Literature DB >> 21672905

2010 translational bioinformatics year in review.

Russ B Altman1, Katharine S Miller.   

Abstract

A review of 2010 research in translational bioinformatics provides much to marvel at. We have seen notable advances in personal genomics, pharmacogenetics, and sequencing. At the same time, the infrastructure for the field has burgeoned. While acknowledging that, according to researchers, the members of this field tend to be overly optimistic, the authors predict a bright future.

Mesh:

Year:  2011        PMID: 21672905      PMCID: PMC3128418          DOI: 10.1136/amiajnl-2011-000328

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  25 in total

Review 1.  Toward a complete in silico, multi-layered embryonic stem cell regulatory network.

Authors:  Huilei Xu; Christoph Schaniel; Ihor R Lemischka; Avi Ma'ayan
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2010 Nov-Dec

2.  Over-optimism in bioinformatics research.

Authors:  Anne-Laure Boulesteix
Journal:  Bioinformatics       Date:  2009-11-26       Impact factor: 6.937

3.  Principles of human subjects protections applied in an opt-out, de-identified biobank.

Authors:  Jill Pulley; Ellen Clayton; Gordon R Bernard; Dan M Roden; Daniel R Masys
Journal:  Clin Transl Sci       Date:  2010-02       Impact factor: 4.689

4.  In silico research in the era of cloud computing.

Authors:  Joel T Dudley; Atul J Butte
Journal:  Nat Biotechnol       Date:  2010-11       Impact factor: 54.908

5.  Web-based, participant-driven studies yield novel genetic associations for common traits.

Authors:  Nicholas Eriksson; J Michael Macpherson; Joyce Y Tung; Lawrence S Hon; Brian Naughton; Serge Saxonov; Linda Avey; Anne Wojcicki; Itsik Pe'er; Joanna Mountain
Journal:  PLoS Genet       Date:  2010-06-24       Impact factor: 5.917

6.  PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations.

Authors:  Joshua C Denny; Marylyn D Ritchie; Melissa A Basford; Jill M Pulley; Lisa Bastarache; Kristin Brown-Gentry; Deede Wang; Dan R Masys; Dan M Roden; Dana C Crawford
Journal:  Bioinformatics       Date:  2010-03-24       Impact factor: 6.937

7.  An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus.

Authors:  Chirag J Patel; Jayanta Bhattacharya; Atul J Butte
Journal:  PLoS One       Date:  2010-05-20       Impact factor: 3.240

8.  Mining multi-item drug adverse effect associations in spontaneous reporting systems.

Authors:  Rave Harpaz; Herbert S Chase; Carol Friedman
Journal:  BMC Bioinformatics       Date:  2010-10-28       Impact factor: 3.169

9.  Drug off-target effects predicted using structural analysis in the context of a metabolic network model.

Authors:  Roger L Chang; Li Xie; Lei Xie; Philip E Bourne; Bernhard Ø Palsson
Journal:  PLoS Comput Biol       Date:  2010-09-23       Impact factor: 4.475

10.  A side effect resource to capture phenotypic effects of drugs.

Authors:  Michael Kuhn; Monica Campillos; Ivica Letunic; Lars Juhl Jensen; Peer Bork
Journal:  Mol Syst Biol       Date:  2010-01-19       Impact factor: 11.429

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  6 in total

Review 1.  Surveying Recent Themes in Translational Bioinformatics: Big Data in EHRs, Omics for Drugs, and Personal Genomics.

Authors:  J C Denny
Journal:  Yearb Med Inform       Date:  2014-08-15

Review 2.  Translational bioinformatics embraces big data.

Authors:  N H Shah
Journal:  Yearb Med Inform       Date:  2012

3.  Calibrating predictive model estimates to support personalized medicine.

Authors:  Xiaoqian Jiang; Melanie Osl; Jihoon Kim; Lucila Ohno-Machado
Journal:  J Am Med Inform Assoc       Date:  2011-10-07       Impact factor: 4.497

4.  I-spline Smoothing for Calibrating Predictive Models.

Authors:  Yuan Wu; Xiaoqian Jiang; Jihoon Kim; Lucila Ohno-Machado
Journal:  AMIA Jt Summits Transl Sci Proc       Date:  2012-03-19

Review 5.  Trends in IT Innovation to Build a Next Generation Bioinformatics Solution to Manage and Analyse Biological Big Data Produced by NGS Technologies.

Authors:  Alexandre G de Brevern; Jean-Philippe Meyniel; Cécile Fairhead; Cécile Neuvéglise; Alain Malpertuy
Journal:  Biomed Res Int       Date:  2015-06-01       Impact factor: 3.411

6.  Recent trends in biomedical informatics: a study based on JAMIA articles.

Authors:  Xiaoqian Jiang; Krystal Tse; Shuang Wang; Son Doan; Hyeoneui Kim; Lucila Ohno-Machado
Journal:  J Am Med Inform Assoc       Date:  2013-11-08       Impact factor: 4.497

  6 in total

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