Literature DB >> 32255835

Biomedical Applications of Metal Organic Polygons and Polyhedra (MOPs).

Soumen K Samanta1,2, Lyle Isaacs1.   

Abstract

Since the discovery and structural characterization of metal organic polygons and polyhedra (MOPs), scientists have explored their potential in various applications like catalysis, separation, storage, and sensing. In recent years, scientists have explored the potential of supramolecular MOPs in biomedical application. Pioneering works by Ehrlich, Rosenberg, Lippard, Stang and others have demonstrated that MOPs have great potential as a novel class of metallo-therapeutics that can deliver cargoes (drugs and dyes) selectively. In this article, we document the progress made over the past two decades on the biomedical applications of MOPs and discuss the future prospects of this emerging field.

Entities:  

Keywords:  Antitumor Agents; Drug Delivery; Drug Formulation; MOPs; Metallotherapeutics

Year:  2020        PMID: 32255835      PMCID: PMC7108793          DOI: 10.1016/j.ccr.2020.213181

Source DB:  PubMed          Journal:  Coord Chem Rev        ISSN: 0010-8545            Impact factor:   22.315


  102 in total

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Journal:  Adv Mater       Date:  2011-01-04       Impact factor: 30.849

2.  Metal-organic frameworks as efficient materials for drug delivery.

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Journal:  Angew Chem Int Ed Engl       Date:  2006-09-11       Impact factor: 15.336

Review 3.  Direct cellular responses to platinum-induced DNA damage.

Authors:  Yongwon Jung; Stephen J Lippard
Journal:  Chem Rev       Date:  2007-04-25       Impact factor: 60.622

4.  The "complex-in-a-complex" cations [(acac)2M subset Ru6(p-iPrC6H4Me)6(tpt)2(dhbq)3]6+: A trojan horse for cancer cells.

Authors:  Bruno Therrien; Georg Süss-Fink; Padavattan Govindaswamy; Anna K Renfrew; Paul J Dyson
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

5.  Cucurbit[7]uril Enables Multi-Stimuli-Responsive Release from the Self-Assembled Hydrophobic Phase of a Metal Organic Polyhedron.

Authors:  Soumen K Samanta; Jeffrey Quigley; Brittany Vinciguerra; Volker Briken; Lyle Isaacs
Journal:  J Am Chem Soc       Date:  2017-06-23       Impact factor: 15.419

Review 6.  Principles in the design of ligand-targeted cancer therapeutics and imaging agents.

Authors:  Madduri Srinivasarao; Chris V Galliford; Philip S Low
Journal:  Nat Rev Drug Discov       Date:  2015-02-20       Impact factor: 84.694

7.  Coordination Driven Self-Assembly and Anticancer Activity of Molecular Rectangles Containing Octahedral Ruthenium Metal Centers.

Authors:  Vaishali Vajpayee; Young Ho Song; Yoon Jung Yang; Se Chan Kang; Hyunuk Kim; In Su Kim; Ming Wang; Peter J Stang; Ki-Whan Chi
Journal:  Organometallics       Date:  2011-06-27       Impact factor: 3.876

Review 8.  Metal-organic frameworks and self-assembled supramolecular coordination complexes: comparing and contrasting the design, synthesis, and functionality of metal-organic materials.

Authors:  Timothy R Cook; Yao-Rong Zheng; Peter J Stang
Journal:  Chem Rev       Date:  2012-11-02       Impact factor: 60.622

9.  Biomedical and biochemical applications of self-assembled metallacycles and metallacages.

Authors:  Timothy R Cook; Vaishali Vajpayee; Min Hyung Lee; Peter J Stang; Ki-Whan Chi
Journal:  Acc Chem Res       Date:  2013-06-20       Impact factor: 22.384

Review 10.  Metal-Organic Framework-Based Stimuli-Responsive Systems for Drug Delivery.

Authors:  Wen Cai; Junqing Wang; Chengchao Chu; Wei Chen; Chunsheng Wu; Gang Liu
Journal:  Adv Sci (Weinh)       Date:  2018-11-20       Impact factor: 16.806

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  5 in total

1.  Design and Applications of Water-Soluble Coordination Cages.

Authors:  Edmundo G Percástegui; Tanya K Ronson; Jonathan R Nitschke
Journal:  Chem Rev       Date:  2020-11-25       Impact factor: 60.622

2.  Incorporation of a Phosphino(pyridine) Subcomponent Enables the Formation of Cages with Homobimetallic and Heterobimetallic Vertices.

Authors:  John P Carpenter; Tanya K Ronson; Felix J Rizzuto; Théophile Héliot; Peter Grice; Jonathan R Nitschke
Journal:  J Am Chem Soc       Date:  2022-05-05       Impact factor: 16.383

3.  Hyper-CEST NMR of metal organic polyhedral cages reveals hidden diastereomers with diverse guest exchange kinetics.

Authors:  Jabadurai Jayapaul; Sanna Komulainen; Vladimir V Zhivonitko; Jiří Mareš; Chandan Giri; Kari Rissanen; Perttu Lantto; Ville-Veikko Telkki; Leif Schröder
Journal:  Nat Commun       Date:  2022-03-31       Impact factor: 17.694

4.  Acyclic Cucurbituril Featuring Pendant Cyclodextrins.

Authors:  Ming Cheng; Lyle Isaacs
Journal:  Supramol Chem       Date:  2021-05-31       Impact factor: 1.688

5.  Cavity-Containing [Fe2L3]4+ Helicates: An Examination of Host-Guest Chemistry and Cytotoxicity.

Authors:  Lynn S Lisboa; Mie Riisom; Roan A S Vasdev; Stephen M F Jamieson; L James Wright; Christian G Hartinger; James D Crowley
Journal:  Front Chem       Date:  2021-07-07       Impact factor: 5.221

  5 in total

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