Literature DB >> 15018094

Insomnia, alcoholism and relapse.

Kirk J Brower1.   

Abstract

Insomnia and alcoholism are significantly associated in community surveys and patient samples. Insomnia occurs in 36-72% of alcoholic patients and may last for weeks to months after initiating abstinence from alcohol. Some correlates of insomnia in alcoholic patients are identical to those observed in non-alcoholic insomniacs, including anxiety and depression, tobacco smoking, and the use of alcohol to aid sleep. Other studies suggest that as the severity of alcoholism increases, so does the likelihood of insomnia in alcoholic patients. In the sleep laboratory, alcoholic patients who complain of insomnia have disrupted sleep continuity when compared to alcoholic patients without insomnia complaints. Recently sober alcoholics are also more likely than non-alcoholics to have sleep-disordered breathing and increased periodic leg movements, which might contribute to insomnia in some alcoholic patients. The co-occurrence of insomnia and alcoholism is clinically significant because alcoholism can exacerbate the adverse consequences of insomnia (e.g. mood changes and performance decrements) and because insomnia among patients entering treatment for alcoholism has been significantly associated with subsequent alcoholic relapse. Baseline polysomnographic correlates of subsequent relapse include prolonged sleep latency, decreased sleep efficiency and total sleep time, increased rapid eye movement sleep pressure, and decreased slow wave sleep. Whether treatment of insomnia in alcoholic patients reduces relapse rates is unknown, but preliminary treatment guidelines that accommodate the special characteristics of alcoholic patients are provided, with a goal to reduce daytime impairment and psychological distress.

Entities:  

Mesh:

Substances:

Year:  2003        PMID: 15018094     DOI: 10.1016/s1087-0792(03)90005-0

Source DB:  PubMed          Journal:  Sleep Med Rev        ISSN: 1087-0792            Impact factor:   11.609


  127 in total

1.  Open pilot study of gabapentin versus trazodone to treat insomnia in alcoholic outpatients.

Authors:  Maher Karam-Hage; Kirk J Brower
Journal:  Psychiatry Clin Neurosci       Date:  2003-10       Impact factor: 5.188

2.  Prevalence and correlates of insomnia in a polish sample of alcohol-dependent patients.

Authors:  Nataliya Zhabenko; Marcin Wojnar; Kirk J Brower
Journal:  Alcohol Clin Exp Res       Date:  2012-04-04       Impact factor: 3.455

3.  Role of wake-promoting basal forebrain and adenosinergic mechanisms in sleep-promoting effects of ethanol.

Authors:  Mahesh M Thakkar; Samuel C Engemann; Rishi Sharma; Pradeep Sahota
Journal:  Alcohol Clin Exp Res       Date:  2010-04-05       Impact factor: 3.455

4.  Persistent insomnia, abstinence, and moderate drinking in alcohol-dependent individuals.

Authors:  Kirk J Brower; Amy Krentzman; Elizabeth A R Robinson
Journal:  Am J Addict       Date:  2011-07-18

Review 5.  Mechanisms underlying sleep-wake disturbances in alcoholism: focus on the cholinergic pedunculopontine tegmentum.

Authors:  Clifford M Knapp; Domenic A Ciraulo; Subimal Datta
Journal:  Behav Brain Res       Date:  2014-08-20       Impact factor: 3.332

6.  Perception of sleep in recovering alcohol-dependent patients with insomnia: relationship with future drinking.

Authors:  Deirdre A Conroy; J Todd Arnedt; Kirk J Brower; Stephen Strobbe; Flavia Consens; Robert Hoffmann; Roseanne Armitage
Journal:  Alcohol Clin Exp Res       Date:  2006-12       Impact factor: 3.455

7.  Sleep quality and alcohol risk in college students: examining the moderating effects of drinking motives.

Authors:  Shannon R Kenney; Andrew P Paves; Elizabeth M Grimaldi; Joseph W LaBrie
Journal:  J Am Coll Health       Date:  2014

8.  The CC genotype in the T102C HTR2A polymorphism predicts relapse in individuals after alcohol treatment.

Authors:  Andrzej Jakubczyk; Anna Klimkiewicz; Maciej Kopera; Aleksandra Krasowska; Małgorzata Wrzosek; Halina Matsumoto; Margit Burmeister; Kirk J Brower; Marcin Wojnar
Journal:  J Psychiatr Res       Date:  2013-01-12       Impact factor: 4.791

Review 9.  Psychiatric disorders and sleep.

Authors:  Andrew D Krystal
Journal:  Neurol Clin       Date:  2012-11       Impact factor: 3.806

10.  Normalizing effects of modafinil on sleep in chronic cocaine users.

Authors:  Peter T Morgan; Edward Pace-Schott; Brian Pittman; Robert Stickgold; Robert T Malison
Journal:  Am J Psychiatry       Date:  2010-01-15       Impact factor: 18.112

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.