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Literature DB >> 24642126

KIBRA: In the brain and beyond.

Lin Zhang¹, Shuping Yang¹, Dirk Oliver Wennmann², Yuanhong Chen¹, Joachim Kremerskothen², Jixin Dong³.

Abstract

In mammals, the KIBRA locus has been associated with memory performance and cognition by genome-wide single nucleotide polymorphism screening. Genetic studies in Drosophila and human cells have identified KIBRA as a novel regulator of the Hippo signaling pathway, which plays a critical role in human tumorigenesis. Recent studies also indicated that KIBRA is involved in other physiological processes including cell polarity, membrane/vesicular trafficking, mitosis and cell migration. At the biochemical level, KIBRA protein is highly phosphorylated by various kinases in epithelial cells. Here, we discuss the updates concerning the function and regulation of KIBRA in the brain and beyond.

Entities: CellLine Chemical Disease Gene Mutation Species

Keywords: Cell migration; Cell polarity; Hippo pathway; KIBRA; Memory performance; Phosphorylation

Mesh：

Substances：

Year: 2014 PMID： 24642126 PMCID： PMC4032603 DOI： 10.1016/j.cellsig.2014.02.023

Source DB: PubMed Journal: Cell Signal ISSN： 0898-6568 Impact factor: 4.315

84 in total

1. Association study of KIBRA gene with memory performance in a Japanese population.

Authors: Yuka Yasuda; Ryota Hashimoto; Kazutaka Ohi; Motoyuki Fukumoto; Hironori Takamura; Naomi Iike; Tetsuhiko Yoshida; Noriyuki Hayashi; Hidetoshi Takahashi; Hidenaga Yamamori; Takashi Morihara; Shinji Tagami; Masayasu Okochi; Toshihisa Tanaka; Takashi Kudo; Kouzin Kamino; Ryohei Ishii; Masao Iwase; Hiroaki Kazui; Masatoshi Takeda
Journal: World J Biol Psychiatry Date: 2010-10 Impact factor: 4.132

2. Clcn4-2 genomic structure differs between the X locus in Mus spretus and the autosomal locus in Mus musculus: AT motif enrichment on the X.

Authors: Di Kim Nguyen; Fan Yang; Rajinder Kaul; Can Alkan; Anthony Antonellis; Karen F Friery; Baoli Zhu; Pieter J de Jong; Christine M Disteche
Journal: Genome Res Date: 2011-01-31 Impact factor: 9.043

3. KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals.

Authors: S Moleirinho; N Chang; A H Sims; A M Tilston-Lünel; L Angus; A Steele; V Boswell; S C Barnett; C Ormandy; D Faratian; F J Gunn-Moore; P A Reynolds
Journal: Oncogene Date: 2012-05-21 Impact factor: 9.867

4. KIBRA modulates directional migration of podocytes.

Authors: Kerstin Duning; Eva-Maria Schurek; Marc Schlüter; Michael Bayer; Hans-Christian Reinhardt; Albrecht Schwab; Liliana Schaefer; Thomas Benzing; Bernhard Schermer; Moin A Saleem; Tobias B Huber; Sebastian Bachmann; Joachim Kremerskothen; Thomas Weide; Hermann Pavenstädt
Journal: J Am Soc Nephrol Date: 2008-07-02 Impact factor: 10.121

5. KIBRA: A New Gateway to Learning and Memory?

Authors: Armin Schneider; Matthew J Huentelman; Joachim Kremerskothen; Kerstin Duning; Robert Spoelgen; Karoly Nikolich
Journal: Front Aging Neurosci Date: 2010-02-12 Impact factor: 5.750

6. Phosphorylation of KIBRA by the extracellular signal-regulated kinase (ERK)-ribosomal S6 kinase (RSK) cascade modulates cell proliferation and migration.

Authors: Shuping Yang; Ming Ji; Lin Zhang; Yuanhong Chen; Dirk Oliver Wennmann; Joachim Kremerskothen; Jixin Dong
Journal: Cell Signal Date: 2013-11-19 Impact factor: 4.315

7. Both PKMζ and KIBRA are closely related to reference memory but not working memory in a T-maze task in rats.

Authors: Dean-Chuan Wang; Pei-Chun Liu; Hui-Shan Hung; Tsan-Ju Chen
Journal: J Comp Physiol A Neuroethol Sens Neural Behav Physiol Date: 2013-10-20 Impact factor: 1.836

8. Human Mob1 proteins are required for cytokinesis by controlling microtubule stability.

Authors: Claudia Florindo; Joana Perdigão; Didier Fesquet; Elmar Schiebel; Jonathon Pines; Alvaro A Tavares
Journal: J Cell Sci Date: 2012-03-27 Impact factor: 5.285

9. The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals.

Authors: Nailing Zhang; Haibo Bai; Karen K David; Jixin Dong; Yonggang Zheng; Jing Cai; Marco Giovannini; Pentao Liu; Robert A Anders; Duojia Pan
Journal: Dev Cell Date: 2010-07-20 Impact factor: 12.270

10. KIBRA genetic polymorphism influences episodic memory in later life, but does not increase the risk of mild cognitive impairment.

