Literature DB >> 21636592

The FAF-Drugs2 server: a multistep engine to prepare electronic chemical compound collections.

David Lagorce1, Julien Maupetit, Jonathan Baell, Olivier Sperandio, Pierre Tufféry, Maria A Miteva, Hervé Galons, Bruno O Villoutreix.   

Abstract

SUMMARY: The FAF-Drugs2 server is a web application that prepares chemical compound libraries prior to virtual screening or that assists hit selection/lead optimization before chemical synthesis or ordering. The FAF-Drugs2 web server is an enhanced version of the FAF-Drugs2 package that now includes Pan Assay Interference Compounds detection. This online toolkit has been designed through a user-centered approach with emphasis on user-friendliness. This is a unique online tool allowing to prepare large compound libraries with in house or user-defined filtering parameters. AVAILABILITY: The FAF-Drugs2 server is freely available at http://bioserv.rpbs.univ-paris-diderot.fr/FAF-Drugs/.

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Year:  2011        PMID： 21636592     DOI： 10.1093/bioinformatics/btr333

Source DB:  PubMed          Journal:  Bioinformatics        ISSN： 1367-4803            Impact factor:   6.937


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