Literature DB >> 21714096

Warfarin glycosylation invokes a switch from anticoagulant to anticancer activity.

Pauline Peltier-Pain1, Shannon C Timmons, Agnès Grandemange, Etienne Benoit, Jon S Thorson.   

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Year:  2011        PMID： 21714096      PMCID： PMC3217245          DOI： 10.1002/cmdc.201100178

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  24 in total

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3.  Substrate-directed stereoselectivity in vicinal diamine-catalyzed synthesis of warfarin.

Authors:  Hyunwoo Kim; Cindy Yen; Philippa Preston; Jik Chin
Journal:  Org Lett       Date:  2006-11-09       Impact factor: 6.005

4.  Highly enantioselective michael addition of cyclic 1,3-dicarbonyl compounds to alpha,beta-unsaturated ketones.

Authors:  Jian-Wu Xie; Lei Yue; Wei Chen; Wei Du; Jin Zhu; Jin-Gen Deng; Ying-Chun Chen
Journal:  Org Lett       Date:  2007-02-01       Impact factor: 6.005

5.  Structure of warfarin in solution.

Authors:  E J Valente; E C Lingafelter; W R Porter; W F Trager
Journal:  J Med Chem       Date:  1977-11       Impact factor: 7.446

6.  Glycosyloxyamine neoglycosylation: a model study using calicheamicin.

Authors:  Randal D Goff; Shanteri Singh; Jon S Thorson
Journal:  ChemMedChem       Date:  2011-02-23       Impact factor: 3.466

7.  Organocatalytic asymmetric Michael reaction of cyclic 1,3-dicarbonyl compounds and alpha,beta-unsaturated ketones--a highly atom-economic catalytic one-step formation of optically active warfarin anticoagulant.

Authors:  Nis Halland; Tore Hansen; Karl Anker Jørgensen
Journal:  Angew Chem Int Ed Engl       Date:  2003-10-20       Impact factor: 15.336

8.  Enhancing the divergent activities of betulinic acid via neoglycosylation.

Authors:  Randal D Goff; Jon S Thorson
Journal:  Org Lett       Date:  2009-01-15       Impact factor: 6.005

Review 9.  Antitumor and antimetastatic effect of warfarin and heparins.

Authors:  Vladimir Bobek; Josef Kovarík
Journal:  Biomed Pharmacother       Date:  2004-05       Impact factor: 6.529

Review 10.  VKORC1: molecular target of coumarins.

Authors:  J Oldenburg; M Watzka; S Rost; C R Müller
Journal:  J Thromb Haemost       Date:  2007-07       Impact factor: 5.824
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  11 in total

1.  Dual targeting of the Warburg effect with a glucose-conjugated lactate dehydrogenase inhibitor.

Authors:  Emilia C Calvaresi; Carlotta Granchi; Tiziano Tuccinardi; Valeria Di Bussolo; Robert W Huigens; Hyang Yeon Lee; Rahul Palchaudhuri; Marco Macchia; Adriano Martinelli; Filippo Minutolo; Paul J Hergenrother
Journal:  Chembiochem       Date:  2013-10-31       Impact factor: 3.164

2.  Targeting Iron in Colon Cancer via Glycoconjugation of Thiosemicarbazone Prochelators.

Authors:  Eman A Akam; Elisa Tomat
Journal:  Bioconjug Chem       Date:  2016-07-29       Impact factor: 4.774

3.  Glucose conjugation for the specific targeting and treatment of cancer.

Authors:  Emilia C Calvaresi; Paul J Hergenrother
Journal:  Chem Sci       Date:  2013-06       Impact factor: 9.825

4.  Enhancement of cyclopamine via conjugation with nonmetabolic sugars.

Authors:  Randal D Goff; Jon S Thorson
Journal:  Org Lett       Date:  2012-04-27       Impact factor: 6.005

5.  Direct synthesis of β-N-glycosides by the reductive glycosylation of azides with protected and native carbohydrate donors.

Authors:  Jianbin Zheng; Kaveri Balan Urkalan; Seth B Herzon
Journal:  Angew Chem Int Ed Engl       Date:  2013-04-22       Impact factor: 15.336

6.  Natural product disaccharide engineering through tandem glycosyltransferase catalysis reversibility and neoglycosylation.

Authors:  Pauline Peltier-Pain; Karen Marchillo; Maoquan Zhou; David R Andes; Jon S Thorson
Journal:  Org Lett       Date:  2012-09-17       Impact factor: 6.005

7.  Synthesis and antibacterial activity of doxycycline neoglycosides.

Authors:  Jianjun Zhang; Larissa V Ponomareva; Karen Marchillo; Maoquan Zhou; David R Andes; Jon S Thorson
Journal:  J Nat Prod       Date:  2013-08-29       Impact factor: 4.050

8.  Neoglycosylation and neoglycorandomization: Enabling tools for the discovery of novel glycosylated bioactive probes and early stage leads.

Authors:  Randal D Goff; Jon S Thorson
Journal:  Medchemcomm       Date:  2014-08-01       Impact factor: 3.597

9.  The identification of perillyl alcohol glycosides with improved antiproliferative activity.

Authors:  Nitin S Nandurkar; Jianjun Zhang; Qing Ye; Larissa V Ponomareva; Qing-Bai She; Jon S Thorson
Journal:  J Med Chem       Date:  2014-08-25       Impact factor: 7.446

10.  Synthesis of MeON-Glycoside Derivatives of Oleanolic Acid by Neoglycosylation and Evaluation of Their Cytotoxicity Against Selected Cancer Cell Lines.

Authors:  Zhichao Du; Guolong Li; Xiaoyang Zhou; Jian Zhang
Journal:  Molecules       Date:  2021-02-02       Impact factor: 4.411
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