Literature DB >> 21558588

Creating a spread-out Bragg peak in proton beams.

David Jette1, Weimin Chen.   

Abstract

The model of Bortfeld and Schlegel (1996 Phys. Med. Biol. 41 1331-9) for determining the weights of proton beams required to create a spread-out Bragg peak (SOBP) gives a significantly tilted SOBP. However, by arbitrarily varying its parameter p, which relates the range of protons to their energy, we have been able to create satisfactory SOBPs. MCNPX Monte Carlo calculations have been carried out to determine p, demonstrating the success of this modification. Optimal values of p are tabulated for various combinations of maximum beam energy E(0) (50, 100, 150, 200 and 250 MeV) and SOBP width χ (15%, 20%, 25%, 30%, 35% and 40%), as well as for a correction factor needed to calculate the SOBP dose. An example shows the application of these results to analyzing the dose deposited by deuterons and alpha particles in broad proton beams.

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Year:  2011        PMID: 21558588     DOI: 10.1088/0031-9155/56/11/N01

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  9 in total

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2.  Physical parameter optimization scheme for radiobiological studies of charged particle therapy.

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Journal:  Phys Med       Date:  2018-06-14       Impact factor: 2.685

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Journal:  Rep Pract Oncol Radiother       Date:  2018-09-04

4.  Dual-storage phosphor proton therapy dosimetry: Simultaneous quantification of dose and linear energy transfer.

Authors:  Jufri Setianegara; Thomas R Mazur; Deshan Yang; H Harold Li
Journal:  Med Phys       Date:  2021-02-19       Impact factor: 4.071

5.  Effects of defining realistic compositions of the ocular melanoma on proton therapy.

Authors:  Sh Keshazare; S F Masoudi; F S Rasouli
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7.  Incorporating oxygenation levels in analytical DNA-damage models-quantifying the oxygen fixation mechanism.

Authors:  Frank Van den Heuvel; Anna Vella; Francesca Fiorini; Mark Brooke; Mark A Hill; Tim Maughan
Journal:  Phys Med Biol       Date:  2021-07-09       Impact factor: 3.609

8.  Evaluation of the range shifter model for proton pencil-beam scanning for the Eclipse v.11 treatment planning system.

Authors:  Witold Matysiak; Daniel Yeung; Roelf Slopsema; Zuofeng Li
Journal:  J Appl Clin Med Phys       Date:  2016-03-08       Impact factor: 2.102

9.  Secondary particle production and physical properties during dose enhancement for spread-out Bragg peaks.

Authors:  Chulhwan Hwang; Jung Hoon Kim
Journal:  Transl Cancer Res       Date:  2019-08       Impact factor: 1.241

  9 in total

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