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Literature DB >> 2162164

A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein.

Abstract

The XJC13 strain of Junin virus (JV) and the mouse-attenuated mutant C167 showed different GP38 peptide mapping after limited proteolysis with ficin and papain; viral infectivity of both viruses also exhibited a different susceptibility to protease treatment. A correlation between envelope glycoprotein alteration and JV virulence in neonatal mice is proposed.

Entities: Gene Species

Mesh：

Substances：

Year: 1990 PMID： 2162164 DOI： 10.1007/BF01311059

Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574

13 in total

1. [Attenuation in the virulence of a mutant of Junin virus in suckling mice].

Authors: L A Scolaro; S E Mersich; E B Damonte
Journal: Rev Argent Microbiol Date: 1987 Jan-Mar Impact factor: 1.852

2. Argentine hemorrhagic fever.

Authors: M C Weissenbacher; R P Laguens; C E Coto
Journal: Curr Top Microbiol Immunol Date: 1987 Impact factor: 4.291

3. Cross reactivity between Junin and Tacaribe viruses as determined by neutralization test and immunoprecipitation.

Authors: E B Damonte; S E Mersich; N A Candurra; C E Coto
Journal: Med Microbiol Immunol Date: 1986 Impact factor: 3.402

4. Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

Authors: D W Cleveland; S G Fischer; M W Kirschner; U K Laemmli
Journal: J Biol Chem Date: 1977-02-10 Impact factor: 5.157

5. Nucleotide sequence of the Lassa virus (Josiah strain) S genome RNA and amino acid sequence comparison of the N and GPC proteins to other arenaviruses.

Authors: D D Auperin; J B McCormick
Journal: Virology Date: 1989-02 Impact factor: 3.616

6. Biological properties of Junin virus proteins. I. Identification of the immunogenic glycoprotein.

Authors: B Cresta; P Padula; M de Martinez Segovia
Journal: Intervirology Date: 1980 Impact factor: 1.763

7. Lymphocytic choriomeningitis virus. VII. Structural alterations of the virion by treatment with proteolytic enzymes without loss of infectivity.

Authors: M Bruns; F Lehmann-Grube
Journal: J Gen Virol Date: 1984-08 Impact factor: 3.891

A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein.

1. [Attenuation in the virulence of a mutant of Junin virus in suckling mice].

2. Argentine hemorrhagic fever.

3. Cross reactivity between Junin and Tacaribe viruses as determined by neutralization test and immunoprecipitation.

4. Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

5. Nucleotide sequence of the Lassa virus (Josiah strain) S genome RNA and amino acid sequence comparison of the N and GPC proteins to other arenaviruses.

6. Biological properties of Junin virus proteins. I. Identification of the immunogenic glycoprotein.

7. Lymphocytic choriomeningitis virus. VII. Structural alterations of the virion by treatment with proteolytic enzymes without loss of infectivity.

8. Reduced virulence of a Junin virus mutant is associated with restricted multiplication in murine cells.

9. Single amino-acid changes in HIV envelope affect viral tropism and receptor binding.

10. Polypeptide synthesis in Junín virus-infected BHK-21 cells.

1. Low-pH-induced fusion of Vero cells infected with Junin virus.

2. Measuring protein structural changes on a proteome-wide scale using limited proteolysis-coupled mass spectrometry.

3. The entry of Junin virus into Vero cells.

4. Genetic diversity in the yellow head nidovirus complex.