Literature DB >> 2155407

Sequence dependent modulating effect of camptothecin on the DNA-cleaving activity of the calf thymus type I topoisomerase.

I I Gromova1, V L Buchman, R A Abagyan, A V Ulyanov, I B Bronstein.   

Abstract

High-resolution mapping of topol cleavages in the regions of human DNA including the oncogene c-Ha-ras and p53, has revealed three kinds of topol cleavage sites: cleavage sites not affected by camptothecin; cleavage sites reinforced only in the presence of camptothecin, and cleavage sites which weaken in the presence of camptothecin. Statistical analysis of sequences revealed certain nucleotide or dinucleotide preferences for three groups studied. The preferences in camptothecin-reduced sites predominate upstream from the cleavage point, whereas in camptothecin-induced sites the situation is reversed. The influence of camptothecin on cleavage sites induced by two molecular forms of topol has been also studied.

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Year:  1990        PMID： 2155407      PMCID： PMC333473          DOI： 10.1093/nar/18.3.637

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  30 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  1977-09       Impact factor: 11.205

2.  [Effect of camptothecin on the DNA-relaxing and DNA-cleavage activity of calf thymus topoisomerase I].

Authors:  I B Bronshteĭn; I I Gromova; V L Bukhman; K A Kafiani
Journal:  Mol Biol (Mosk)       Date:  1989 Mar-Apr

3.  A new method for sequencing DNA.

Authors:  A M Maxam; W Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

5.  A hypothesis on a specific sequence-dependent conformation of DNA and its relation to the binding of the lac-repressor protein.

Authors:  A Klug; A Jack; M A Viswamitra; O Kennard; Z Shakked; T A Steitz
Journal:  J Mol Biol       Date:  1979-07-15       Impact factor: 5.469

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Authors:  G P Lomonossoff; P J Butler; A Klug
Journal:  J Mol Biol       Date:  1981-07-15       Impact factor: 5.469

7.  Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue.

Authors:  D J Capon; E Y Chen; A D Levinson; P H Seeburg; D V Goeddel
Journal:  Nature       Date:  1983-03-03       Impact factor: 49.962

8.  Recognition sites of eukaryotic DNA topoisomerase I: DNA nucleotide sequencing analysis of topo I cleavage sites on SV40 DNA.

Authors:  K A Edwards; B D Halligan; J L Davis; N L Nivera; L F Liu
Journal:  Nucleic Acids Res       Date:  1982-04-24       Impact factor: 16.971

9.  Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA.

Authors:  M D Been; R R Burgess; J J Champoux
Journal:  Nucleic Acids Res       Date:  1984-04-11       Impact factor: 16.971

10.  Interaction between DNA and Escherichia coli protein omega. Formation of a complex between single-stranded DNA and omega protein.

Authors:  R E Depew; L F Liu; J C Wang
Journal:  J Biol Chem       Date:  1978-01-25       Impact factor: 5.157
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  5 in total

1.  Purification and characterization of a proteolytic active fragment of DNA topoisomerase I from the brine shrimp Artemia franciscana (Crustacea Anostraca).

Authors:  G Badaracco; N Landsberger; R Benfante
Journal:  Biochem J       Date:  1992-02-15       Impact factor: 3.857

2.  Characterization of an altered DNA catalysis of a camptothecin-resistant eukaryotic topoisomerase I.

Authors:  I I Gromova; E Kjeldsen; J Q Svejstrup; J Alsner; K Christiansen; O Westergaard
Journal:  Nucleic Acids Res       Date:  1993-02-11       Impact factor: 16.971

3.  Specific cleavage of chicken alpha A-globin and human c-Ha-ras genes by two molecular forms of calf thymus topoisomerase I.

Authors:  I B Bronstein; I I Gromova; S V Razin
Journal:  Mol Cell Biochem       Date:  1991-03-13       Impact factor: 3.396

4.  Inducible and cell type-specific expression of VL30 U3 subgroups correlate with their enhancer design.

Authors:  M Nilsson; S Bohm
Journal:  J Virol       Date:  1994-01       Impact factor: 5.103

5.  Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin.

Authors:  A Tanizawa; K W Kohn; Y Pommier
Journal:  Nucleic Acids Res       Date:  1993-11-11       Impact factor: 16.971
  5 in total

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