PURPOSE: To assess the effects of strenuous exercise on magnetic resonance diffusion parameters and muscle-tendon complex function in skeletal muscle. MATERIALS AND METHODS: Six men performed ankle plantar flexion exercises with eccentric contraction. The fractional anisotropy (FA), λ(1) , λ(2) , λ(3) , mean diffusivity (MD), and T(2) values in the triceps surae muscles were measured by magnetic resonance diffusion tensor and spin-echo imaging. Passive torque of plantar flexors, maximal voluntary isometric plantar flexion torques (MVIP), and Achilles tendon stiffness during MVIP were measured by combined ultrasonography and dynamometry. Plasma creatine kinase and muscle soreness were also assessed. These parameters were measured before and 1-8 days postexercise. RESULTS: The medial gastrocnemius exhibited significantly decreased FA 2-5 days after, increased λ(2) 3 days after, and increased λ(3) 2 and 3 days after exercise. This muscle also showed significantly increased MD and T(2) values 3 days postexercise. MVIP significantly decreased 2 and 3 days postexercise, while passive torque significantly increased 2 days postexercise. Creatine kinase and muscle soreness increased 3-5 days and 1-5 days postexercise, respectively. CONCLUSION: Exercise-induced muscle damage manifested as significant changes in muscle diffusion parameters with muscle-tendon complex dysfunction and delayed-onset muscle soreness.
PURPOSE: To assess the effects of strenuous exercise on magnetic resonance diffusion parameters and muscle-tendon complex function in skeletal muscle. MATERIALS AND METHODS: Six men performed ankle plantar flexion exercises with eccentric contraction. The fractional anisotropy (FA), λ(1) , λ(2) , λ(3) , mean diffusivity (MD), and T(2) values in the triceps surae muscles were measured by magnetic resonance diffusion tensor and spin-echo imaging. Passive torque of plantar flexors, maximal voluntary isometric plantar flexion torques (MVIP), and Achilles tendon stiffness during MVIP were measured by combined ultrasonography and dynamometry. Plasma creatine kinase and muscle soreness were also assessed. These parameters were measured before and 1-8 days postexercise. RESULTS: The medial gastrocnemius exhibited significantly decreased FA 2-5 days after, increased λ(2) 3 days after, and increased λ(3) 2 and 3 days after exercise. This muscle also showed significantly increased MD and T(2) values 3 days postexercise. MVIP significantly decreased 2 and 3 days postexercise, while passive torque significantly increased 2 days postexercise. Creatine kinase and muscle soreness increased 3-5 days and 1-5 days postexercise, respectively. CONCLUSION: Exercise-induced muscle damage manifested as significant changes in muscle diffusion parameters with muscle-tendon complex dysfunction and delayed-onset muscle soreness.
Authors: Eric E Sigmund; Dmitry S Novikov; Dabang Sui; Obehi Ukpebor; Steven Baete; James S Babb; Kecheng Liu; Thorsten Feiweier; Jane Kwon; Kellyanne McGorty; Jenny Bencardino; Els Fieremans Journal: NMR Biomed Date: 2014-03-09 Impact factor: 4.044
Authors: Eric E Sigmund; Dabang Sui; Obehi Ukpebor; Steven Baete; Els Fieremans; James S Babb; Michael Mechlin; Kecheng Liu; Jane Kwon; KellyAnne McGorty; Philip A Hodnett; Jenny Bencardino Journal: J Magn Reson Imaging Date: 2013-02-25 Impact factor: 4.813
Authors: Bryan Haddock; Sofie K Hansen; Ulrich Lindberg; Jakob Lindberg Nielsen; Ulrik Frandsen; Per Aagaard; Henrik B W Larsson; Charlotte Suetta Journal: J Appl Physiol (1985) Date: 2020-08-27
Authors: Jon Stavres; Jianli Wang; Christopher T Sica; Cheryl Blaha; Michael Herr; Samuel Pai; Aimee Cauffman; Jeffrey Vesek; Qing X Yang; Lawrence I Sinoway Journal: Eur J Appl Physiol Date: 2021-06-09 Impact factor: 3.078