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Literature DB >> 21549304

A web of interactions at the ends.

Abstract

The synthesis of telomeric DNA by telomerase entails repeated cycles of reverse transcription on a short RNA template. In this issue of Molecular Cell, Robart and Collins (2011) describe a set of interactions between human telomerase RNA, protein domains, and the substrate DNA that drives the intricate reaction cycle.

Entities: Gene Species

Year: 2011 PMID： 21549304 PMCID： PMC3093669 DOI： 10.1016/j.molcel.2011.04.014

Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970

11 in total

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Authors: Chantal Autexier; Neal F Lue
Journal: Annu Rev Biochem Date: 2006 Impact factor: 23.643

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Authors: Neal F Lue
Journal: J Biol Chem Date: 2005-05-18 Impact factor: 5.157

3. Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.

Authors: Steven A Jacobs; Elaine R Podell; Thomas R Cech
Journal: Nat Struct Mol Biol Date: 2006-02-05 Impact factor: 15.369

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Authors: C W Greider
Journal: Mol Cell Biol Date: 1991-09 Impact factor: 4.272

5. Reverse transcribing the code for chromosome stability.

Authors: Steven E Artandi; Julia Promisel Cooper
Journal: Mol Cell Date: 2009-12-11 Impact factor: 17.970

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Authors: C W Greider; E H Blackburn
Journal: Nature Date: 1989-01-26 Impact factor: 49.962

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Authors: J Lingner; T R Hughes; A Shevchenko; M Mann; V Lundblad; T R Cech
Journal: Science Date: 1997-04-25 Impact factor: 47.728

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Authors: M Cohn; E H Blackburn
Journal: Science Date: 1995-07-21 Impact factor: 47.728

9. Structure of the Tribolium castaneum telomerase catalytic subunit TERT.

Authors: Andrew J Gillis; Anthony P Schuller; Emmanuel Skordalakes
Journal: Nature Date: 2008-08-31 Impact factor: 49.962

10. Direct involvement of the TEN domain at the active site of human telomerase.

Authors: Julie Jurczyluk; Amanda S Nouwens; Jessica K Holien; Timothy E Adams; George O Lovrecz; Michael W Parker; Scott B Cohen; Tracy M Bryan
Journal: Nucleic Acids Res Date: 2010-11-03 Impact factor: 16.971

2 in total

1. The CDC13-STN1-TEN1 complex stimulates Pol α activity by promoting RNA priming and primase-to-polymerase switch.

Authors: Neal F Lue; Jamie Chan; Woodring E Wright; Jerard Hurwitz
Journal: Nat Commun Date: 2014-12-12 Impact factor: 14.919

2. STN1-POLA2 interaction provides a basis for primase-pol α stimulation by human STN1.

Authors: Swapna Ganduri; Neal F Lue
Journal: Nucleic Acids Res Date: 2017-09-19 Impact factor: 16.971

2 in total