Literature DB >> 21566010

Impact of retrievable stents on acute ischemic stroke treatment.

C Brekenfeld1, G Schroth, P Mordasini, U Fischer, M-L Mono, A Weck, M Arnold, M El-Koussy, J Gralla.   

Abstract

BACKGROUND AND
PURPOSE: Retrievable stents combine the high recanalization rate of stents and the capability of removing the thrombus offered by mechanical thrombectomy devices. We hypothesized that retrievable stents shorten time to recanalization in the multimodal approach for endovascular stroke treatment.
MATERIALS AND METHODS: Forty consecutive patients with acute ischemic stroke and undergoing endovascular therapy were included. Treatment included thromboaspiration, thrombus disruption, thrombolysis, PTA, and stent placement. In 17 patients, a retrievable stent was used (group A) in addition to multimodal therapy. The remaining 23 patients constituted group B. Baseline characteristics, occlusion sites, urokinase dose, recanalization rate, and time to recanalization were compared between the groups.
RESULTS: Median NIHSS scores were higher in group A compared with group B on admission (19 versus 12.5; P = .018) but were not significantly different at day 1 (14 versus 10; P = .6). Intra-arterial thrombolysis was used in significantly fewer patients of group A than group B (53% versus 87%, respectively; P = .017), and median urokinase dose was lower in group A than in group B (250,000 IU versus 700,000 IU; P = .006). Time to recanalization was significantly shorter in group A compared with group B (median time to recanalization 52.5 minutes versus 90 minutes, respectively; P = .001). Recanalization rate was higher in group A than group B (94% versus 78%; P = .17).
CONCLUSIONS: Addition of retrievable stents to the multimodal endovascular approach for acute ischemic stroke treatment significantly reduces time to recanalization and further increases the recanalization rate.

Entities:  

Mesh:

Year:  2011        PMID: 21566010      PMCID: PMC7966059          DOI: 10.3174/ajnr.A2494

Source DB:  PubMed          Journal:  AJNR Am J Neuroradiol        ISSN: 0195-6108            Impact factor:   3.825


  26 in total

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Authors:  P Mordasini; N Frabetti; J Gralla; G Schroth; U Fischer; M Arnold; C Brekenfeld
Journal:  AJNR Am J Neuroradiol       Date:  2010-10-21       Impact factor: 3.825

2.  Penumbra system: a novel mechanical thrombectomy device for large-vessel occlusions in acute stroke.

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4.  Internal carotid artery stent implantation in 25 patients with acute stroke: preliminary results.

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5.  Pathophysiological topography of acute ischemia by combined diffusion-weighted and perfusion MRI.

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6.  Temporary endovascular bypass: a novel treatment for acute stroke.

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7.  Self-expanding stents for recanalization of acute cerebrovascular occlusions.

Authors:  E I Levy; R Mehta; R Gupta; R A Hanel; A J Chamczuk; D Fiorella; H H Woo; F C Albuquerque; T G Jovin; M B Horowitz; L N Hopkins
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8.  Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial.

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Journal:  Stroke       Date:  2008-02-28       Impact factor: 7.914

9.  Mechanical thromboembolectomy for acute ischemic stroke: comparison of the catch thrombectomy device and the Merci Retriever in vivo.

Authors:  Caspar Brekenfeld; Gerhard Schroth; Marwan El-Koussy; Krassen Nedeltchev; Michael Reinert; Johannes Slotboom; Jan Gralla
Journal:  Stroke       Date:  2008-02-28       Impact factor: 7.914

10.  Interventional acute ischemic stroke therapy with intracranial self-expanding stent.

Authors:  Osama O Zaidat; Thomas Wolfe; Syed I Hussain; John R Lynch; Rishi Gupta; Joanna Delap; Michel T Torbey; Brian-Fred Fitzsimmons
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  24 in total

1.  Technical feasibility and application of mechanical thrombectomy with the Solitaire FR Revascularization Device in acute basilar artery occlusion.

Authors:  P Mordasini; C Brekenfeld; J V Byrne; U Fischer; M Arnold; M R Heldner; R Lüdi; H P Mattle; G Schroth; J Gralla
Journal:  AJNR Am J Neuroradiol       Date:  2012-06-21       Impact factor: 3.825

2.  Considerations about Occlusion of the Intracranial Distal Internal Carotid Artery.

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Review 5.  Stent-retriever thrombectomy: impact on the future of interventional stroke treatment.

Authors:  P Mordasini; C Zubler; K Wha-Vei Hsieh; P K Chan; J Gralla
Journal:  Clin Neuroradiol       Date:  2014-02-22       Impact factor: 3.649

6.  Inadvertent Detachment of a Retrievable Intracranial Stent: Review of Manufacturer and User Facility Device Experience.

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7.  Experimental evaluation of immediate recanalization effect and recanalization efficacy of a new thrombus retriever for acute stroke treatment in vivo.

Authors:  P Mordasini; C Brekenfeld; J V Byrne; U Fischer; M Arnold; S Jung; G Schroth; J Gralla
Journal:  AJNR Am J Neuroradiol       Date:  2012-07-26       Impact factor: 3.825

8.  Histopathological Characteristics of IV Recombinant Tissue Plasminogen -Resistant Thrombi in Patients with Acute Ischemic Stroke.

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9.  Outcome of mechanical thrombectomy with Solitaire stent as first-line intra-arterial treatment in intracranial internal carotid artery occlusion.

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10.  What the SWIFT and TREVO II trials tell us about the role of endovascular therapy for acute stroke.

Authors:  Joseph P Broderick; Gerhard Schroth
Journal:  Stroke       Date:  2013-05-16       Impact factor: 7.914

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