Authors: O P Almeida; S G Schwab; N T Lautenschlager; B Morar; K R Greenop; L Flicker; D Wildenauer
Journal: J Cell Mol Med Date: 2008-01-11 Impact factor: 5.310

25 in total

1. ACTL6A Is Co-Amplified with p63 in Squamous Cell Carcinoma to Drive YAP Activation, Regenerative Proliferation, and Poor Prognosis.

Authors: Srinivas Vinod Saladi; Kenneth Ross; Mihriban Karaayvaz; Purushothama R Tata; Hongmei Mou; Jayaraj Rajagopal; Sridhar Ramaswamy; Leif W Ellisen
Journal: Cancer Cell Date: 2016-12-29 Impact factor: 31.743

2. De Novo Coding Variants Are Strongly Associated with Tourette Disorder.

Authors: A Jeremy Willsey; Thomas V Fernandez; Dongmei Yu; Robert A King; Andrea Dietrich; Jinchuan Xing; Stephan J Sanders; Jeffrey D Mandell; Alden Y Huang; Petra Richer; Louw Smith; Shan Dong; Kaitlin E Samocha; Benjamin M Neale; Giovanni Coppola; Carol A Mathews; Jay A Tischfield; Jeremiah M Scharf; Matthew W State; Gary A Heiman
Journal: Neuron Date: 2017-05-03 Impact factor: 17.173

3. Isoform Specificity of PKMs during Long-Term Facilitation in Aplysia Is Mediated through Stabilization by KIBRA.

Authors: Larissa Ferguson; Jiangyuan Hu; Diancai Cai; Shanping Chen; Tyler W Dunn; Kaycey Pearce; David L Glanzman; Samuel Schacher; Wayne S Sossin
Journal: J Neurosci Date: 2019-09-19 Impact factor: 6.167

4. Phosphorylation-Dependent Regulation of the DNA Damage Response of Adaptor Protein KIBRA in Cancer Cells.

Authors: Jayadev Mavuluri; Swarnalatha Beesetti; Rohan Surabhi; Joachim Kremerskothen; Ganesh Venkatraman; Suresh K Rayala
Journal: Mol Cell Biol Date: 2016-04-15 Impact factor: 4.272

5. Generation and Profiling of Tumor-Homing Induced Neural Stem Cells from the Skin of Cancer Patients.

Authors: Andrew Buckley; Shaye B Hagler; Vivien Lettry; Juli R Bagó; Spencer M Maingi; Simon Khagi; Matthew G Ewend; C Ryan Miller; Shawn D Hingtgen
Journal: Mol Ther Date: 2020-04-29 Impact factor: 11.454

6. Selective Erasure of Distinct Forms of Long-Term Synaptic Plasticity Underlying Different Forms of Memory in the Same Postsynaptic Neuron.

Authors: Jiangyuan Hu; Larissa Ferguson; Kerry Adler; Carole A Farah; Margaret H Hastings; Wayne S Sossin; Samuel Schacher
Journal: Curr Biol Date: 2017-06-22 Impact factor: 10.834

7. KIBRA promotes prostate cancer cell proliferation and motility.

Authors: Seth Stauffer; Xingcheng Chen; Lin Zhang; Yuanhong Chen; Jixin Dong
Journal: FEBS J Date: 2016-04-05 Impact factor: 5.542

8. Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.

Authors: Tara E Tracy; Peter Dongmin Sohn; S Sakura Minami; Chao Wang; Sang-Won Min; Yaqiao Li; Yungui Zhou; David Le; Iris Lo; Ravikumar Ponnusamy; Xin Cong; Birgit Schilling; Lisa M Ellerby; Richard L Huganir; Li Gan
Journal: Neuron Date: 2016-03-31 Impact factor: 17.173

9. Dexmedetomidine attenuates cisplatin-induced cognitive impairment by modulating miR-429-3p expression in rats.

Authors: Chang Li; Jiangfeng Niu; Bin Zhou; Wei Deng; Fumou Deng; Zhidong Zhou; Guohai Xu
Journal: 3 Biotech Date: 2020-05-10 Impact factor: 2.406

10. Distinctive phosphoinositide- and Ca²⁺-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain.

Authors: Mareike G Posner; Abhishek Upadhyay; Rieko Ishima; Antreas C Kalli; Gemma Harris; Joachim Kremerskothen; Mark S P Sansom; Susan J Crennell; Stefan Bagby
Journal: J Biol Chem Date: 2018-05-03 Impact factor: 5.157