Literature DB >> 2549395

[Effect of camptothecin on the DNA-relaxing and DNA-cleavage activity of calf thymus topoisomerase I].

I B Bronshteĭn, I I Gromova, V L Bukhman, K A Kafiani.   

Abstract

Nucleotide sequences that are cleaved by calf thymus type I topoisomerase have been determined using cloned human Ha-ras and p53 genes. Localization and relative frequency of single-strand cleavages within these sequences were observed to change in the presence of the cytotoxic alkaloid camptothecin.

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Year:  1989        PMID： 2549395

Source DB:  PubMed          Journal:  Mol Biol (Mosk)        ISSN： 0026-8984


  3 in total

1.  Sequence dependent modulating effect of camptothecin on the DNA-cleaving activity of the calf thymus type I topoisomerase.

Authors:  I I Gromova; V L Buchman; R A Abagyan; A V Ulyanov; I B Bronstein
Journal:  Nucleic Acids Res       Date:  1990-02-11       Impact factor: 16.971

2.  Specific cleavage of chicken alpha A-globin and human c-Ha-ras genes by two molecular forms of calf thymus topoisomerase I.

Authors:  I B Bronstein; I I Gromova; S V Razin
Journal:  Mol Cell Biochem       Date:  1991-03-13       Impact factor: 3.396

3.  Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin.

Authors:  A Tanizawa; K W Kohn; Y Pommier
Journal:  Nucleic Acids Res       Date:  1993-11-11       Impact factor: 16.971
  3 in total

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