| Literature DB >> 21674107 |
John B Matson1, Samuel I Stupp.
Abstract
Hydrolytically-labile hydrazones in peptide amphiphiles were studied as degradable tethers for release of the drug nabumetone from nanofiber gels. On-resin addition of the novel compound tri-Boc-hydrazido adipic acid to a lysine ε-amine allowed for precise placement of a hydrazide in a peptide sequence.Entities:
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Year: 2011 PMID: 21674107 PMCID: PMC3292209 DOI: 10.1039/c1cc12570b
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222