyte nuclear factor-6 stimulates transcription of the alpha-fetoprotein gene and synergizes with the retinoic-acid-receptor-related orphan receptor alpha-4.

Authors:  Habib Nacer-Cherif; Brigitte Bois-Joyeux; Guy G Rousseau; Frédéric P Lemaigre; Jean-Louis Danan
Journal:  Biochem J       Date:  2003-02-01       Impact factor: 3.857

Review 8.  Molecular basis of etiological implications in Alzheimer's disease: focus on neuroinflammation.

Authors:  Rituraj Niranjan
Journal:  Mol Neurobiol       Date:  2013-02-19       Impact factor: 5.590

9.  Analysis of human growth hormone gene 5' sequences in isolated growth hormone deficiency patients.

Authors:  Y Wang; L L Yu; Q Sheng; C Meng; J Sun; S S Chen
Journal:  J Med Genet       Date:  1994-01       Impact factor: 6.318

10.  Participation of Ets transcription factors in the glucocorticoid response of the rat tyrosine aminotransferase gene.

Authors:  M L Espinás; J Roux; J Ghysdael; R Pictet; T Grange
Journal:  Mol Cell Biol       Date:  1994-06       Impact factor: 4.272
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