Literature DB >> 21552049

The efficacy of nonoperative management of acute complicated diverticulitis.

Sekhar Dharmarajan1, Steven R Hunt, Elisa H Birnbaum, James W Fleshman, Matthew G Mutch.   

Abstract

BACKGROUND: The surgical management of acute complicated diverticulitis has evolved to avoid emergency surgery in favor of elective resection. The optimal manner to accomplish this goal remains debatable.
OBJECTIVE: The purpose of this study was to examine the efficacy of nonoperative management of acute diverticulitis with abscess or perforation.
DESIGN: A retrospective review was performed of an institutional review board-approved database of patients admitted with a diagnosis of acute complicated diverticulitis from 1995 to 2008. Patient demographics, disease manifestation, management, and outcomes were collected. SETTINGS: This study was conducted at a tertiary care hospital/referral center. PATIENTS: Patients were included who presented with complicated diverticulitis defined as having an associated abscess or free air diagnosed by CT scan. MAIN OUTCOME MEASURES: Primary end points were the success of nonoperative management and need for surgery during the initial admission.
RESULTS: One hundred thirty-six patients were identified with perforated diverticulitis: 19 had localized free air, 45 had abscess <4 cm or distant free air measuring <2 cm, 66 had abscess >4 cm or distant free air >2 cm, and 6 had distant free air with free fluid. Thirty-eight patients (28%) required percutaneous abscess drains and 37 (27%) required parenteral nutrition. Only 5 patients (3.7%) required urgent surgery at the time of admission, and 7 (5%) required urgent surgery for failed nonoperative management. Thus, the overall success rate of nonoperative management was 91%. One hundred twenty-four of 131 (95%) patients were treated with nonoperative management successfully. Twenty-five of 27 (92.5%) patients with free air remote from the perforation site were successfully treated nonoperatively.
CONCLUSIONS: Nonoperative management of acute complicated diverticulitis is highly effective. For patients with free air remote from the site of perforation, nonoperative management is able to convert an emergent situation into an elective one in 93% of cases. The decision to attempt nonoperative therapy must be made based on the patient's physiologic state and associated comorbidities.

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Mesh:

Year:  2011        PMID: 21552049     DOI: 10.1007/DCR.0b013e31820ef759

Source DB:  PubMed          Journal:  Dis Colon Rectum        ISSN: 0012-3706            Impact factor:   4.585


  56 in total

1.  Percutaneous drainage for hinchey Ib and II acute diverticulitis with abscess improves outcomes.

Authors:  David R Rosen; Emily G Pott; Kyle G Cologne; Sang W Lee; Glenn T Ault; Daniel J Grabo; Damon H Clark; Aaron M Strumwasser
Journal:  Turk J Gastroenterol       Date:  2019-11       Impact factor: 1.852

2.  Uncomplicated Acute Diverticulitis: Identifying Risk Factors for Severe Outcomes.

Authors:  Rebekah Jaung; Malsha Kularatna; Jason P Robertson; Ryash Vather; David Rowbotham; Andrew D MacCormick; Ian P Bissett
Journal:  World J Surg       Date:  2017-09       Impact factor: 3.352

3.  International Variation in Emergency Operation Rates for Acute Diverticulitis: Insights into Healthcare Value.

Authors:  Michael K Y Hong; Anita R Skandarajah; Rose D Higgins; Omar D Faiz; Ian P Hayes
Journal:  World J Surg       Date:  2017-08       Impact factor: 3.352

4.  Nonoperative management of perforated acute diverticulitis with extraluminal air: results and risk factors of failure.

Authors:  Alberto Titos-García; Jose M Aranda-Narváez; Laura Romacho-López; Antonio J González-Sánchez; Isaac Cabrera-Serna; Julio Santoyo-Santoyo
Journal:  Int J Colorectal Dis       Date:  2017-07-17       Impact factor: 2.571

Review 5.  Failure of nonoperative management in patients with acute diverticulitis complicated by abscess: a systematic review.

Authors:  Hayley Fowler; Mahir Gachabayov; Dale Vimalachandran; Rachael Clifford; Guy R Orangio; Roberto Bergamaschi
Journal:  Int J Colorectal Dis       Date:  2021-03-07       Impact factor: 2.571

Review 6.  Current Options for the Emergency Management of Diverticular Disease and Options to Reduce the Need for Colostomy.

Authors:  Dimitra Theodoropoulos
Journal:  Clin Colon Rectal Surg       Date:  2018-06-22

7.  The clinical significance of extraluminal air in Hinchey 1a diverticulitis: results from a retrospective cohort study with 10-year follow-up.

Authors:  Jeremy Meyer; Anna Caruso; Elin Roos; Alexandre Balaphas; Christian Toso; Pierre-Alexandre Poletti; Frédéric Ris; Nicolas C Buchs
Journal:  Int J Colorectal Dis       Date:  2019-11-07       Impact factor: 2.571

8.  Perforated diverticulitis in the North of England: trends in patient outcomes, management approach and the influence of subspecialisation.

Authors:  T E Baldock; L R Brown; R C McLean
Journal:  Ann R Coll Surg Engl       Date:  2019-06-03       Impact factor: 1.891

9.  Surgery for diverticulitis: a re-evaluation of the changing trends.

Authors:  Tafadzwa P Makarawo; Steffan Eichenauer; Uma Shah; Amy Jaeger; Alasdair McKendrick; Vijay K Mittal
Journal:  Int Surg       Date:  2014 Jul-Aug

10.  Non-operative treatment of right-sided colonic diverticulitis has good long-term outcome: a review of 226 patients.

Authors:  Ker-Kan Tan; Jiayi Wong; Richard Sim
Journal:  Int J Colorectal Dis       Date:  2012-10-16       Impact factor: 2.571

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