Literature DB >> 21734722

Cancer biology and NuRD: a multifaceted chromatin remodelling complex.

Anne Y Lai1, Paul A Wade.   

Abstract

The nucleosome remodelling and histone deacetylase (NuRD; also known as Mi-2) complex regulates gene expression at the level of chromatin. The NuRD complex has been identified - using both genetic and molecular analyses - as a key determinant of differentiation in mouse embryonic stem cells and during development in various model systems. Similar to other chromatin remodellers, such as SWI/SNF and Polycomb complexes, NuRD has also been implicated in the regulation of transcriptional events that are integral to oncogenesis and cancer progression. Emerging molecular details regarding the recruitment of NuRD to specific loci during development, and the modulation of these events in cancer, are used to illustrate how the inappropriate localization of the complex could contribute to tumour biology.

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Year:  2011        PMID： 21734722      PMCID： PMC4157524          DOI： 10.1038/nrc3091

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  108 in total

1.  The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex.

Authors:  Andrea E Roche; Brett J Bassett; Sadhana A Samant; Wei Hong; Gerd A Blobel; Eric C Svensson
Journal:  J Mol Cell Cardiol       Date:  2007-11-12       Impact factor: 5.000

Review 2.  The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men.

Authors:  Xiang-Jiao Yang; Edward Seto
Journal:  Nat Rev Mol Cell Biol       Date:  2008-03       Impact factor: 94.444

3.  The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation.

Authors:  Toshimi Yoshida; Idit Hazan; Jiangwen Zhang; Samuel Y Ng; Taku Naito; Hugo J Snippert; Elizabeth J Heller; Xiaoqing Qi; Lee N Lawton; Christine J Williams; Katia Georgopoulos
Journal:  Genes Dev       Date:  2008-05-01       Impact factor: 11.361

Review 4.  The SWI/SNF complex and cancer.

Authors:  D Reisman; S Glaros; E A Thompson
Journal:  Oncogene       Date:  2009-02-23       Impact factor: 9.867

5.  MTA1-mediated transcriptional repression of BRCA1 tumor suppressor gene.

Authors:  P R Molli; R R Singh; S W Lee; R Kumar
Journal:  Oncogene       Date:  2007-10-08       Impact factor: 9.867

Review 6.  The basics of epithelial-mesenchymal transition.

Authors:  Raghu Kalluri; Robert A Weinberg
Journal:  J Clin Invest       Date:  2009-06       Impact factor: 14.808

Review 7.  The role of the MTA family and their encoded proteins in human cancers: molecular functions and clinical implications.

Authors:  Yasushi Toh; Garth L Nicolson
Journal:  Clin Exp Metastasis       Date:  2008-12-31       Impact factor: 5.150

8.  Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice.

Authors:  G Howard; R Eiges; F Gaudet; R Jaenisch; A Eden
Journal:  Oncogene       Date:  2007-07-09       Impact factor: 9.867

9.  MBD3, a component of the NuRD complex, facilitates chromatin alteration and deposition of epigenetic marks.

Authors:  Lluis Morey; Carmen Brenner; Francesco Fazi; Raffaella Villa; Arantxa Gutierrez; Marcus Buschbeck; Clara Nervi; Saverio Minucci; Francois Fuks; Luciano Di Croce
Journal:  Mol Cell Biol       Date:  2008-07-21       Impact factor: 4.272

10.  Structural basis for the recognition of histone H4 by the histone-chaperone RbAp46.

Authors:  Natalia V Murzina; Xue-Yuan Pei; Wei Zhang; Mike Sparkes; Jose Vicente-Garcia; J Venkatesh Pratap; Stephen H McLaughlin; Tom Rolef Ben-Shahar; Alain Verreault; Ben F Luisi; Ernest D Laue
Journal:  Structure       Date:  2008-06-19       Impact factor: 5.006
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  230 in total

Review 1.  Role of MTA2 in human cancer.

