Literature DB >> 2164640

The cytomegalovirus enhancer: a pan-active control element in transgenic mice.

E V Schmidt1, G Christoph, R Zeller, P Leder.   

Abstract

In an effort to identify widely active positive regulatory elements, we have examined the action of the cytomegalovirus enhancer-promoter in transgenic mice. These elements activated expression in 24 of 28 tissues tested. The greatest expression was observed in the heart, kidney, brain, and testis. Maximum expression further localized to specific cells within the heart and kidney.

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Year:  1990        PMID: 2164640      PMCID: PMC361001          DOI: 10.1128/mcb.10.8.4406-4411.1990

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN: 0270-7306            Impact factor:   4.272


  17 in total

1.  Activation of the major immediate early gene of human cytomegalovirus by cis-acting elements in the promoter-regulatory sequence and by virus-specific trans-acting components.

Authors:  M F Stinski; T J Roehr
Journal:  J Virol       Date:  1985-08       Impact factor: 5.103

Review 2.  The cytomegaloviruses: ubiquitous agents with protean clinical manifestations. II.

Authors:  T H Weller
Journal:  N Engl J Med       Date:  1971-07-29       Impact factor: 91.245

3.  Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter.

Authors:  D A Melton; P A Krieg; M R Rebagliati; T Maniatis; K Zinn; M R Green
Journal:  Nucleic Acids Res       Date:  1984-09-25       Impact factor: 16.971

4.  Promoter-regulatory region of the major immediate early gene of human cytomegalovirus.

Authors:  D R Thomsen; R M Stenberg; W F Goins; M F Stinski
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

5.  A vector that replicates as a plasmid and can be efficiently selected in B-lymphoblasts transformed by Epstein-Barr virus.

Authors:  B Sugden; K Marsh; J Yates
Journal:  Mol Cell Biol       Date:  1985-02       Impact factor: 4.272

6.  A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus.

Authors:  M Boshart; F Weber; G Jahn; K Dorsch-Häsler; B Fleckenstein; W Schaffner
Journal:  Cell       Date:  1985-06       Impact factor: 41.582

7.  The human beta-globin gene and a functional viral thymidine kinase gene in developing mice.

Authors:  E F Wagner; T A Stewart; B Mintz
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

8.  Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene.

Authors:  W J Muller; E Sinn; P K Pattengale; R Wallace; P Leder
Journal:  Cell       Date:  1988-07-01       Impact factor: 41.582

9.  Multiple spliced and unspliced transcripts from human cytomegalovirus immediate-early region 2 and evidence for a common initiation site within immediate-early region 1.

Authors:  R M Stenberg; P R Witte; M F Stinski
Journal:  J Virol       Date:  1985-12       Impact factor: 5.103

Review 10.  Latent infection and the elusive cytomegalovirus.

Authors:  M C Jordan
Journal:  Rev Infect Dis       Date:  1983 Mar-Apr
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  72 in total

1.  E4ORF3 requirement for achieving long-term transgene expression from the cytomegalovirus promoter in adenovirus vectors.

Authors:  D Armentano; M P Smith; C C Sookdeo; J Zabner; M A Perricone; J A St George; S C Wadsworth; R J Gregory
Journal:  J Virol       Date:  1999-08       Impact factor: 5.103

2.  Genomic targeting with a positive-selection lox integration vector allows highly reproducible gene expression in mammalian cells.

Authors:  S Fukushige; B Sauer
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-01       Impact factor: 11.205

3.  Activation of the CMV-IE promoter by hyperthermia in vitro and in vivo: biphasic heat induction of cytosine deaminase suicide gene expression.

Authors:  Dennis Kobelt; Jutta Aumann; Iduna Fichtner; Ulrike Stein; Peter M Schlag; Wolfgang Walther
Journal:  Mol Biotechnol       Date:  2010-10       Impact factor: 2.695

4.  Optimized expression vector for ion channel studies in Xenopus oocytes and mammalian cells using alfalfa mosaic virus.

Authors:  Srinivasan P Venkatachalan; Jeremy D Bushman; José L Mercado; Feyza Sancar; Kelly R Christopherson; Andrew J Boileau
Journal:  Pflugers Arch       Date:  2006-12-05       Impact factor: 3.657

5.  In vivo direct molecular imaging of early tumorigenesis and malignant progression induced by transgenic expression of GFP-Met.

Authors:  Sharon Moshitch-Moshkovitz; Galia Tsarfaty; Dafna W Kaufman; Gideon Y Stein; Keren Shichrur; Eddy Solomon; Robert H Sigler; James H Resau; George F Vande Woude; Ilan Tsarfaty
Journal:  Neoplasia       Date:  2006-05       Impact factor: 5.715

6.  Therapeutic effect of a Gag-nuclease fusion protein against retroviral infection in vivo.

Authors:  G Schumann; M Hermankova; K Cannon; J L Mankowski; J D Boeke
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

7.  CMV enhancer-promoter is preferentially active in exocrine cells in vivo.

Authors:  D B Vasey; S G Lillico; H M Sang; T J King; C B A Whitelaw
Journal:  Transgenic Res       Date:  2008-12-16       Impact factor: 2.788

8.  Cytomegalovirus promoter up-regulation is the major cause of increased protein levels of unstable reporter proteins after treatment of living cells with proteasome inhibitors.

Authors:  Beatriz Alvarez-Castelao; Idoia Martín-Guerrero; Africa García-Orad; José G Castaño
Journal:  J Biol Chem       Date:  2009-08-13       Impact factor: 5.157

9.  Analysis of the promoter and cis-acting elements regulating expression of herpes simplex virus type 2 latency-associated transcripts.

Authors:  K Wang; P R Krause; S E Straus
Journal:  J Virol       Date:  1995-05       Impact factor: 5.103

10.  Analysis of human CD59 tissue expression directed by the CMV-IE-1 promoter in transgenic rats.

Authors:  B Charreau; L Tesson; J Buscail; J P Soulillou; I Anegon
Journal:  Transgenic Res       Date:  1996-11       Impact factor: 2.788

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