Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Ramelteon and improved insomnia in alcohol-dependent patients: a case series.

Literature DB >> 21677897

Ramelteon and improved insomnia in alcohol-dependent patients: a case series.

Kirk J Brower¹, Deirdre A Conroy, Megan E Kurth, Bradley J Anderson, Michael D Stein.

Abstract

In this case series of 5 alcohol-dependent patients with insomnia who had initiated abstinence, a 4-week course of ramelteon 8 mg nightly was associated with markedly improved insomnia scores, increased total sleep time, and decreased time to fall asleep. Given its lack of abuse potential and evidence of low melatonin levels in alcoholism, ramelteon deserves further study as a treatment for insomnia in this group of patients.

Entities: Chemical Disease Species

Keywords: Pharmacotherapy; alcohol dependence; insomnia; ramelteon

Mesh：

Substances：

Year: 2011 PMID： 21677897 PMCID： PMC3113966 DOI： 10.5664/JCSM.1070

Source DB: PubMed Journal: J Clin Sleep Med ISSN： 1550-9389 Impact factor: 4.062

10 in total

1. Validation of the Insomnia Severity Index as an outcome measure for insomnia research.

Authors: C H. Bastien; A Vallières; C M. Morin
Journal: Sleep Med Date: 2001-07 Impact factor: 3.492

2. Abnormal nocturnal melatonin secretion and disordered sleep in abstinent alcoholics.

Authors: Eva Kühlwein; Richard L Hauger; Michael R Irwin
Journal: Biol Psychiatry Date: 2003-12-15 Impact factor: 13.382

3. Low-dose quetiapine is not a benign sedative-hypnotic agent.

Authors: James J Gugger; Manouchkathe Cassagnol
Journal: Am J Addict Date: 2008 Sep-Oct

4. Reliability of alcohol abusers' self-reports of drinking behavior.

Authors: L C Sobell; S A Maisto; M B Sobell; A M Cooper
Journal: Behav Res Ther Date: 1979

5. Circadian phase-shifting effects of repeated ramelteon administration in healthy adults.

Authors: Gary S Richardson; Phyllis C Zee; Sherry Wang-Weigand; Laura Rodriguez; Xuejun Peng
Journal: J Clin Sleep Med Date: 2008-10-15 Impact factor: 4.062

6. Trazodone for sleep disturbance after alcohol detoxification: a double-blind, placebo-controlled trial.

Authors: Peter D Friedmann; Jennifer S Rose; Robert Swift; Robert L Stout; Richard P Millman; Michael D Stein
Journal: Alcohol Clin Exp Res Date: 2008-07-08 Impact factor: 3.455

7. The distribution and clinical significance of sleep time misperceptions among insomniacs.

Authors: J D Edinger; A I Fins
Journal: Sleep Date: 1995-05 Impact factor: 5.849

Review 8. Efficacy and clinical safety of ramelteon: an evidence-based review.

Authors: Michael J Sateia; Paula Kirby-Long; Jennifer L Taylor
Journal: Sleep Med Rev Date: 2008-08 Impact factor: 11.609

Review 9. Insomnia, alcoholism and relapse.

Authors: Kirk J Brower
Journal: Sleep Med Rev Date: 2003-12 Impact factor: 11.609

10. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research.

Authors: D J Buysse; C F Reynolds; T H Monk; S R Berman; D J Kupfer
Journal: Psychiatry Res Date: 1989-05 Impact factor: 3.222

10 in total

8 in total

Review 8. Current and potential pharmacological treatment options for insomnia in patients with alcohol use disorder in recovery.

Authors: Timothy A Roehrs; Jessica Auciello; Jack Tseng; Garth Whiteside
Journal: Neuropsychopharmacol Rep Date: 2020-06-15

8 in total

Ramelteon and improved insomnia in alcohol-dependent patients: a case series.

1. Validation of the Insomnia Severity Index as an outcome measure for insomnia research.

2. Abnormal nocturnal melatonin secretion and disordered sleep in abstinent alcoholics.

3. Low-dose quetiapine is not a benign sedative-hypnotic agent.

4. Reliability of alcohol abusers' self-reports of drinking behavior.

5. Circadian phase-shifting effects of repeated ramelteon administration in healthy adults.

6. Trazodone for sleep disturbance after alcohol detoxification: a double-blind, placebo-controlled trial.

7. The distribution and clinical significance of sleep time misperceptions among insomniacs.

Review 8. Efficacy and clinical safety of ramelteon: an evidence-based review.

Review 9. Insomnia, alcoholism and relapse.

10. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research.

Review 1. Alcohol use disorder and sleep disturbances: a feed-forward allostatic framework.

Review 2. Alcohol Dependence and Its Relationship With Insomnia and Other Sleep Disorders.

Review 3. Sleep and substance use disorders: an update.

Review 4. Pharmacotherapy Treatment Options for Insomnia: A Primer for Clinicians.

Review 5. Melatonin in drug addiction and addiction management: Exploring an evolving multidimensional relationship.

Review 6. Role of Melatonin in the Management of Substance Addiction: A Systematic Review.

Review 7. Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review.

Review 8. Current and potential pharmacological treatment options for insomnia in patients with alcohol use disorder in recovery.