Literature DB >> 21658334

Deep wound infection following pediatric scoliosis surgery: incidence and analysis of risk factors.

Sami Aleissa1, David Parsons, John Grant, James Harder, Jason Howard.   

Abstract

BACKGROUND: Deep wound infection after spinal surgery is a severe complication that often requires prolonged medical and surgical management. It can compromise the outcome of the deformity correction, especially in patients requiring surgical intervention with subsequent removal of implants. Ascertaining the incidence and risk factors leading to infection may help to prevent this problem.
METHODS: We reviewed the hospital charts of all patients who underwent spinal deformity correction from 1996 to 2005.
RESULTS: In all, 227 patients were identified (139 idiopathic, 57 neuromuscular, 8 syndromic, 6 congenital, 17 other); 191 patients were treated with posterior instrumentation and fusion, 11 with anterior-only procedures and 24 with combined anterior and posterior procedures. Final follow-up ranged from 1 to 9.5 years. Infection developed in 14 patients. The overall incidence of infection was 6.2%. Drainage and back pain were the most common presenting symptoms. The incidence of infection was higher among patients with nonidiopathic diagnoses (risk ratio [RR] 8.65, p < 0.001). Use of allograft bone was associated with a higher rate of infection (RR 9.66, p < 0.001) even when stratified by diagnosis (nonidiopathic diagnoses, RR 7.6, p = 0.012). Higher volume of instrumentation was also a risk factor for infection (p = 0.022). Coagulase-negative Staphyloccocus was the most commonly identified organism, followed by Propionibacterium acnes and Pseudomonas.
CONCLUSION: Development of infection following scoliosis surgery was found to be associated with several risk factors, including a nonidiopathic diagnosis, the use of allograft and a higher volume of instrumentation. Preventative measures addressing these factors may decrease the rate of infection.

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Year:  2011        PMID: 21658334      PMCID: PMC3191901          DOI: 10.1503/cjs.008210

Source DB:  PubMed          Journal:  Can J Surg        ISSN: 0008-428X            Impact factor:   2.089


  34 in total

1.  Late-developing infection in instrumented idiopathic scoliosis.

Authors:  C E Clark; H L Shufflebarger
Journal:  Spine (Phila Pa 1976)       Date:  1999-09-15       Impact factor: 3.468

2.  Allograft bone in spinal fusion for adolescent idiopathic scoliosis.

Authors:  D Raymond Knapp; Eric T Jones; John S Blanco; Joseph C Flynn; Charles T Price
Journal:  J Spinal Disord Tech       Date:  2005-02

3.  Spinal fusion augmented by luque-rod segmental instrumentation for neuromuscular scoliosis.

Authors:  M J Broom; J V Banta; T S Renshaw
Journal:  J Bone Joint Surg Am       Date:  1989-01       Impact factor: 5.284

4.  Efficacy of dilute betadine solution irrigation in the prevention of postoperative infection of spinal surgery.

Authors:  Ming-Te Cheng; Ming-Chau Chang; Shih-Tien Wang; Wing-Kwang Yu; Chien-Lin Liu; Tain-Hsiung Chen
Journal:  Spine (Phila Pa 1976)       Date:  2005-08-01       Impact factor: 3.468

5.  The relationship between preoperative nutritional status and complications after an operation for scoliosis in patients who have cerebral palsy.

Authors:  D S Jevsevar; L I Karlin
Journal:  J Bone Joint Surg Am       Date:  1993-06       Impact factor: 5.284

6.  Freeze-dried allograft for posterior spinal fusion in patients with neuromuscular spinal deformities.

Authors:  M Yazici; M A Asher
Journal:  Spine (Phila Pa 1976)       Date:  1997-07-01       Impact factor: 3.468

7.  Delayed infection after elective spinal instrumentation and fusion. A retrospective analysis of eight cases.

Authors:  R W Viola; H A King; S M Adler; C B Wilson
Journal:  Spine (Phila Pa 1976)       Date:  1997-10-15       Impact factor: 3.468

8.  Adherence and biofilm formation of Staphylococcus epidermidis and Mycobacterium tuberculosis on various spinal implants.

