Literature DB >> 21549641

Management of Asherman's syndrome.

Charles M March1.   

Abstract

Intrauterine adhesions (IUA) or Asherman's syndrome is a multifaceted condition which is being diagnosed with increasing frequency. Although it usually occurs following curettage of the pregnant or recently pregnant uterus, any uterine surgery can lead to IUA. Most women with IUA have amenorrhoea or hypomenorrhoea, but some have normal menses. Those who have amenorrhoea may also have cyclic pelvic pain secondary to 'trapped' menses and the accompanying retrograde menstruation may lead to endometriosis. In addition to menstrual disorders, most women with IUA will present with infertility or recurrent spontaneous abortion. Over the last four decades hysteroscopy has become the standard method to diagnose and treat this condition. Various techniques for adhesiolysis and for prevention of scar reformation have been advocated. The most efficacious appears to be the use of miniature scissors for adhesiolysis and the placement of a balloon stent inside the uterus immediately after surgery. Post-operative oestrogen therapy is prescribed in order to stimulate endometrial regrowth. Follow-up studies to assure resolution of the IUA are mandatory before the patient attempts to conceive as is careful monitoring of pregnancies for cervical incompetence, placenta accreta and intrauterine growth restriction.
Copyright © 2010. Published by Elsevier Ltd.

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Year:  2010        PMID: 21549641     DOI: 10.1016/j.rbmo.2010.11.018

Source DB:  PubMed          Journal:  Reprod Biomed Online        ISSN: 1472-6483            Impact factor:   3.828


  55 in total

Review 1.  The Role of Stem Cells in the Etiology and Pathophysiology of Endometriosis.

Authors:  Demetra Hufnagel; Fei Li; Emine Cosar; Graciela Krikun; Hugh S Taylor
Journal:  Semin Reprod Med       Date:  2015-09-16       Impact factor: 1.303

2.  Preventive effects of transplantation of oral mucosal epithelial cells seeded on a decellularized amniotic membrane in a model of intrauterine adhesion.

Authors:  Xing Chen; Yingfang Zhou
Journal:  Int J Clin Exp Pathol       Date:  2018-03-01

3.  Metformin Promotes Regeneration of the Injured Endometrium Via Inhibition of Endoplasmic Reticulum Stress-Induced Apoptosis.

Authors:  Xin-Xin Xu; Si-Si Zhang; Hui-Long Lin; Qi Lin; Lai-En Shen; Emmanuel Ansong; Xue-Qing Wu
Journal:  Reprod Sci       Date:  2018-11-22       Impact factor: 3.060

4.  Effect of stem cell application on Asherman syndrome, an experimental rat model.

Authors:  Sevtap Kilic; Beril Yuksel; F Pinarli; A Albayrak; B Boztok; T Delibasi
Journal:  J Assist Reprod Genet       Date:  2014-06-29       Impact factor: 3.412

5.  Perivascular Stem Cell-Derived Cyclophilin A Improves Uterine Environment with Asherman's Syndrome via HIF1α-Dependent Angiogenesis.

Authors:  Mira Park; Seok-Ho Hong; So Hee Park; Yeon Sun Kim; Seung Chel Yang; Hye-Ryun Kim; Songmi Noh; Sunghun Na; Hyung Keun Lee; Hyunjung J Lim; Sang Woo Lyu; Haengseok Song
Journal:  Mol Ther       Date:  2020-05-20       Impact factor: 11.454

6.  Logistic regression analyses of factors affecting fertility of intrauterine adhesions patients.

Authors:  Xingping Zhao; Yunzhi Liu; Aiqian Zhang; Bingsi Gao; Qing Feng; Huan Huang; Xiuting Zhu; Xin Sun; Dabao Xu
Journal:  Ann Transl Med       Date:  2020-02

7.  Cold scissors ploughing technique in hysteroscopic adhesiolysis: a comparative study.

Authors:  Xingping Zhao; Aiqian Zhang; Bingsi Gao; Arvind Burjoo; Huan Huang; Dabao Xu
Journal:  Ann Transl Med       Date:  2020-02

8.  A preliminary study on a patented intrauterine stent in the treatment of recurrent intrauterine adhesions with poor prognosis.

Authors:  Huan Huang; Lingxiao Zou; Aiqian Zhang; Xingping Zhao; Dabao Xu; Min Xue
Journal:  Ann Transl Med       Date:  2020-02

Review 9.  Focus on the Primary Prevention of Intrauterine Adhesions: Current Concept and Vision.

Authors:  Wen-Ling Lee; Chia-Hao Liu; Min Cheng; Wen-Hsun Chang; Wei-Min Liu; Peng-Hui Wang
Journal:  Int J Mol Sci       Date:  2021-05-13       Impact factor: 5.923

10.  Patient-reported menstrual and obstetric outcomes following hysteroscopic adhesiolysis for Asherman syndrome.

Authors:  Blanca Morales; Peter Movilla; Joyce Wang; Jennifer Wang; Alexandria Williams; Tammy Chen; Himabindu Reddy; Jovana Tavcar; Megan Loring; Stephanie Morris; Keith Isaacson
Journal:  F S Rep       Date:  2021-01-11
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