BACKGROUND: Little is known about health-related quality of life (HRQoL) in the long term after stroke. AIM: The aim of this study was to assess the level of, and factors associated with, HRQoL at 7 years post-stroke. METHODS: All stroke cases from a prospective community-based stroke incidence study (excluding subarachnoid haemorrhage) were assessed 7 years after stroke. HRQoL was measured with the Assessment of Quality of Life instrument. Proportional odds ordinal logistic regression was used to determine factors associated with HRQoL at 7 years post-stroke. RESULTS: Overall, 1321 stroke cases were recruited. Seven years after stroke, 413 (31.2%) were alive and 328 (79.4%) were assessed. Those assessed were less often current smokers pre-stroke than those not assessed (p<0.01). Seventy-six survivors (23%) had very poor HRQoL (range: -0.038 to 0.100). Factors present at 7 years that were associated with better 7-year HRQoL were independence in instrumental activities of daily living (IADL) (estimated OR=11.2, 95% CI 4.87 to 25.6, p<0.001), independence in basic activities of daily living (BADL) (OR=4.53, 95% CI 2.03 to 10.1, p<0.001), independence in IADL and BADL (OR=9.90, 95% CI 4.51 to 21.7, p<0.001), male gender (OR=1.89, 95% CI 1.21 to 2.96, p=0.005) and lesser handicap (trend: OR=3.47, 95% CI 2.51 to 4.79, p<0.001). Participants' HRQoL scores tended to be lower when HRQoL assessments were completed by proxy (OR=0.13, 95% CI 0.06 to 0.31, p<0.001). CONCLUSION: At 7 years post-stroke, 68.8% had died and a substantial proportion of survivors had poor HRQoL. Factors such as handicap, BADL and IADL could be targeted to improve HRQoL in long-term survivors of stroke.
BACKGROUND: Little is known about health-related quality of life (HRQoL) in the long term after stroke. AIM: The aim of this study was to assess the level of, and factors associated with, HRQoL at 7 years post-stroke. METHODS: All stroke cases from a prospective community-based stroke incidence study (excluding subarachnoid haemorrhage) were assessed 7 years after stroke. HRQoL was measured with the Assessment of Quality of Life instrument. Proportional odds ordinal logistic regression was used to determine factors associated with HRQoL at 7 years post-stroke. RESULTS: Overall, 1321 stroke cases were recruited. Seven years after stroke, 413 (31.2%) were alive and 328 (79.4%) were assessed. Those assessed were less often current smokers pre-stroke than those not assessed (p<0.01). Seventy-six survivors (23%) had very poor HRQoL (range: -0.038 to 0.100). Factors present at 7 years that were associated with better 7-year HRQoL were independence in instrumental activities of daily living (IADL) (estimated OR=11.2, 95% CI 4.87 to 25.6, p<0.001), independence in basic activities of daily living (BADL) (OR=4.53, 95% CI 2.03 to 10.1, p<0.001), independence in IADL and BADL (OR=9.90, 95% CI 4.51 to 21.7, p<0.001), male gender (OR=1.89, 95% CI 1.21 to 2.96, p=0.005) and lesser handicap (trend: OR=3.47, 95% CI 2.51 to 4.79, p<0.001). Participants' HRQoL scores tended to be lower when HRQoL assessments were completed by proxy (OR=0.13, 95% CI 0.06 to 0.31, p<0.001). CONCLUSION: At 7 years post-stroke, 68.8% had died and a substantial proportion of survivors had poor HRQoL. Factors such as handicap, BADL and IADL could be targeted to improve HRQoL in long-term survivors of stroke.
Authors: Mandip S Dhamoon; Leslie A McClure; Carole L White; Helena Lau; Oscar Benavente; Mitchell S V Elkind Journal: J Stroke Cerebrovasc Dis Date: 2013-10-28 Impact factor: 2.136
Authors: Lynne R Sheffler; Paul N Taylor; Douglas D Gunzler; Jaap H Buurke; Maarten J Ijzerman; John Chae Journal: Arch Phys Med Rehabil Date: 2013-02-08 Impact factor: 3.966
Authors: Ramon Luengo-Fernandez; Alastair M Gray; Linda Bull; Sarah Welch; Fiona Cuthbertson; Peter M Rothwell Journal: Neurology Date: 2013-10-09 Impact factor: 9.910
Authors: Raed A Joundi; Joel Adekanye; Alexander A Leung; Paul Ronksley; Eric E Smith; Alexander D Rebchuk; Thalia S Field; Michael D Hill; Stephen B Wilton; Lauren C Bresee Journal: J Am Heart Assoc Date: 2022-06-22 Impact factor: 6.106