Literature DB >> 21643791

The role of memory-related gene polymorphisms, KIBRA and CLSTN2, on replicate memory assessment in the elderly.

N Sédille-Mostafaie1, C Sebesta, K R Huber, S Zehetmayer, S Jungwirth, K H Tragl, P Fischer, W Krugluger.   

Abstract

The role of the CLSTN2 (rs6439886) and KIBRA (rs17070145) SNPs in cognitive impairment was analysed in a 75-76 years old group. Various memory assessment tests were carried out on individuals at baseline and during follow-up investigations, and biallelic genotyping was performed. No influence of the allele status of either SNPs was observed on any memory test. No increased risk of any type of late development, and cognitive impairment was associated with rs6439886 or rs17070145.

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Year:  2011        PMID： 21643791     DOI： 10.1007/s00702-011-0667-9

Source DB:  PubMed          Journal:  J Neural Transm (Vienna)        ISSN： 0300-9564            Impact factor:   3.575


  17 in total

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7.  Serum KIBRA mRNA and Protein Expression and Cognitive Functions in Depression.

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