Literature DB >> 21765078

Clinical and infection control implications of Clostridium difficile infection with negative enzyme immunoassay for toxin.

Dubert M Guerrero1, Christina Chou, Lucy A Jury, Michelle M Nerandzic, Jennifer C Cadnum, Curtis J Donskey.   

Abstract

In a prospective study of 132 patients with a diagnosis of Clostridium difficile infection (CDI) by polymerase chain reaction, 43 (32%) had enzyme immunoassay (EIA) results negative for toxin. EIA-negative patients with CDI did not differ in clinical presentation from EIA-positive patients and presented a similar risk for transmission of spores.

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Year:  2011        PMID： 21765078     DOI： 10.1093/cid/cir361

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  25 in total

Review 1.  Molecular techniques for diagnosis of Clostridium difficile infection: systematic review and meta-analysis.

Authors:  John C O'Horo; Amy Jones; Matthew Sternke; Christopher Harper; Nasia Safdar
Journal:  Mayo Clin Proc       Date:  2012-07       Impact factor: 7.616

2.  Clostridium difficile PCR Cycle Threshold Predicts Free Toxin.

Authors:  Fiona Senchyna; Rajiv L Gaur; Saurabh Gombar; Cynthia Y Truong; Lee F Schroeder; Niaz Banaei
Journal:  J Clin Microbiol       Date:  2017-06-14       Impact factor: 5.948

3.  Point-Counterpoint: What Is the Optimal Approach for Detection of Clostridium difficile Infection?

Authors:  Ferric C Fang; Christopher R Polage; Mark H Wilcox
Journal:  J Clin Microbiol       Date:  2017-01-11       Impact factor: 5.948

4.  Novel portable platform for molecular detection of toxigenic Clostridium difficile in faeces: a diagnostic accuracy study.

Authors:  J J Hirvonen; P Matero; C Siebert; J Kauppila; R Vuento; H Tuokko; S Boisset
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2016-12-17       Impact factor: 3.267

Review 5.  Hospital Infection Control: Clostridioides difficile.

Authors:  Nicholas A Turner; Deverick J Anderson
Journal:  Clin Colon Rectal Surg       Date:  2020-02-25

6.  Molecular-based diagnosis of Clostridium difficile infection is associated with reduced mortality.

Authors:  Tomer Avni; Tanya Babich; Haim Ben-Zvi; Alaa Atamna; Dafna Yahav; Daniel Shepshelovich; Yaara Leibovici-Weissman; Jihad Bishara
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2018-04-07       Impact factor: 3.267

7.  Nucleic Acid Amplification Test Quantitation as Predictor of Toxin Presence in Clostridium difficile Infection.

Authors:  M J T Crobach; N Duszenko; E M Terveer; C M Verduin; E J Kuijper
Journal:  J Clin Microbiol       Date:  2018-02-22       Impact factor: 5.948

8.  Guidelines Support the Value of Stand-Alone Nucleic Acid Amplification Tests for Clostridioides (Clostridium) difficile Infection.

Authors:  Fred C Tenover; David H Persing; Ferric Fang
Journal:  J Clin Microbiol       Date:  2019-09-24       Impact factor: 5.948

Review 9.  Clostridium difficile infection: epidemiology, diagnosis and understanding transmission.

Authors:  Jessica S H Martin; Tanya M Monaghan; Mark H Wilcox
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2016-03-09       Impact factor: 46.802

10.  Outcomes in patients tested for Clostridium difficile toxins.

Authors:  Christopher R Polage; David L Chin; Jhansi L Leslie; Jevon Tang; Stuart H Cohen; Jay V Solnick
Journal:  Diagn Microbiol Infect Dis       Date:  2012-09-23       Impact factor: 2.803
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