Authors:  Kee-Yong Ha; Yang-Guk Chung; Seung-Joon Ryoo
Journal:  Spine (Phila Pa 1976)       Date:  2005-01-01       Impact factor: 3.468

9.  Wound infection after spinal fusion in children with cerebral palsy.

Authors:  G Szöke; G Lipton; F Miller; K Dabney
Journal:  J Pediatr Orthop       Date:  1998 Nov-Dec       Impact factor: 2.324

Review 10.  Prophylactic parenteral antibiotics in clean neurosurgical procedures: a review.

Authors:  R Dempsey; R P Rapp; B Young; S Johnston; P Tibbs
Journal:  J Neurosurg       Date:  1988-07       Impact factor: 5.115

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  18 in total

1.  Surgical site infection after pediatric spinal deformity surgery.

Authors:  Ying Li; Michael Glotzbecker; Daniel Hedequist
Journal:  Curr Rev Musculoskelet Med       Date:  2012-02-09

2.  Origin of propionibacterium in surgical wounds and evidence-based approach for culturing propionibacterium from surgical sites.

Authors:  Frederick A Matsen; Susan Butler-Wu; Bradley C Carofino; Jocelyn L Jette; Alexander Bertelsen; Roger Bumgarner
Journal:  J Bone Joint Surg Am       Date:  2013-12-04       Impact factor: 5.284

Review 3.  Risk factors for surgical site infection following pediatric spinal deformity surgery: a systematic review and meta-analysis.

Authors:  Fei Meng; Junming Cao; Xianzhong Meng
Journal:  Childs Nerv Syst       Date:  2015-02-24       Impact factor: 1.475

Review 4.  Complications following spine fusion for adolescent idiopathic scoliosis.

Authors:  Robert F Murphy; James F Mooney
Journal:  Curr Rev Musculoskelet Med       Date:  2016-12

5.  Is Propionibacterium acnes becoming the most common bacteria in delayed infections following adolescent idiopathic scoliosis surgery?

Authors:  Mayur P Kardile; Sukhraj S Bains; Calvin C Kuo; Todd L Lincoln; Ravi S Bains
Journal:  Spine Deform       Date:  2021-02-08

6.  Intercellular adhesion molecule-1 (ICAM-1, CD54) is increased in adhesive capsulitis.

Authors:  Yang-Soo Kim; Jung-Man Kim; Yun-Gyoung Lee; Oak-Kee Hong; Hyuk-Sang Kwon; Jong-Hoon Ji
Journal:  J Bone Joint Surg Am       Date:  2013-02-20       Impact factor: 5.284

7.  Skeletal muscle and plasma concentrations of cefazolin during complex paediatric spinal surgery.

Authors:  A S Himebauch; W N Sankar; J M Flynn; M T Sisko; G S Moorthy; J S Gerber; A F Zuppa; E Fox; J P Dormans; T J Kilbaugh
Journal:  Br J Anaesth       Date:  2016-07       Impact factor: 9.166

Review 8.  Should we start treating chronic low back pain with antibiotics rather than with pain medications?

Authors:  Christof Birkenmaier
Journal:  Korean J Pain       Date:  2013-10-02

9.  A systematic scoping review of adherence to reporting guidelines in health care literature.

Authors:  Zainab Samaan; Lawrence Mbuagbaw; Daisy Kosa; Victoria Borg Debono; Rejane Dillenburg; Shiyuan Zhang; Vincent Fruci; Brittany Dennis; Monica Bawor; Lehana Thabane
Journal:  J Multidiscip Healthc       Date:  2013-05-06

10.  Infection related never events in pediatric patients undergoing spinal fusion procedures in United States: prevalence and predictors.

Authors:  Veerajalandhar Allareddy; Veerasathpurush Allareddy; Romesh P Nalliah; Sankeerth Rampa; Min Kyeong Lee
Journal:  PLoS One       Date:  2013-11-05       Impact factor: 3.240

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