Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Detection and analysis of proteins modified by O-linked N-acetylglucosamine.

Literature DB >> 21732316

Detection and analysis of proteins modified by O-linked N-acetylglucosamine.

Natasha E Zachara¹, Keith Vosseller, Gerald W Hart.

Abstract

O-GlcNAc is a common post-translational modification of nuclear, mitochondrial, and cytoplasmic proteins that is implicated in the etiology of type II diabetes and Alzheimer's disease, as well as cardioprotection. This unit covers simple and comprehensive techniques for identifying proteins modified by O-GlcNAc, studying the enzymes that add and remove O-GlcNAc, and mapping O-GlcNAc modification sites.

Entities: Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2011 PMID： 21732316 PMCID： PMC3329785 DOI： 10.1002/0471142727.mb1706s95

Source DB: PubMed Journal: Curr Protoc Mol Biol ISSN： 1934-3647

80 in total

1. Inhibition of O-GlcNAcase in perfused rat hearts by NAG-thiazolines at the time of reperfusion is cardioprotective in an O-GlcNAc-dependent manner.

Authors: Boglarka Laczy; Susan A Marsh; Charlye A Brocks; Istvan Wittmann; John C Chatham
Journal: Am J Physiol Heart Circ Physiol Date: 2010-09-10 Impact factor: 4.733

2. Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1.

Authors: S A Caldwell; S R Jackson; K S Shahriari; T P Lynch; G Sethi; S Walker; K Vosseller; M J Reginato
Journal: Oncogene Date: 2010-03-01 Impact factor: 9.867

3. Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc.

Authors: Chin Fen Teo; Sampat Ingale; Margreet A Wolfert; Galal A Elsayed; Laszlo G Nöt; John C Chatham; Lance Wells; Geert-Jan Boons
Journal: Nat Chem Biol Date: 2010-03-21 Impact factor: 15.040

4. OGA inhibition by GlcNAc-selenazoline.

Authors: Eun Ju Kim; Dona C Love; Etzer Darout; Mohannad Abdo; Brian Rempel; Stephen G Withers; Paul R Rablen; John A Hanover; Spencer Knapp
Journal: Bioorg Med Chem Date: 2010-08-11 Impact factor: 3.641

5. Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds.

Authors: Helge C Dorfmueller; Daan M F van Aalten
Journal: FEBS Lett Date: 2009-12-16 Impact factor: 4.124

6. Quantification of O-glycosylation stoichiometry and dynamics using resolvable mass tags.

Authors: Jessica E Rexach; Claude J Rogers; Seok-Ho Yu; Jifang Tao; Yi E Sun; Linda C Hsieh-Wilson
Journal: Nat Chem Biol Date: 2010-07-25 Impact factor: 15.040

7. Enrichment and site mapping of O-linked N-acetylglucosamine by a combination of chemical/enzymatic tagging, photochemical cleavage, and electron transfer dissociation mass spectrometry.

Authors: Zihao Wang; Namrata D Udeshi; Meaghan O'Malley; Jeffrey Shabanowitz; Donald F Hunt; Gerald W Hart
Journal: Mol Cell Proteomics Date: 2009-08-19 Impact factor: 5.911

Review 8. The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine.

Authors: John A Hanover; Michael W Krause; Dona C Love
Journal: Biochim Biophys Acta Date: 2009-07-30

9. Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis.

Authors: Zihao Wang; Namrata D Udeshi; Chad Slawson; Philip D Compton; Kaoru Sakabe; Win D Cheung; Jeffrey Shabanowitz; Donald F Hunt; Gerald W Hart
Journal: Sci Signal Date: 2010-01-12 Impact factor: 8.192

10. Quantification of post-translationally modified peptides of bovine alpha-crystallin using tandem mass tags and electron transfer dissociation.

Authors: Rosa I Viner; Terry Zhang; Tonya Second; Vlad Zabrouskov
Journal: J Proteomics Date: 2009-02-24 Impact factor: 4.044

24 in total

Review 1. The roles of O-linked β-N-acetylglucosamine in cardiovascular physiology and disease.

Authors: Natasha E Zachara
Journal: Am J Physiol Heart Circ Physiol Date: 2012-01-27 Impact factor: 4.733

Review 2. Nutrient regulation of signaling and transcription.

Authors: Gerald W Hart
Journal: J Biol Chem Date: 2019-01-09 Impact factor: 5.157

3. Identifying potentially O-GlcNAcylated proteins using metabolic labeling, bioorthogonal enrichment, and Western blotting.

Authors: Narek Darabedian; Matthew R Pratt
Journal: Methods Enzymol Date: 2019-03-06 Impact factor: 1.600

4. Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis.

Authors: Jennifer A Groves; Albert Lee; Gokben Yildirir; Natasha E Zachara
Journal: Cell Stress Chaperones Date: 2013-04-26 Impact factor: 3.667

5. O-GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2.

Authors: Pei-Wen Lo; Jiun-Jie Shie; Chein-Hung Chen; Chung-Yi Wu; Tsui-Ling Hsu; Chi-Huey Wong
Journal: Proc Natl Acad Sci U S A Date: 2018-06-25 Impact factor: 11.205

6. New use for CETSA: monitoring innate immune receptor stability via post-translational modification by OGT.

Authors: Walter R Drake; Ching-Wen Hou; Natasha E Zachara; Catherine Leimkuhler Grimes
Journal: J Bioenerg Biomembr Date: 2018-04-18 Impact factor: 2.945

7. Genotypic and Phenotypic Characterization of the O-Linked Protein Glycosylation System Reveals High Glycan Diversity in Paired Meningococcal Carriage Isolates.

Authors: Bente Børud; Guro K Bårnes; Ola Brønstad Brynildsrud; Elisabeth Fritzsønn; Dominique A Caugant
Journal: J Bacteriol Date: 2018-07-25 Impact factor: 3.490