Literature DB >> 21604021

Cytotoxicity of the new antimetabolite-bisphosphonate (5-FdU-alendronate) in comparison to standard therapeutics on breast and ovarian cancer cell lines in the ATP tumor chemosensitivity assay.

Sarah Schott1, Markus Wallwiener, Beate Kootz, Harald Seeger, Tanja Fehm, Hans Neubauer.   

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Year:  2011        PMID: 21604021     DOI: 10.1007/s10637-011-9688-3

Source DB:  PubMed          Journal:  Invest New Drugs        ISSN: 0167-6997            Impact factor:   3.850


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  21 in total

1.  A promising approach for treatment of tumor-induced bone diseases: utilizing bisphosphonate derivatives of nucleoside antimetabolites.

Authors:  Monica M Reinholz; Shawn P Zinnen; Amylou C Dueck; David Dingli; Gregory G Reinholz; Leslie A Jonart; Kathleen A Kitzmann; Amy K Bruzek; Vivian Negron; Abdalla K Abdalla; Bonnie K Arendt; Anthony J Croatt; Luis Sanchez-Perez; David P Sebesta; Harri Lönnberg; Toshiyuki Yoneda; Karl A Nath; Diane F Jelinek; Stephen J Russell; James N Ingle; Thomas C Spelsberg; Henry B F Hal Dixon; Alexander Karpeisky; Wilma L Lingle
Journal:  Bone       Date:  2010-03-15       Impact factor: 4.398

2.  ATP chemosensitivity testing of new antitumor duplex drugs linking 3`-C-ethynylycytidine (ECyd) and 2´-deoxy-5-fluorouridine (5-FdU) in comparison to standard cytostatica and combinations thereof.

Authors:  Sarah Schott; Markus Wallwiener; Beate Kootz; Harald Seeger; Tanja Fehm; Hans Neubauer
Journal:  Invest New Drugs       Date:  2009-12-09       Impact factor: 3.850

3.  The cytostatic effect of 9-cis-retinoic acid, tretinoin, and isotretinoin on three different human bladder cancer cell lines in vitro.

Authors:  S Laaksovirta; P Rajala; M Nurmi; T L Tammela; M Laato
Journal:  Urol Res       Date:  1999

4.  Correlation of drug response with the ATP tumorchemosensitivity assay in primary FIGO stage III ovarian cancer.

Authors:  G Konecny; C Crohns; M Pegram; M Felber; S Lude; C Kurbacher; I A Cree; H Hepp; M Untch
Journal:  Gynecol Oncol       Date:  2000-05       Impact factor: 5.482

5.  Pilot studies of the effect of zoledronic acid (Zometa) on tumor-derived cells ex vivo in the ATP-based tumor chemosensitivity assay.

Authors:  Louise A Knight; Mark Conroy; Augusta Fernando; Marta Polak; Christian M Kurbacher; Ian A Cree
Journal:  Anticancer Drugs       Date:  2005-10       Impact factor: 2.248

Review 6.  Bone-specific drug delivery systems: approaches via chemical modification of bone-seeking agents.

Authors:  Hideki Hirabayashi; Jiro Fujisaki
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

7.  Bioluminescence of cellular ATP: a new method for evaluating cytotoxic agents in vitro.

Authors:  L Kangas; M Grönroos; A L Nieminen
Journal:  Med Biol       Date:  1984

8.  Predicting resistance to platinum-containing chemotherapy with the ATP tumor chemosensitivity assay in primary ovarian cancer.

Authors:  Hans Neubauer; Maya Stefanova; Erich Solomayer; Christoph Meisner; Manfred Zwirner; Diethelm Wallwiener; Tanja Fehm
Journal:  Anticancer Res       Date:  2008 Mar-Apr       Impact factor: 2.480

9.  Chemosensitivity testing of human tumors using a microplate adenosine triphosphate luminescence assay: clinical correlation for cisplatin resistance of ovarian carcinoma.

Authors:  P E Andreotti; I A Cree; C M Kurbacher; D M Hartmann; D Linder; G Harel; I Gleiberman; P A Caruso; S H Ricks; M Untch
Journal:  Cancer Res       Date:  1995-11-15       Impact factor: 12.701

Review 10.  Guidance on the use of bisphosphonates in solid tumours: recommendations of an international expert panel.

Authors:  M Aapro; P A Abrahamsson; J J Body; R E Coleman; R Colomer; L Costa; L Crinò; L Dirix; M Gnant; J Gralow; P Hadji; G N Hortobagyi; W Jonat; A Lipton; A Monnier; A H G Paterson; R Rizzoli; F Saad; B Thürlimann
Journal:  Ann Oncol       Date:  2007-09-28       Impact factor: 32.976

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  4 in total

Review 1.  Purinergic signalling and cancer.

Authors:  Geoffrey Burnstock; Francesco Di Virgilio
Journal:  Purinergic Signal       Date:  2013-12       Impact factor: 3.765

2.  In vitro and in vivo toxicity of 5-FdU-alendronate, a novel cytotoxic bone-seeking duplex drug against bone metastasis.

Authors:  Sarah Schott; Sonia Vallet; Robert J Tower; Seema Noor; Sanjay Tiwari; Christian Schem; Christian Busch
Journal:  Invest New Drugs       Date:  2015-05-20       Impact factor: 3.850

Review 3.  Bisphosphonate conjugation for bone specific drug targeting.

Authors:  Kristen B Farrell; Alexander Karpeisky; Douglas H Thamm; Shawn Zinnen
Journal:  Bone Rep       Date:  2018-07-03

Review 4.  Bisphosphonate-Based Conjugates and Derivatives as Potential Therapeutic Agents in Osteoporosis, Bone Cancer and Metastatic Bone Cancer.

Authors:  Zintle Mbese; Blessing A Aderibigbe
Journal:  Int J Mol Sci       Date:  2021-06-26       Impact factor: 5.923

  4 in total

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