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Literature DB >> 21799494

Protein engineering: navigating between chance and reason.

Monya Baker¹.
1. m.baker@us.nature.com

Abstract

Mesh：

Substances：
Peptide Library

Year: 2011 PMID： 21799494 DOI： 10.1038/nmeth.1654

Source DB: PubMed Journal: Nat Methods ISSN： 1548-7091 Impact factor: 28.547

× No keyword cloud information.

8 in total

Review 1. Biocatalysts by evolution.

Authors: Christian Jäckel; Donald Hilvert
Journal: Curr Opin Biotechnol Date: 2010-09-17 Impact factor: 9.740

Review 2. Laboratory evolution of stereoselective enzymes: a prolific source of catalysts for asymmetric reactions.

Authors: Manfred T Reetz
Journal: Angew Chem Int Ed Engl Date: 2011-01-03 Impact factor: 15.336

3. Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction.

Authors: Justin B Siegel; Alexandre Zanghellini; Helena M Lovick; Gert Kiss; Abigail R Lambert; Jennifer L St Clair; Jasmine L Gallaher; Donald Hilvert; Michael H Gelb; Barry L Stoddard; Kendall N Houk; Forrest E Michael; David Baker
Journal: Science Date: 2010-07-16 Impact factor: 47.728

4. A general strategy for the evolution of bond-forming enzymes using yeast display.

Authors: Irwin Chen; Brent M Dorr; David R Liu
Journal: Proc Natl Acad Sci U S A Date: 2011-06-22 Impact factor: 11.205

5. Computational design of proteins targeting the conserved stem region of influenza hemagglutinin.

Authors: Sarel J Fleishman; Timothy A Whitehead; Damian C Ekiert; Cyrille Dreyfus; Jacob E Corn; Eva-Maria Strauch; Ian A Wilson; David Baker
Journal: Science Date: 2011-05-13 Impact factor: 47.728

6. Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.

Authors: Y Chen; C Wiesmann; G Fuh; B Li; H W Christinger; P McKay; A M de Vos; H B Lowman
Journal: J Mol Biol Date: 1999-11-05 Impact factor: 5.469

7. Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture.

Authors: Christopher K Savile; Jacob M Janey; Emily C Mundorff; Jeffrey C Moore; Sarena Tam; William R Jarvis; Jeffrey C Colbeck; Anke Krebber; Fred J Fleitz; Jos Brands; Paul N Devine; Gjalt W Huisman; Gregory J Hughes
Journal: Science Date: 2010-06-17 Impact factor: 47.728

8. A system for the continuous directed evolution of biomolecules.

Authors: Kevin M Esvelt; Jacob C Carlson; David R Liu
Journal: Nature Date: 2011-04-10 Impact factor: 49.962

8 in total

5 in total

Protein engineering: navigating between chance and reason.

Review 1. Biocatalysts by evolution.

Review 2. Laboratory evolution of stereoselective enzymes: a prolific source of catalysts for asymmetric reactions.

3. Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction.

4. A general strategy for the evolution of bond-forming enzymes using yeast display.

5. Computational design of proteins targeting the conserved stem region of influenza hemagglutinin.

6. Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.

7. Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture.

8. A system for the continuous directed evolution of biomolecules.

Review 1. Genetically modified proteins: functional improvement and chimeragenesis.

Review 2. The Structural and Functional Diversity of Intrinsically Disordered Regions in Transmembrane Proteins.

3. Rational design of a colorimetric pH sensor from a soluble retinoic acid chaperone.

4. Rational engineering of enzyme allosteric regulation through sequence evolution analysis.

Review 5. Nanobodies: Chemical Functionalization Strategies and Intracellular Applications.