Literature DB >> 21779608

Non-hemolytic α-AApeptides as antimicrobial peptidomimetics.

Shruti Padhee1, Yaogang Hu, Youhong Niu, Ge Bai, Haifan Wu, Frankie Costanza, Leigh West, Lacey Harrington, Lindsey N Shaw, Chuanhai Cao, Jianfeng Cai.   

Abstract

We report a new class of peptide mimetics, α-AApeptides, that display broad-spectrum activity against both Gram-negative and Gram-positive bacteria and fungi. With non-hemolytic activity, resistance to protease hydrolysis, and easy sequence programmability, α-AApeptides may emerge as a novel class of antibiotics. This journal is © The Royal Society of Chemistry 2011

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Year:  2011        PMID： 21779608     DOI： 10.1039/c1cc13684d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  22 in total

1.  Polycarbonates with Potent and Selective Antimicrobial Activity toward Gram-Positive Bacteria.

Authors:  Alekhya Nimmagadda; Xuan Liu; Peng Teng; Ma Su; Yaqiong Li; Qiao Qiao; Nawal K Khadka; Xiaoting Sun; Jianjun Pan; Hai Xu; Qi Li; Jianfeng Cai
Journal:  Biomacromolecules       Date:  2016-12-08       Impact factor: 6.988

2.  The development of antimicrobial a-AApeptides that suppress proinflammatory immune responses.

Authors:  Shruti Padhee; Christina Smith; Haifan Wu; Yaqiong Li; Namitha Manoj; Qiao Qiao; Zoya Khan; Chuanhai Cao; Hang Yin; Jianfeng Cai
Journal:  Chembiochem       Date:  2014-03-21       Impact factor: 3.164

3.  Lipidated peptidomimetics with improved antimicrobial activity.

Authors:  Yaogang Hu; Mohamad Nassir Amin; Shruti Padhee; Rongsheng E Wang; Qiao Qiao; Ge Bai; Yaqong Li; Archana Mathew; Chuanhai Cao; Jianfeng Cai
Journal:  ACS Med Chem Lett       Date:  2012-07-12       Impact factor: 4.345

Review 4.  The development of antimicrobial γ-AApeptides.

Authors:  Fengyu She; Olapeju Oyesiku; Peiguang Zhou; Shiming Zhuang; David W Koenig; Jianfeng Cai
Journal:  Future Med Chem       Date:  2016-06-10       Impact factor: 3.808

Review 5.  Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs.

Authors:  Natalia Molchanova; Paul R Hansen; Henrik Franzyk
Journal:  Molecules       Date:  2017-08-29       Impact factor: 4.411

6.  Identification of γ-AApeptides with potent and broad-spectrum antimicrobial activity.

Authors:  Youhong Niu; Shruti Padhee; Haifan Wu; Ge Bai; Lacey Harrington; Whittney N Burda; Lindsey N Shaw; Chuanhai Cao; Jianfeng Cai
Journal:  Chem Commun (Camb)       Date:  2011-10-03       Impact factor: 6.222

Review 7.  Antimicrobial AApeptides.

Authors:  Peng Sang; Yan Shi; Peng Teng; Annie Cao; Hai Xu; Qi Li; Jianfeng Cai
Journal:  Curr Top Med Chem       Date:  2017       Impact factor: 3.295

8.  Small lipopeptides possess anti-biofilm capability comparable to daptomycin and vancomycin.

Authors:  Biswajit Mishra; Tamara Lushnikova; Guangshun Wang
Journal:  RSC Adv       Date:  2015       Impact factor: 3.361

9.  Short antimicrobial lipo-α/γ-AA hybrid peptides.

Authors:  Yaqiong Li; Christina Smith; Haifan Wu; Peng Teng; Yan Shi; Shruti Padhee; Torey Jones; Anh-My Nguyen; Chuanhai Cao; Hang Yin; Jianfeng Cai
Journal:  Chembiochem       Date:  2014-08-28       Impact factor: 3.164

10.  Helical 1:1 α/Sulfono-γ-AA Heterogeneous Peptides with Antibacterial Activity.

Authors:  Fengyu She; Alekhya Nimmagadda; Peng Teng; Ma Su; Xiaobing Zuo; Jianfeng Cai
Journal:  Biomacromolecules       Date:  2016-04-13       Impact factor: 6.988
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