| Literature DB >> 21555568 |
Amy Wells Quinkert1, Vivek Vimal, Zachary M Weil, George N Reeke, Nicholas D Schiff, Jayanth R Banavar, Donald W Pfaff.
Abstract
We review a concept of the most primitive, fundamental function of the vertebrate CNS, generalized arousal (GA). Three independent lines of evidence indicate the existence of GA: statistical, genetic, and mechanistic. Here we ask, is this concept amenable to quantitative analysis? Answering in the affirmative, four quantitative approaches have proven useful: (i) factor analysis, (ii) information theory, (iii) deterministic chaos, and (iv) application of a Gaussian equation. It strikes us that, to date, not just one but at least four different quantitative approaches seem necessary for describing different aspects of scientific work on GA.Mesh:
Year: 2011 PMID: 21555568 PMCID: PMC3176607 DOI: 10.1073/pnas.1101894108
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205