Literature DB >> 21704934

Initial experience with the eXtend System: a relocatable frame system for multiple-session gamma knife radiosurgery.

Faisal T Sayer1, Jonathan H Sherman, Chun-Po Yen, David J Schlesinger, Ronald Kersh, Jason P Sheehan.   

Abstract

OBJECTIVE: To present our initial experience with the Elekta eXtend System, a relocatable frame system for multiple-fraction or serial multiple-session radiosurgery.
METHODS: The eXtend System comprises a carbon-fiber frame system known as the eXtend Frame, a vacuum cushion, and a vacuum pump/vacuum surveillance system. The eXtend Frame comprises a carbon-fiber frame, a mouthpiece with dental impression, and a configurable front-piece that accepts the mouthpiece and rigidly attaches to the carbon-fiber frame. Treatment preparation involves creating a dental impression, fitting the patient to the frame system at the Gamma Knife, acquiring a stereotactic computed tomography (CT) scan, and co-registering a volumetric magnetic resonance image. Measurements taken at the time of CT imaging using high-precision electronic probes locate the patient's head within the eXtend frame. These measurements are compared to measurements taken at the time of treatment to ensure the patient is in proper treatment position. Vacuum surveillance interlocks pause the treatment if the patient moves within the eXtend frame.
RESULTS: As of June 2010, we have treated four patients at the University of Virginia with the eXtend System. In all cases treated to date, we were able to complete all fractions of the prescribed treatments. In addition, while in some cases repositioning before a given fraction required several attempts, we were able to achieve a radial repositioning error of less than 1 mm without taking new reference measurements and repeating patient setup and imaging.
CONCLUSIONS: Gamma Knife radiosurgery (GKRS) has traditionally been a single-fraction treatment modality. The eXtend System expands the range of indications for GKRS to those that may benefit from multi-fraction or serial multi-session techniques. The relocatable eXtend frame can provide non-invasive head fixation while maintaining a high accuracy, high dose, and the steep gradients associated with GKRS.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21704934     DOI: 10.1016/j.wneu.2010.12.051

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  16 in total

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4.  Emerging Indications for Fractionated Gamma Knife Radiosurgery.

Authors:  Emory McTyre; Corbin A Helis; Michael Farris; Lisa Wilkins; Darrell Sloan; William H Hinson; J Daniel Bourland; William A Dezarn; Michael T Munley; Kounosuke Watabe; Fei Xing; Adrian W Laxton; Stephen B Tatter; Michael D Chan
Journal:  Neurosurgery       Date:  2017-02-01       Impact factor: 4.654

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Authors:  John W Hopewell; William T Millar; Christer Lindquist; Håkan Nordström; Pär Lidberg; Jonas Gårding
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Authors:  Dale Ding; Chun-Po Yen; Robert M Starke; Cheng-Chia Lee; Jason P Sheehan
Journal:  J Neurooncol       Date:  2014-08-14       Impact factor: 4.130

7.  Recurrent Solitary Fibrous Tumor (Intracranial Hemangiopericytoma) Treated With a Novel Combined-Modality Radiosurgery Technique: A Case Report and Review of the Literature.

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8.  Quantifying the effects of positional uncertainties and estimating margins for Gamma-Knife® fractionated radiosurgery of large brain metastases.

Authors:  Béatrice Reiner; Peter Bownes; David L Buckley; David I Thwaites
Journal:  J Radiosurg SBRT       Date:  2017

9.  Quantifying the trigger level of the vacuum surveillance system of the Gamma-Knife eXtend™ positioning system and evaluating the potential impact on dose delivery.

Authors:  Béatrice Reiner; Peter Bownes; David L Buckley; David I Thwaites
Journal:  J Radiosurg SBRT       Date:  2016

10.  Validity of the use of nose tip motion as a surrogate for intracranial motion in mask-fixated frameless Gamma Knife® Icon™ therapy.

Authors:  Gavin Wright; Natalie Harrold; Paul Hatfield; Peter Bownes
Journal:  J Radiosurg SBRT       Date:  2017
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