Literature DB >> 21731941

Piperazic acid-containing natural products: isolation, biological relevance and total synthesis.

Alexander J Oelke1, David J France, Tatjana Hofmann, Georg Wuitschik, Steven V Ley.   

Abstract

Since their first discovery in 1959, natural products containing the piperazic acid motif have been isolated from a variety of sources and exhibit diverse biological activity profiles. This review provides information about their isolation and biological activities, and presents an overview of recent total syntheses of these molecules.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21731941     DOI： 10.1039/c1np00041a

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  8 in total

Review 1.  Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.

Authors:  Abraham J Waldman; Tai L Ng; Peng Wang; Emily P Balskus
Journal:  Chem Rev       Date:  2017-04-04       Impact factor: 60.622

2.  A heme-dependent enzyme forms the nitrogen-nitrogen bond in piperazate.

Authors:  Yi-Ling Du; Hai-Yan He; Melanie A Higgins; Katherine S Ryan
Journal:  Nat Chem Biol       Date:  2017-06-19       Impact factor: 15.040

3.  Biosynthesis of piperazic acid via N5-hydroxy-ornithine in Kutzneria spp. 744.

Authors:  Christopher S Neumann; Wei Jiang; John R Heemstra; Erin A Gontang; Roberto Kolter; Christopher T Walsh
Journal:  Chembiochem       Date:  2012-04-20       Impact factor: 3.164

4.  Identification and characterization of the biosynthetic gene cluster of polyoxypeptin A, a potent apoptosis inducer.

Authors:  Yanhua Du; Yemin Wang; Tingting Huang; Meifeng Tao; Zixin Deng; Shuangjun Lin
Journal:  BMC Microbiol       Date:  2014-02-08       Impact factor: 3.605

5.  Solid-phase synthesis of tetrahydropyridazinedione-constrained peptides.

Authors:  Chang Won Kang; Sujeewa Ranatunga; Matthew P Sarnowski; Juan R Del Valle
Journal:  Org Lett       Date:  2014-10-08       Impact factor: 6.005

Review 6.  Flavin-dependent N-hydroxylating enzymes: distribution and application.

Authors:  Carolin Mügge; Thomas Heine; Alvaro Gomez Baraibar; Willem J H van Berkel; Caroline E Paul; Dirk Tischler
Journal:  Appl Microbiol Biotechnol       Date:  2020-06-05       Impact factor: 4.813

Review 7.  Biosynthetic modularity rules in the bisintercalator family of antitumor compounds.

Authors:  Javier Fernández; Laura Marín; Raquel Alvarez-Alonso; Saúl Redondo; Juan Carvajal; Germán Villamizar; Claudio J Villar; Felipe Lombó
Journal:  Mar Drugs       Date:  2014-05-09       Impact factor: 5.118

8.  Characterization of the aurantimycin biosynthetic gene cluster and enhancing its production by manipulating two pathway-specific activators in Streptomyces aurantiacus JA 4570.

Authors:  Houyuan Zhao; Liang Wang; Dan Wan; Jianzhao Qi; Rong Gong; Zixin Deng; Wenqing Chen
Journal:  Microb Cell Fact       Date:  2016-09-21       Impact factor: 5.328
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.