| Literature DB >> 25251829 |
Martin Conda-Sheridan1, Sungsoo S Lee, Adam T Preslar, Samuel I Stupp.
Abstract
Nanofibre forming peptide amphiphiles were conjugated to naproxen through an esterase-sensitive linker. The amount of naproxen released, in the presence of enzymes, was influenced by the linker conjugating the drug to the supramolecular assembly. In vitro studies showed the anti-inflammatory activity of the released drug was maintained.Entities:
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Year: 2014 PMID: 25251829 PMCID: PMC4201510 DOI: 10.1039/c4cc06340f
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222