PURPOSE: To compare colonoscopy screening/surveillance rates by level of risk for colorectal cancer based on age, personal history of adenomatous polyps or colorectal cancer, or family history of colorectal cancer. METHODS: Participants were aged 30-90 years, were seen within 5 years at Intermountain Healthcare, and had family history in the Utah Population Database. Colonoscopy rates were measured for those with/without risk factors. RESULTS: Among those aged 60-69 years, 48.4% had colonoscopy in the last 10 years, with rates declining after age 70 years. Percentages of those having had a colonoscopy in the last 10 years generally increased by risk level from 38.5% in those with a familial relative risk <1.0 to 47.6% in those with a familial relative risk >3.0. Compared with those with no family history, the odds ratio for being screened according to guidelines was higher for those with one first-degree relative diagnosed with colorectal cancer ≥ 60 years or two affected second-degree relatives (1.54, 95% confidence interval: 1.46-1.61) than those with one affected first-degree relative diagnosed <60 years or ≥2 affected first-degree relatives (1.25, 95% confidence interval: 1.14-1.37). CONCLUSIONS: Compliance with colonoscopy guidelines was higher for those with familial risk but did not correspond with the degree of risk.
PURPOSE: To compare colonoscopy screening/surveillance rates by level of risk for colorectal cancer based on age, personal history of adenomatous polyps or colorectal cancer, or family history of colorectal cancer. METHODS: Participants were aged 30-90 years, were seen within 5 years at Intermountain Healthcare, and had family history in the Utah Population Database. Colonoscopy rates were measured for those with/without risk factors. RESULTS: Among those aged 60-69 years, 48.4% had colonoscopy in the last 10 years, with rates declining after age 70 years. Percentages of those having had a colonoscopy in the last 10 years generally increased by risk level from 38.5% in those with a familial relative risk <1.0 to 47.6% in those with a familial relative risk >3.0. Compared with those with no family history, the odds ratio for being screened according to guidelines was higher for those with one first-degree relative diagnosed with colorectal cancer ≥ 60 years or two affected second-degree relatives (1.54, 95% confidence interval: 1.46-1.61) than those with one affected first-degree relative diagnosed <60 years or ≥2 affected first-degree relatives (1.25, 95% confidence interval: 1.14-1.37). CONCLUSIONS: Compliance with colonoscopy guidelines was higher for those with familial risk but did not correspond with the degree of risk.
Authors: Jan T Lowery; Nora Horick; Anita Y Kinney; Dianne M Finkelstein; Kathleen Garrett; Robert W Haile; Noralane M Lindor; Polly A Newcomb; Robert S Sandler; Carol Burke; Deirdre A Hill; Dennis J Ahnen Journal: Cancer Epidemiol Biomarkers Prev Date: 2014-02-05 Impact factor: 4.254
Authors: Laurie E Steffen; Kenneth M Boucher; Barbara H Damron; Lisa M Pappas; Scott T Walters; Kristina G Flores; Watcharaporn Boonyasiriwat; Sally W Vernon; Antoinette M Stroup; Marc D Schwartz; Sandra L Edwards; Wendy K Kohlmann; Jan T Lowery; Charles L Wiggins; Deirdre A Hill; John C Higginbotham; Randall Burt; Rebecca G Simmons; Anita Y Kinney Journal: Cancer Epidemiol Biomarkers Prev Date: 2015-06-22 Impact factor: 4.254
Authors: Lu Deng; Hong Fang; Victor K Tso; Yuanyuan Sun; Rae R Foshaug; Spencer C Krahn; Fen Zhang; Yujie Yan; Huilin Xu; David Chang; Yong Zhang; Richard N Fedorak Journal: Int J Colorectal Dis Date: 2016-12-01 Impact factor: 2.571
Authors: Chen Chen; Lingli Deng; Siwei Wei; G A Nagana Gowda; Haiwei Gu; Elena G Chiorean; Mohammad Abu Zaid; Marietta L Harrison; Joseph F Pekny; Patrick J Loehrer; Dabao Zhang; Min Zhang; Daniel Raftery Journal: J Proteome Res Date: 2015-05-13 Impact factor: 4.466
Authors: Allison E Anderson; Kevin A Henry; N Jewel Samadder; Ray M Merrill; Anita Y Kinney Journal: Clin Gastroenterol Hepatol Date: 2012-12-04 Impact factor: 11.382