Literature DB >> 21779140

Coordination Driven Self-Assembly and Anticancer Activity of Molecular Rectangles Containing Octahedral Ruthenium Metal Centers.

Vaishali Vajpayee1, Young Ho Song, Yoon Jung Yang, Se Chan Kang, Hyunuk Kim, In Su Kim, Ming Wang, Peter J Stang, Ki-Whan Chi.   

Abstract

The synthesis of new 2+2 metalla-rectangles via coordination driven self-assembly of octahedral Ru(II) based acceptors and amide donors is described. To evaluate their in vitro cytotoxic properties, preliminary biological assays were carried out for various human cancer cell lines, and our results show that the cytotoxicity level of 3 is comparable or even greater in the cases of SK-hep-1 and HCT-15 than that of the reference drug cisplatin.

Entities:  

Year:  2011        PMID： 21779140      PMCID： PMC3138154          DOI： 10.1021/om200294x

Source DB:  PubMed          Journal:  Organometallics        ISSN： 0276-7333            Impact factor:   3.876


  38 in total

Review 1.  The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting.

Authors:  H Maeda
Journal:  Adv Enzyme Regul       Date:  2001

2.  Selective molecular recognition, C-H bond activation, and catalysis in nanoscale reaction vessels.

Authors:  Dorothea Fiedler; Dennis H Leung; Robert G Bergman; Kenneth N Raymond
Journal:  Acc Chem Res       Date:  2005-04       Impact factor: 22.384

3.  Evidence for drug release from a metalla-cage delivery vector following cellular internalisation.

Authors:  Olivier Zava; Johan Mattsson; Bruno Therrien; Paul J Dyson
Journal:  Chemistry       Date:  2010-02-01       Impact factor: 5.236

Review 4.  Metal-based antitumour drugs in the post genomic era.

Authors:  Paul J Dyson; Gianni Sava
Journal:  Dalton Trans       Date:  2006-03-28       Impact factor: 4.390

5.  Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging.

Authors:  D A Tomalia; L A Reyna; S Svenson
Journal:  Biochem Soc Trans       Date:  2007-02       Impact factor: 5.407

Review 6.  Ligand based dendritic systems for tumor targeting.

Authors:  Abhinav Agarwal; Surbhi Saraf; Abhay Asthana; Umesh Gupta; Virendra Gajbhiye; Narendra K Jain
Journal:  Int J Pharm       Date:  2007-09-25       Impact factor: 5.875

Review 7.  Therapeutic and diagnostic applications of dendrimers for cancer treatment.

Authors:  Jesse B Wolinsky; Mark W Grinstaff
Journal:  Adv Drug Deliv Rev       Date:  2008-03-04       Impact factor: 15.470

8.  Introduction of heterofunctional groups onto molecular hexagons via coordination-driven self-assembly.

Authors:  Koushik Ghosh; Jiming Hu; Hai-Bo Yang; Brian H Northrop; Henry S White; Peter J Stang
Journal:  J Org Chem       Date:  2009-07-03       Impact factor: 4.354

9.  Tetranuclear coordination assemblies based on half-sandwich ruthenium(II) complexes: noncovalent binding to DNA and cytotoxicity.

Authors:  Fátima Linares; Miguel A Galindo; Simona Galli; M Angustias Romero; Jorge A R Navarro; Elisa Barea
Journal:  Inorg Chem       Date:  2009-08-03       Impact factor: 5.165

10.  A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Authors:  Y Matsumura; H Maeda
Journal:  Cancer Res       Date:  1986-12       Impact factor: 12.701
View more
  11 in total

1.  Coordination-driven self-assembly of ruthenium-based molecular-rectangles: synthesis, characterization, photo-physical and anticancer potency studies.

Authors:  Vaishali Vajpayee; Young Ho Song; Young Jun Jung; Se Chan Kang; Hyunuk Kim; In Su Kim; Ming Wang; Timothy R Cook; Peter J Stang; Ki-Whan Chi
Journal:  Dalton Trans       Date:  2012-01-26       Impact factor: 4.390

Review 2.  Supramolecular coordination: self-assembly of finite two- and three-dimensional ensembles.

Authors:  Rajesh Chakrabarty; Partha Sarathi Mukherjee; Peter J Stang
Journal:  Chem Rev       Date:  2011-08-24       Impact factor: 60.622

3.  Biomedical Applications of Metal Organic Polygons and Polyhedra (MOPs).

Authors:  Soumen K Samanta; Lyle Isaacs
Journal:  Coord Chem Rev       Date:  2020-02-19       Impact factor: 22.315

4.  Self-assembly of Cationic, Hetero- or Homo-nuclear Ru(II) Macrocyclic Rectangles and their Photophysical, Electrochemical and Biological Studies.

Authors:  Vaishali Vajpayee; Young Ho Song; Yoon Jung Yang; Se Chan Kang; Timothy R Cook; Dong Wook Kim; Myoung Soo Lah; In Su Kim; Ming Wang; Peter J Stang; Ki-Whan Chi
Journal:  Organometallics       Date:  2011-12-12       Impact factor: 3.876

5.  A unique non-catenane interlocked self-assembled supramolecular architecture and its photophysical properties.

Authors:  Vaishali Vajpayee; Young Ho Song; Timothy R Cook; Hyunuk Kim; Youngil Lee; Peter J Stang; Ki-Whan Chi
Journal:  J Am Chem Soc       Date:  2011-11-15       Impact factor: 15.419

6.  Anticancer Activity of Self-Assembled Molecular Rectangles via Arene-Ruthenium Acceptors and a New Unsymmetrical Amide Ligand.

Authors:  Anurag Mishra; Hyunji Jung; Jeong Woo Park; Hong Kyeung Kim; Hyunuk Kim; Peter J Stang; Ki-Whan Chi
Journal:  Organometallics       Date:  2012-04-13       Impact factor: 3.876

7.  Interaction of a ruthenium hexacationic prism with amino acids and biological ligands: ESI mass spectrometry and NMR characterisation of the reaction products.

Authors:  Lydia E H Paul; Bruno Therrien; Julien Furrer
Journal:  J Biol Inorg Chem       Date:  2012-07-06       Impact factor: 3.358

8.  Polynuclear ruthenium organometallic complexes containing a 1,3,5-triazine ligand: synthesis, DNA interaction, and biological activity.

Authors:  Floyd A Beckford; Madison B Niece; Brittany P Lassiter; Stephen J Beebe; Alvin A Holder
Journal:  J Biol Inorg Chem       Date:  2018-07-23       Impact factor: 3.358

Review 9.  Metal-organic frameworks and self-assembled supramolecular coordination complexes: comparing and contrasting the design, synthesis, and functionality of metal-organic materials.

Authors:  Timothy R Cook; Yao-Rong Zheng; Peter J Stang
Journal:  Chem Rev       Date:  2012-11-02       Impact factor: 60.622

10.  Biomedical and biochemical applications of self-assembled metallacycles and metallacages.

Authors:  Timothy R Cook; Vaishali Vajpayee; Min Hyung Lee; Peter J Stang; Ki-Whan Chi
Journal:  Acc Chem Res       Date:  2013-06-20       Impact factor: 22.384
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.