Literature DB >> 21552356

Quasi- and pseudo-maximum likelihood estimators for discretely observed continuous-time Markov branching processes.

Rui Chen1, Ollivier Hyrien.   

Abstract

This article deals with quasi- and pseudo-likelihood estimation in a class of continuous-time multi-type Markov branching processes observed at discrete points in time. "Conventional" and conditional estimation are discussed for both approaches. We compare their properties and identify situations where they lead to asymptotically equivalent estimators. Both approaches possess robustness properties, and coincide with maximum likelihood estimation in some cases. Quasi-likelihood functions involving only linear combinations of the data may be unable to estimate all model parameters. Remedial measures exist, including the resort either to non-linear functions of the data or to conditioning the moments on appropriate sigma-algebras. The method of pseudo-likelihood may also resolve this issue. We investigate the properties of these approaches in three examples: the pure birth process, the linear birth-and-death process, and a two-type process that generalizes the previous two examples. Simulations studies are conducted to evaluate performance in finite samples.

Entities:  

Year:  2011        PMID: 21552356      PMCID: PMC3086408          DOI: 10.1016/j.jspi.2011.01.016

Source DB:  PubMed          Journal:  J Stat Plan Inference        ISSN: 0378-3758            Impact factor:   1.111


  15 in total

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2.  Estimation problems associated with stochastic modeling of proliferation and differentiation of O-2A progenitor cells in vitro.

Authors:  A Zorin; M Mayer-Proschel; M Noble; A Y Yakovlev
Journal:  Math Biosci       Date:  2000-10       Impact factor: 2.144

3.  An alternative stochastic model of generation of oligodendrocytes in cell culture.

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4.  A stochastic model to analyze clonal data on multi-type cell populations.

Authors:  Ollivier Hyrien; Margot Mayer-Pröschel; Mark Noble; Andrei Yakovlev
Journal:  Biometrics       Date:  2005-03       Impact factor: 2.571

5.  Quantitative insight into proliferation and differentiation of oligodendrocyte type 2 astrocyte progenitor cells in vitro.

Authors:  A Y Yakovlev; K Boucher; M Mayer-Proschel; M Noble
Journal:  Proc Natl Acad Sci U S A       Date:  1998-11-24       Impact factor: 11.205

6.  Mathematical and experimental approaches to identify and predict the effects of chemotherapy on neuroglial precursors.

Authors:  Ollivier Hyrien; Jörg Dietrich; Mark Noble
Journal:  Cancer Res       Date:  2010-11-05       Impact factor: 12.701

7.  Inference for an age-dependent, multitype branching-process model of mast cells.

Authors:  J Nedelman; H Downs; P Pharr
Journal:  J Math Biol       Date:  1987       Impact factor: 2.259

8.  An age-dependent branching process model for the analysis of CFSE-labeling experiments.

Authors:  Ollivier Hyrien; Rui Chen; Martin S Zand
Journal:  Biol Direct       Date:  2010-06-22       Impact factor: 4.540

9.  Saddlepoint approximations to the moments of multitype age-dependent branching processes, with applications.

Authors:  O Hyrien; R Chen; M Mayer-Pröschel; M Noble
Journal:  Biometrics       Date:  2009-06-09       Impact factor: 2.571

10.  Stochastic modeling of oligodendrocyte generation in cell culture: model validation with time-lapse data.

Authors:  Ollivier Hyrien; Ibro Ambeskovic; Margot Mayer-Proschel; Mark Noble; Andrei Yakovlev
Journal:  Theor Biol Med Model       Date:  2006-05-17       Impact factor: 2.432

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  2 in total

1.  Asymptotic behavior of cell populations described by two-type reducible age-dependent branching processes with non-homogeneous immigration().

Authors:  Ollivier Hyrien; Nikolay M Yanev
Journal:  Math Popul Stud       Date:  2012-10-05       Impact factor: 0.720

2.  Two-Type Age-Dependent Branching Processes with Inhomogeneous Immigration as Models of Renewing Cell Populations.

Authors:  Ollivier Hyrien; Nikolay M Yanev
Journal:  Pliska       Date:  2011
  2 in total

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