OBJECTIVE: The aim of this study was to assess the impact of caloric restriction diet versus caloric restriction diet combined with aerobic exercises on bone mineral density (BMD) in obese premenopausal women. SUBJECTS AND METHODS: Forty premenopausal obese women were classified randomly into two groups equal in number. The first group (group A) received caloric restriction diet, while the second (group B) received caloric restriction diet combined with a program of aerobic exercises, over 3 months. The variables measured in this study included age, weight, height, body mass index, fat weight, lean mass, fat percent, basal metabolic rate, and BMD. RESULTS: The comparison between group A and group B showed significantly higher post-treatment lean mass, basal metabolic rate, and BMD in weight-bearing bones (L2-L4 lumbar spine and total hip) in group B compared to group A. In contrast to the BMD of the weight-bearing bones, the BMD of the radius showed significant decrease between the pre- and post-treatment results in groups A and B with no significant differences between the two groups. CONCLUSION: A greater improvement in the BMD of weight-bearing bones was observed in obese premenopausal women undergoingcaloric restriction combined with exercise than in those not undergoing exercise. Anaerobic exercises incorporated into weight loss programs help offset the adverse effects of dietary restriction on bone.
RCT Entities:
OBJECTIVE: The aim of this study was to assess the impact of caloric restriction diet versus caloric restriction diet combined with aerobic exercises on bone mineral density (BMD) in obese premenopausal women. SUBJECTS AND METHODS: Forty premenopausal obesewomen were classified randomly into two groups equal in number. The first group (group A) received caloric restriction diet, while the second (group B) received caloric restriction diet combined with a program of aerobic exercises, over 3 months. The variables measured in this study included age, weight, height, body mass index, fat weight, lean mass, fat percent, basal metabolic rate, and BMD. RESULTS: The comparison between group A and group B showed significantly higher post-treatment lean mass, basal metabolic rate, and BMD in weight-bearing bones (L2-L4 lumbar spine and total hip) in group B compared to group A. In contrast to the BMD of the weight-bearing bones, the BMD of the radius showed significant decrease between the pre- and post-treatment results in groups A and B with no significant differences between the two groups. CONCLUSION: A greater improvement in the BMD of weight-bearing bones was observed in obese premenopausal women undergoing caloric restriction combined with exercise than in those not undergoing exercise. Anaerobic exercises incorporated into weight loss programs help offset the adverse effects of dietary restriction on bone.
Authors: Leanne M Redman; Leonie K Heilbronn; Corby K Martin; Anthony Alfonso; Steven R Smith; Eric Ravussin Journal: J Clin Endocrinol Metab Date: 2007-01-02 Impact factor: 5.958
Authors: D P Beavers; K M Beavers; R F Loeser; N R Walton; M F Lyles; B J Nicklas; S A Shapses; J J Newman; S P Messier Journal: Osteoarthritis Cartilage Date: 2014-04-15 Impact factor: 6.576
Authors: Kristen M Beavers; Michael P Walkup; Ashley A Weaver; Leon Lenchik; Stephen B Kritchevsky; Barbara J Nicklas; Walter T Ambrosius; Joel D Stitzel; Thomas C Register; Sue A Shapses; Anthony P Marsh; W Jack Rejeski Journal: J Bone Miner Res Date: 2018-08-07 Impact factor: 6.741