PURPOSE: To present the long-term results after simultaneous photorefractive keratectomy followed by corneal collagen cross-linking for keratoconus. DESIGN: Prospective, interventional, consecutive case series. METHODS: In this study, 26 patients (31 eyes) with progressive keratoconus were included. All patients underwent customized topography-guided photorefractive keratectomy immediately followed by corneal collagen cross-linking with the use of riboflavin and ultraviolet A irradiation. Epithelium was removed by transepithelial phototherapeutic keratectomy in all cases. RESULTS: Mean follow-up was 19.53 ± 3.97 months (range, 12 to 25 months). Mean preoperative spherical equivalent was -2.3 ± 2.8 diopters (D), whereas at the last follow-up examination, it was significantly (P < .001) reduced to -1.08 ± 2.41 D. Logarithm of the minimal angle of resolution uncorrected and best-corrected visual acuity were reduced significantly by 0.46 and 0.084 (P < .001), respectively, at the last follow-up examination. Finally, mean steep and flat keratometry readings were reduced by 2.35 (P < .001) and 1.18 (P = .013) at the last follow-up examination. CONCLUSIONS: Simultaneous photorefractive keratectomy followed by corneal collagen cross-linking seems to be a promising treatment alternative in our series of keratoconic patients.
PURPOSE: To present the long-term results after simultaneous photorefractive keratectomy followed by corneal collagen cross-linking for keratoconus. DESIGN: Prospective, interventional, consecutive case series. METHODS: In this study, 26 patients (31 eyes) with progressive keratoconus were included. All patients underwent customized topography-guided photorefractive keratectomy immediately followed by corneal collagen cross-linking with the use of riboflavin and ultraviolet A irradiation. Epithelium was removed by transepithelial phototherapeutic keratectomy in all cases. RESULTS: Mean follow-up was 19.53 ± 3.97 months (range, 12 to 25 months). Mean preoperative spherical equivalent was -2.3 ± 2.8 diopters (D), whereas at the last follow-up examination, it was significantly (P < .001) reduced to -1.08 ± 2.41 D. Logarithm of the minimal angle of resolution uncorrected and best-corrected visual acuity were reduced significantly by 0.46 and 0.084 (P < .001), respectively, at the last follow-up examination. Finally, mean steep and flat keratometry readings were reduced by 2.35 (P < .001) and 1.18 (P = .013) at the last follow-up examination. CONCLUSIONS: Simultaneous photorefractive keratectomy followed by corneal collagen cross-linking seems to be a promising treatment alternative in our series of keratoconic patients.
Authors: Sana Niazi; Jorge Alio Del Barrio; Azad Sanginabadi; Farideh Doroodgar; Cyrus Alinia; Alireza Baradaran-Rafii; Feaizollah Niazi; Hossein Mohammad-Rabei; Mohammad Mehdi Sadoughi; Jorge L Alio Journal: Int J Ophthalmol Date: 2022-05-18 Impact factor: 1.779
Authors: Rafic Antonios; Ali Dirani; Ali Fadlallah; Elias Chelala; Adib Hamade; Carole Cherfane; Elias Jarade Journal: J Ophthalmol Date: 2015-03-19 Impact factor: 1.909