Authors:  Kyle R Covington; Suzanne A W Fuqua
Journal:  Cancer Metastasis Rev       Date:  2014-12       Impact factor: 9.264

2.  Ikaros changes the face of NuRD remodeling.

Authors:  Kenneth J Oestreich; Amy S Weinmann
Journal:  Nat Immunol       Date:  2011-12-16       Impact factor: 25.606

Review 3.  Patching Broken DNA: Nucleosome Dynamics and the Repair of DNA Breaks.

Authors:  Ozge Gursoy-Yuzugullu; Nealia House; Brendan D Price
Journal:  J Mol Biol       Date:  2015-11-26       Impact factor: 5.469

4.  High Expression of miR-532-5p, a Tumor Suppressor, Leads to Better Prognosis in Ovarian Cancer Both In Vivo and In Vitro.

Authors:  Fan Wang; Jeremy T-H Chang; Chester Jingshiu Kao; R Stephanie Huang
Journal:  Mol Cancer Ther       Date:  2016-02-12       Impact factor: 6.261

5.  Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.

Authors:  Siddhartha P Kar; Jonathan Beesley; Ali Amin Al Olama; Kyriaki Michailidou; Jonathan Tyrer; ZSofia Kote-Jarai; Kate Lawrenson; Sara Lindstrom; Susan J Ramus; Deborah J Thompson; Adam S Kibel; Agnieszka Dansonka-Mieszkowska; Agnieszka Michael; Aida K Dieffenbach; Aleksandra Gentry-Maharaj; Alice S Whittemore; Alicja Wolk; Alvaro Monteiro; Ana Peixoto; Andrzej Kierzek; Angela Cox; Anja Rudolph; Anna Gonzalez-Neira; Anna H Wu; Annika Lindblom; Anthony Swerdlow; Argyrios Ziogas; Arif B Ekici; Barbara Burwinkel; Beth Y Karlan; Børge G Nordestgaard; Carl Blomqvist; Catherine Phelan; Catriona McLean; Celeste Leigh Pearce; Celine Vachon; Cezary Cybulski; Chavdar Slavov; Christa Stegmaier; Christiane Maier; Christine B Ambrosone; Claus K Høgdall; Craig C Teerlink; Daehee Kang; Daniel C Tessier; Daniel J Schaid; Daniel O Stram; Daniel W Cramer; David E Neal; Diana Eccles; Dieter Flesch-Janys; Digna R Velez Edwards; Dominika Wokozorczyk; Douglas A Levine; Drakoulis Yannoukakos; Elinor J Sawyer; Elisa V Bandera; Elizabeth M Poole; Ellen L Goode; Elza Khusnutdinova; Estrid Høgdall; Fengju Song; Fiona Bruinsma; Florian Heitz; Francesmary Modugno; Freddie C Hamdy; Fredrik Wiklund; Graham G Giles; Håkan Olsson; Hans Wildiers; Hans-Ulrich Ulmer; Hardev Pandha; Harvey A Risch; Hatef Darabi; Helga B Salvesen; Heli Nevanlinna; Henrik Gronberg; Hermann Brenner; Hiltrud Brauch; Hoda Anton-Culver; Honglin Song; Hui-Yi Lim; Iain McNeish; Ian Campbell; Ignace Vergote; Jacek Gronwald; Jan Lubiński; Janet L Stanford; Javier Benítez; Jennifer A Doherty; Jennifer B Permuth; Jenny Chang-Claude; Jenny L Donovan; Joe Dennis; Joellen M Schildkraut; Johanna Schleutker; John L Hopper; Jolanta Kupryjanczyk; Jong Y Park; Jonine Figueroa; Judith A Clements; Julia A Knight; Julian Peto; Julie M Cunningham; Julio Pow-Sang; Jyotsna Batra; Kamila Czene; Karen H Lu; Kathleen Herkommer; Kay-Tee Khaw; Keitaro Matsuo; Kenneth Muir; Kenneth Offitt; Kexin Chen; Kirsten B Moysich; Kristiina Aittomäki; Kunle Odunsi; Lambertus A Kiemeney; Leon F A G Massuger; Liesel M Fitzgerald; Linda S