| Literature DB >> 21768607 |
Ekaterina Voronina1, Geraldine Seydoux, Paolo Sassone-Corsi, Ippei Nagamori.
Abstract
"Germ granules" are cytoplasmic, nonmembrane-bound organelles unique to germline. Germ granules share components with the P bodies and stress granules of somatic cells, but also contain proteins and RNAs uniquely required for germ cell development. In this review, we focus on recent advances in our understanding of germ granule assembly, dynamics, and function. One hypothesis is that germ granules operate as hubs for the posttranscriptional control of gene expression, a function at the core of the germ cell differentiation program.Mesh:
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Year: 2011 PMID: 21768607 PMCID: PMC3225947 DOI: 10.1101/cshperspect.a002774
Source DB: PubMed Journal: Cold Spring Harb Perspect Biol ISSN: 1943-0264 Impact factor: 10.005