Literature DB >> 21792191

An overlooked neurotoxic species in Alzheimer's disease.

Iryna Benilova1, Bart De Strooper.   

Abstract

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Year:  2011        PMID： 21792191     DOI： 10.1038/nn.2871

Source DB:  PubMed          Journal:  Nat Neurosci        ISSN： 1097-6256            Impact factor:   24.884


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  15 in total

1.  Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration.

Authors:  Ming Jin; Nina Shepardson; Ting Yang; Gang Chen; Dominic Walsh; Dennis J Selkoe
Journal:  Proc Natl Acad Sci U S A       Date:  2011-03-18       Impact factor: 11.205

2.  Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms.

Authors:  Mostafa Bentahir; Omar Nyabi; Jan Verhamme; Alexandra Tolia; Katrien Horré; Jens Wiltfang; Hermann Esselmann; Bart De Strooper
Journal:  J Neurochem       Date:  2006-01-09       Impact factor: 5.372

Review 3.  The amyloid hypothesis for Alzheimer's disease: a critical reappraisal.

Authors:  John Hardy
Journal:  J Neurochem       Date:  2009-05-18       Impact factor: 5.372

4.  Potent amyloidogenicity and pathogenicity of Aβ43.

Authors:  Takashi Saito; Takahiro Suemoto; Nathalie Brouwers; Kristel Sleegers; Satoru Funamoto; Naomi Mihira; Yukio Matsuba; Kazuyuki Yamada; Per Nilsson; Jiro Takano; Masaki Nishimura; Nobuhisa Iwata; Christine Van Broeckhoven; Yasuo Ihara; Takaomi C Saido
Journal:  Nat Neurosci       Date:  2011-07-03       Impact factor: 24.884

Review 5.  Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease.

Authors:  Bart De Strooper
Journal:  EMBO Rep       Date:  2007-02       Impact factor: 8.807

6.  Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase.

Authors:  Yue Qi-Takahara; Maho Morishima-Kawashima; Yu Tanimura; Georgia Dolios; Naoko Hirotani; Yuko Horikoshi; Fuyuki Kametani; Masahiro Maeda; Takaomi C Saido; Rong Wang; Yasuo Ihara
Journal:  J Neurosci       Date:  2005-01-12       Impact factor: 6.167

Review 7.  The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.

Authors:  John Hardy; Dennis J Selkoe
Journal:  Science       Date:  2002-07-19       Impact factor: 47.728

8.  Abeta43 is more frequent than Abeta40 in amyloid plaque cores from Alzheimer disease brains.

Authors:  Hedvig Welander; Jenny Frånberg; Caroline Graff; Erik Sundström; Bengt Winblad; Lars O Tjernberg
Journal:  J Neurochem       Date:  2009-05-15       Impact factor: 5.372

9.  Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence.

Authors:  B De Strooper; M Simons; G Multhaup; F Van Leuven; K Beyreuther; C G Dotti
Journal:  EMBO J       Date:  1995-10-16       Impact factor: 11.598

10.  Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice.

Authors:  Ivo Cristiano Martins; Inna Kuperstein; Hannah Wilkinson; Elke Maes; Mieke Vanbrabant; Wim Jonckheere; Patrick Van Gelder; Dieter Hartmann; Rudi D'Hooge; Bart De Strooper; Joost Schymkowitz; Frederic Rousseau
Journal:  EMBO J       Date:  2007-12-06       Impact factor: 11.598
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  8 in total

1.  Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation.

Authors:  Axel Abelein; Astrid Gräslund; Jens Danielsson
Journal:  Proc Natl Acad Sci U S A       Date:  2015-03-30       Impact factor: 11.205

2.  Memantine rescues transient cognitive impairment caused by high-molecular-weight aβ oligomers but not the persistent impairment induced by low-molecular-weight oligomers.

Authors:  Cláudia P Figueiredo; Julia R Clarke; José Henrique Ledo; Felipe C Ribeiro; Carine V Costa; Helen M Melo; Axa P Mota-Sales; Leonardo M Saraiva; William L Klein; Adriano Sebollela; Fernanda G De Felice; Sergio T Ferreira
Journal:  J Neurosci       Date:  2013-06-05       Impact factor: 6.167

3.  Modulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's disease.

Authors:  Zeljko M Svedružić; Katarina Popović; Ivana Smoljan; Vesna Sendula-Jengić
Journal:  PLoS One       Date:  2012-03-30       Impact factor: 3.240

4.  Elucidating molecular mass and shape of a neurotoxic Aβ oligomer.

Authors:  Adriano Sebollela; Gina-Mirela Mustata; Kevin Luo; Pauline T Velasco; Kirsten L Viola; Erika N Cline; Gajendra S Shekhawat; Kyle C Wilcox; Vinayak P Dravid; William L Klein
Journal:  ACS Chem Neurosci       Date:  2014-11-07       Impact factor: 4.418

Review 5.  Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's disease.

Authors:  Sergio T Ferreira; Mychael V Lourenco; Mauricio M Oliveira; Fernanda G De Felice
Journal:  Front Cell Neurosci       Date:  2015-05-26       Impact factor: 5.505

Review 6.  Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's disease.

Authors:  Gary P Morris; Ian A Clark; Bryce Vissel
Journal:  Acta Neuropathol Commun       Date:  2014-09-18       Impact factor: 7.801

Review 7.  Recent Advances in the Inhibition of p38 MAPK as a Potential Strategy for the Treatment of Alzheimer's Disease.

Authors:  Jong Kil Lee; Nam-Jung Kim
Journal:  Molecules       Date:  2017-08-02       Impact factor: 4.411

8.  Modulators of γ-secretase activity can facilitate the toxic side-effects and pathogenesis of Alzheimer's disease.

Authors:  Željko M Svedružić; Katarina Popović; Vesna Šendula-Jengić
Journal:  PLoS One       Date:  2013-01-07       Impact factor: 3.240
  8 in total

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