Literature DB >> 21594555

Staphylococcus lugdunensis strain with a modified PBP1A/1B expressing resistance to β-lactams.

S D Kotsakis1, L S Tzouvelekis, L Zerva, A Liakopoulos, E Petinaki.   

Abstract

We describe for the first time the emergence of an mecA-negative Staphylococcus lugdunensis strain with a modified PBP1A/1B that expresses resistance to all β-lactams. A duplication of the tetrapeptide S(569)AYG, which is part of the transpeptidase domain of PBP1A/1B and closely located to the K(583)TG catalytic motif, was associated with this unusual phenotype.

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Year:  2011        PMID： 21594555     DOI： 10.1007/s10096-011-1289-8

Source DB:  PubMed          Journal:  Eur J Clin Microbiol Infect Dis        ISSN： 0934-9723            Impact factor:   3.267


  14 in total

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3.  Statistical potential for assessment and prediction of protein structures.

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4.  Two successfully treated cases of Staphylococcus lugdunensis endocarditis.

Authors:  Kalliopi-Stavroula Chatzigeorgiou; Christina Ikonomopoulou; Sofia Kalogeropoulou; Nikolaos Siafakas; Georgios Giannopoulos; Anastasia Antoniadou; Panayotis T Tassios; Ekaterini Tarpatzi; Efthymia Giannitsioti; Dimitrios Vlachakos; Theophanis Ikonomopoulos; Efthymia Petinaki; Loukia Zerva
Journal:  Diagn Microbiol Infect Dis       Date:  2010-12       Impact factor: 2.803

5.  Protein structure modeling with MODELLER.

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6.  Identification of dynamic structural motifs involved in peptidoglycan glycosyltransfer.

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7.  Evaluation of an anti-PBP 2a slide latex agglutination test in coagulase-negative staphylococci isolated in Greek hospitals.

Authors:  E Petinaki; V Miriagou; L S Tzouvelekis; F Hatzi; N J Legakis; A N Maniatis
Journal:  Diagn Microbiol Infect Dis       Date:  2002-04       Impact factor: 2.803

Review 8.  From clinical microbiology to infection pathogenesis: how daring to be different works for Staphylococcus lugdunensis.

Authors:  Kristi L Frank; José Luis Del Pozo; Robin Patel
Journal:  Clin Microbiol Rev       Date:  2008-01       Impact factor: 26.132

9.  Point mutations in Staphylococcus aureus PBP 2 gene affect penicillin-binding kinetics and are associated with resistance.

Authors:  C J Hackbarth; T Kocagoz; S Kocagoz; H F Chambers
Journal:  Antimicrob Agents Chemother       Date:  1995-01       Impact factor: 5.191

10.  Beta-lactams versus glycopeptides in treatment of subcutaneous abscesses infected with Staphylococcus aureus.

Authors:  C A Wood; R M Wisniewski
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  6 in total

1.  Multilocus sequence typing analysis of Staphylococcus lugdunensis implies a clonal population structure.

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Authors:  Paula Gómez; Laura Ruiz-Ripa; Rosa Fernández-Fernández; Haythem Gharsa; Karim Ben Slama; Ursula Höfle; Myriam Zarazaga; Mark A Holmes; Carmen Torres
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3.  First documented case of a Staphylococcus lugdunensis strain carrying the mecA gene in Northern Europe.

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4.  Two coagulase-negative staphylococci emerging as potential zoonotic pathogens: wolves in sheep's clothing?

Authors:  Meghan F Davis; Christine L Cain; Amy M Brazil; Shelley C Rankin
Journal:  Front Microbiol       Date:  2013-05-15       Impact factor: 5.640

5.  Novel mutations in penicillin-binding protein genes in clinical Staphylococcus aureus isolates that are methicillin resistant on susceptibility testing, but lack the mec gene.

Authors:  Xiaoliang Ba; Ewan M Harrison; Giles F Edwards; Matthew T G Holden; Anders Rhod Larsen; Andreas Petersen; Robert L Skov; Sharon J Peacock; Julian Parkhill; Gavin K Paterson; Mark A Holmes
Journal:  J Antimicrob Chemother       Date:  2013-11-11       Impact factor: 5.790

6.  Prevalence and antibiogram of coagulase negative Staphylococci in bioaerosols from different indoors of a university in India.

Authors:  Himani Kumari; Trina Chakraborti; Madhuri Singh; Maneet Kumar Chakrawarti; Kasturi Mukhopadhyay
Journal:  BMC Microbiol       Date:  2020-07-16       Impact factor: 3.605
  6 in total

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