Cook; Lisa Cannon-Albright; Maartje J Hooning; Malcolm C Pike; Manjeet K Bolla; Manuel Luedeke; Manuel R Teixeira; Marc T Goodman; Marjanka K Schmidt; Marjorie Riggan; Markus Aly; Mary Anne Rossing; Matthias W Beckmann; Matthieu Moisse; Maureen Sanderson; Melissa C Southey; Michael Jones; Michael Lush; Michelle A T Hildebrandt; Ming-Feng Hou; Minouk J Schoemaker; Montserrat Garcia-Closas; Natalia Bogdanova; Nazneen Rahman; Nhu D Le; Nick Orr; Nicolas Wentzensen; Nora Pashayan; Paolo Peterlongo; Pascal Guénel; Paul Brennan; Paula Paulo; Penelope M Webb; Per Broberg; Peter A Fasching; Peter Devilee; Qin Wang; Qiuyin Cai; Qiyuan Li; Radka Kaneva; Ralf Butzow; Reidun Kristin Kopperud; Rita K Schmutzler; Robert A Stephenson; Robert J MacInnis; Robert N Hoover; Robert Winqvist; Roberta Ness; Roger L Milne; Ruth C Travis; Sara Benlloch; Sara H Olson; Shannon K McDonnell; Shelley S Tworoger; Sofia Maia; Sonja Berndt; Soo Chin Lee; Soo-Hwang Teo; Stephen N Thibodeau; Stig E Bojesen; Susan M Gapstur; Susanne Krüger Kjær; Tanja Pejovic; Teuvo L J Tammela; Thilo Dörk; Thomas Brüning; Tiina Wahlfors; Tim J Key; Todd L Edwards; Usha Menon; Ute Hamann; Vanio Mitev; Veli-Matti Kosma; Veronica Wendy Setiawan; Vessela Kristensen; Volker Arndt; Walther Vogel; Wei Zheng; Weiva Sieh; William J Blot; Wojciech Kluzniak; Xiao-Ou Shu; Yu-Tang Gao; Fredrick Schumacher; Matthew L Freedman; Andrew Berchuck; Alison M Dunning; Jacques Simard; Christopher A Haiman; Amanda Spurdle; Thomas A Sellers; David J Hunter; Brian E Henderson; Peter Kraft; Stephen J Chanock; Fergus J Couch; Per Hall; Simon A Gayther; Douglas F Easton; Georgia Chenevix-Trench; Rosalind Eeles; Paul D P Pharoah; Diether Lambrechts
Journal:  Cancer Discov       Date:  2016-07-17       Impact factor: 39.397

Review 6.  Epigenetic regulation of epithelial-mesenchymal transition.

Authors:  Lidong Sun; Jia Fang
Journal:  Cell Mol Life Sci       Date:  2016-07-08       Impact factor: 9.261

7.  CpG and methylation-dependent DNA binding and dynamics of the methylcytosine binding domain 2 protein at the single-molecule level.

Authors:  Hai Pan; Stephanie M Bilinovich; Parminder Kaur; Robert Riehn; Hong Wang; David C Williams
Journal:  Nucleic Acids Res       Date:  2017-09-06       Impact factor: 16.971

8.  NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination.

Authors:  Dimitri Conomos; Roger R Reddel; Hilda A Pickett
Journal:  Nat Struct Mol Biol       Date:  2014-08-24       Impact factor: 15.369

Review 9.  Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes.

Authors:  Cedric R Clapier; Janet Iwasa; Bradley R Cairns; Craig L Peterson
Journal:  Nat Rev Mol Cell Biol       Date:  2017-05-17       Impact factor: 94.444

10.  Double duty: ZMYND8 in the DNA damage response and cancer.

Authors:  Fade Gong; Kyle M Miller
Journal:  Cell Cycle       Date:  2018-03-19       Impact factor: 4.534
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