Literature DB >> 2158809

Neurone specific enolase (NSE) in small cell lung cancer: a tumour marker of prognostic significance?

M Harding1, J McAllister, G Hulks, D Vernon, R Monie, J Paul, S B Kaye.   

Abstract

Pretreatment serum levels of neurone specific enolase (NSE) were measured in patients with small cell lung cancer (SCLC). Median values were significantly higher in patients with extensive compared with limited stage disease (48 ng ml-1 v. 17 ng ml-1: P less than 0.001). Serial NSE levels paralleled the clinical response to treatment. In 37 patients with limited SCLC, receiving identical chemotherapy, the pretreatment NSE level was of prognostic significance: with an approximate reduction in median survival of 10% for each 5 ng ml-1 incremental rise in NSE (P = 0.004).

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Year:  1990        PMID： 2158809      PMCID： PMC1971357          DOI： 10.1038/bjc.1990.134

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  13 in total

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Journal:  Thorax       Date:  1985-02       Impact factor: 9.139

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Journal:  Chest       Date:  1985-01       Impact factor: 9.410

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Authors:  L G Jørgensen; K Osterlind; H H Hansen; E H Cooper
Journal:  Br J Cancer       Date:  1988-12       Impact factor: 7.640
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  14 in total

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Journal:  CMAJ Open       Date:  2016-07-22

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Authors:  M van de Pol; A Twijnstra; G P ten Velde; P P Menheere
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

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Authors:  Jian Li; Chun-Hua Dai; Ping Chen; Jian-Nong Wu; Quan-Lei Bao; Hao Qiu; Xiao-Qin Li
Journal:  Med Oncol       Date:  2009-02-12       Impact factor: 3.064

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Authors:  P O'Shea; M Cassidy; R Freaney; P McCarthy; J Fennelly
Journal:  Ir J Med Sci       Date:  1995-01       Impact factor: 1.568

6.  Prognostic significance of serum neuron-specific enolase in small cell carcinoma of the urinary bladder.

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7.  Specific activation of glycolytic enzyme enolase 2 in BRAF V600E-mutated colorectal cancer.

Authors:  Ryohei Yukimoto; Naohiro Nishida; Tsuyoshi Hata; Shiki Fujino; Takayuki Ogino; Norikatsu Miyoshi; Hidekazu Takahashi; Mamoru Uemura; Taroh Satoh; Yamamoto Hirofumi; Tsunekazu Mizushima; Yuichiro Doki; Hidetoshi Eguchi
Journal:  Cancer Sci       Date:  2021-05-14       Impact factor: 6.716

8.  An immunohistochemical investigation of diagnostic biopsy material taken from short and long term survivors with small cell lung cancer.

Authors:  L G Bobrow; F R Hirsch; F G Hay; L Happerfield; B G Skov; K Law; R C Leonard; R L Souhami
Journal:  Br J Cancer       Date:  1992-09       Impact factor: 7.640

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Authors:  L G Jørgensen; K Osterlind; J Genollá; S A Gomm; J R Hernández; P W Johnson; J Løber; T A Splinter; M Szturmowicz
Journal:  Br J Cancer       Date:  1996-08       Impact factor: 7.640

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Authors:  M Plebani; D Basso; F Navaglia; M De Paoli; A Tommasini; A Cipriani
Journal:  Br J Cancer       Date:  1995-07       Impact factor: 7.640
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