The synthesis of new 2+2 metalla-rectangles via coordination driven self-assembly of octahedral Ru(II) based acceptors and amide donors is described. To evaluate their in vitro cytotoxic properties, preliminary biological assays were carried out for various human cancer cell lines, and our results show that the cytotoxicity level of 3 is comparable or even greater in the cases of SK-hep-1 and HCT-15 than that of the reference drug cisplatin.
The synthesis of new 2+2 metalla-rectangles via coordination driven self-assembly of octahedral n class="Chemical">Ru(II) based acceptors and amidedonors is described. To evaluate their in vitro cytotoxic properties, preliminary biological assays were carried out for various humancancer cell lines, and our results show that the cytotoxicity level of 3 is comparable or even greater in the cases of SK-hep-1 and HCT-15 than that of the reference drug cisplatin.
Authors: Koushik Ghosh; Jiming Hu; Hai-Bo Yang; Brian H Northrop; Henry S White; Peter J Stang Journal: J Org Chem Date: 2009-07-03 Impact factor: 4.354
Authors: Fátima Linares; Miguel A Galindo; Simona Galli; M Angustias Romero; Jorge A R Navarro; Elisa Barea Journal: Inorg Chem Date: 2009-08-03 Impact factor: 5.165
Authors: Vaishali Vajpayee; Young Ho Song; Young Jun Jung; Se Chan Kang; Hyunuk Kim; In Su Kim; Ming Wang; Timothy R Cook; Peter J Stang; Ki-Whan Chi Journal: Dalton Trans Date: 2012-01-26 Impact factor: 4.390
Authors: Vaishali Vajpayee; Young Ho Song; Yoon Jung Yang; Se Chan Kang; Timothy R Cook; Dong Wook Kim; Myoung Soo Lah; In Su Kim; Ming Wang; Peter J Stang; Ki-Whan Chi Journal: Organometallics Date: 2011-12-12 Impact factor: 3.876
Authors: Vaishali Vajpayee; Young Ho Song; Timothy R Cook; Hyunuk Kim; Youngil Lee; Peter J Stang; Ki-Whan Chi Journal: J Am Chem Soc Date: 2011-11-15 Impact factor: 15.419
Authors: Floyd A Beckford; Madison B Niece; Brittany P Lassiter; Stephen J Beebe; Alvin A Holder Journal: J Biol Inorg Chem Date: 2018-07-23 Impact factor: 3.358